- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Streptococcal Infections and Treatments
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Use and Resistance
- Bacterial biofilms and quorum sensing
- Vibrio bacteria research studies
- Antibiotics Pharmacokinetics and Efficacy
- Neonatal and Maternal Infections
- Salmonella and Campylobacter epidemiology
- Pneumonia and Respiratory Infections
- Infections and bacterial resistance
- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- Bacterial Infections and Vaccines
- Mycobacterium research and diagnosis
- Cystic Fibrosis Research Advances
- Sepsis Diagnosis and Treatment
- Nosocomial Infections in ICU
- Antifungal resistance and susceptibility
- Infective Endocarditis Diagnosis and Management
- Clostridium difficile and Clostridium perfringens research
- Gut microbiota and health
- Neutropenia and Cancer Infections
- Amoebic Infections and Treatments
Post Graduate Institute of Medical Education and Research
2016-2025
Institute of Medical Sciences and Sum Hospital
2025
University of Calcutta
2024
Institute of Post Graduate Medical Education and Research
2008-2023
Newcastle University Singapore
2023
Assam Medical College
2021
Czech Academy of Sciences, Institute of Microbiology
2000-2020
National Institute of Science Education and Research
2020
All India Institute of Medical Sciences
2018
Karolinska Institutet
2016
The presence of persister cells and small-colony variants (SCVs) has been associated with enhanced antibiotic resistance many organisms in biofilms. This study investigated whether persisters and/or SCVs contribute to the Staphylococcus aureus A detailed dose-dependent killing biofilms planktonic five antibiotics (oxacillin, cefotaxime, amikacin, ciprofloxacin vancomycin) was analysed by treating them each at a concentration 0-100 microg ml(-1) 37 degrees C for 48 h. biofilm all showed -...
The pathogenesis of non-alcoholic fatty liver disease (NAFLD) is multifactorial. There sparse literature on the role small intestinal bacterial overgrowth (SIBO) and toll-like receptor (TLR) signaling in NAFLD. present study evaluated relationship SIBO with expression TLR genes patients NAFLD.A total 142 subjects composed NAFLD (n = 60, mean age 38.7 ± 10.4 years), chronic viral hepatitis (CVH) 32, 39.5 10.6 healthy volunteers 50, 36.56 4.2 years) were enrolled study. Duodenal fluid was...
Bacterial biofilms are implicated in a wide range of implant-based and chronic infections. These infections often associated with adverse therapeutic outcomes, owing to the decreased antibiotic susceptibility compared their planktonic counterparts. This altered biofilm has been attributed multiple factors, including reduced penetration. Although several studies have addressed role penetration barrier biofilm-associated drug resistance, it remains inconclusive. study was done elucidate...
The Indian Council of Medical Research, in 2013, initiated the Antimicrobial Resistance Surveillance & Research Network (AMRSN) to enable compilation data on six pathogenic groups antimicrobial resistance from country. overarching aim this network was understand extent and pattern (AMR) use evidence guide strategies control spread AMR. This article describes conception implementation AMR surveillance for India. Also described are challenges, limitations benefits approach. Data have shown...
Contents: Executive Summary Introduction Methodology Definition, Epidemiology and Risk Factors Diagnosis of Asthma Management Stable Acute Exacerbations Miscellaneous Issues in EXECUTIVE SUMMARY is defined as a chronic inflammatory disorder the airways which manifests itself recurrent episodes wheezing, breathlessness, chest tightness cough. It characterized by bronchial hyper-responsiveness variable airflow obstruction, that often reversible either spontaneously or with treatment. The...
BackgroundHealth-care-associated infections (HAIs) cause significant morbidity and mortality globally, including in low-income middle-income countries (LMICs). Networks of hospitals implementing standardised HAI surveillance can provide valuable data on burden, identify monitor prevention gaps. Hospitals many LMICs use case definitions developed for higher-resourced settings, which require human resources laboratory imaging tests that are often not available.MethodsA network 26...
To study the clinical profile and outcome of patients with necrotising soft-tissue infections.Prospective study.Teaching hospital, India.75 (54 male 21 female), mean age 40 years (range 8 months-85 years).Patients were uniformly managed by initial resuscitation, debridement, topical wound care, systemic antibiotics, enteral hyperalimentation.Morbidity mortality.Aetiology infections included major minor trauma, skin postoperative infections. 22 diabetic. The extremities involved in 57...
The spectrum of organisms causing sepsis is different in developing countries. Data on the recent trends are limited. This study was conducted a tertiary care neonatal unit Northern India. All inborn babies with blood-culture-positive from 1995 to 2006 were divided into two epochs, viz. 1998 (epoch I) and 2001 II). Organisms grouped early (<72 h) late onset (> or =72 groups. overall incidence sepsis, stratified by weight groups, organism profile days life, sepsis-related mortality...
Background: Neonatal illness is a leading cause of death worldwide; sepsis one the main contributors. The etiologies community-acquired neonatal bacteremia in developing countries have not been well characterized. Methods: Infants <2 months age brought with to selected health facilities Bangladesh, Bolivia, Ghana, India, Pakistan and South Africa were evaluated, blood cultures taken if they considered ill enough be admitted hospital. Organisms isolated using standard culture techniques....
Childhood community acquired pneumonia (CAP) is a significant problem in developing countries, and confirmation of microbial etiology important for individual, as well public health. However, there paucity data from large cohort, examining multiple biological specimens diverse pathogens (bacteria viruses). The Community Acquired Pneumonia Etiology Study (CAPES) was designed to address this knowledge gap.We enrolled children with CAP (based on WHO IMCI criteria tachypnea cough or breathing...
An outbreak of nosocomial fungemia due to the unusual yeast, Pichia anomala occurred in pediatric wards our hospital over a period 23 months (April 1996 February 1998). A total 379 neonates and children (4.2% admissions) were infected. The probable index case was admitted emergency ward, with subsequent transmission premature nursery, intensive care units, other wards. Carriage on hands health personnel likely be responsible for dissemination fungus. could only controlled after education...