Joseph L. Mathew
A5033018831- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Vaccine Coverage and Hesitancy
- Asthma and respiratory diseases
- Neonatal Respiratory Health Research
- Tracheal and airway disorders
- Child Nutrition and Water Access
- Respiratory and Cough-Related Research
- Health Systems, Economic Evaluations, Quality of Life
- Congenital Diaphragmatic Hernia Studies
- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Clinical practice guidelines implementation
- Tuberculosis Research and Epidemiology
- Viral gastroenteritis research and epidemiology
- Pediatric health and respiratory diseases
- Pleural and Pulmonary Diseases
- COVID-19 Clinical Research Studies
- Inhalation and Respiratory Drug Delivery
- Health Policy Implementation Science
- Global Maternal and Child Health
- Infectious Diseases and Tuberculosis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Virology and Viral Diseases
- Meta-analysis and systematic reviews
Post Graduate Institute of Medical Education and Research
2016-2025
Institute of Medical Sciences
2016-2024
Christian Medical College & Hospital
2024
Institute of Post Graduate Medical Education and Research
2008-2023
Hospital for Sick Children
2012-2022
University of Toronto
2013-2022
KU Leuven
2022
British Columbia Children's Hospital
2022
SickKids Foundation
2013-2022
Howard University
2021-2022
Lower respiratory infections are a leading cause of morbidity and mortality around the world. The Global Burden Diseases, Injuries, Risk Factors (GBD) Study 2016, provides an up-to-date analysis burden lower in 195 countries. This study assesses cases, deaths, aetiologies spanning past 26 years shows how infection has changed people all ages.
The association of air pollution with multiple adverse health outcomes is becoming well established, but its negative economic impact less appreciated. It important to elucidate this for the states India.
The global epidemic of childhood and adolescent obesity its immediate as well long-term consequences for obese individuals society a whole cannot be overemphasized. Obesity in adolescence is associated with an increased risk adult clinically significant affecting the cardiovascular metabolic systems. Importantly, additionally complicated by obstructive sleep apnea (OSA), occurring up to 60% children. OSA, which diagnosed using gold standard polysomnogram (PSG), characterised snoring,...
Vaccine hesitancy is a continuum of behaviors ranging from delay in receipt to vaccination refusal. Prior studies have typically focused on high-income countries, where vaccine particularly prevalent more affluent groups, but the relationship between socioeconomic status and Low- Middle-Income Countries (LMICs) less clear. The aim this study was describe five LMICs. Mothers children Sirajganj, Bangladesh (n = 60), Shanghai, China 788), Addis Ababa, Ethiopia 341), Guatemala City...
<h2>Summary</h2><h3>Background</h3> India has made substantial progress in improving child survival over the past few decades, but a comprehensive understanding of mortality trends at disaggregated geographical levels is not available. We present detailed analysis subnational to inform efforts aimed meeting National Health Policy (NHP) and Sustainable Development Goal (SDG) targets for mortality. <h3>Methods</h3> assessed under-5 rate (U5MR) neonatal (NMR) from 2000 2017 5 × km grids across...
An evidence-based approach is considered the gold standard for health decision-making. Sometimes, a guideline panel might judge certainty that desirable effects of an intervention clearly outweigh its undesirable as high, but body supportive evidence indirect. In such cases, application Grading Recommendations, Assessment, Development and Evaluations (GRADE) grading strength recommendations inappropriate. Instead, GRADE Working Group has recommended developing ungraded best or good practice...
Background The International Society for Human and Animal Mycology (ISHAM) working group proposed recommendations managing allergic bronchopulmonary aspergillosis (ABPA) a decade ago. There is need to update these due advances in diagnostics therapeutics. Methods An international expert was convened develop guidelines ABPA (caused by Aspergillus spp.) mycosis (ABPM; caused fungi other than adults children using modified Delphi method (two online rounds one in-person meeting). We defined...
Childhood community acquired pneumonia (CAP) is a significant problem in developing countries, and confirmation of microbial etiology important for individual, as well public health. However, there paucity data from large cohort, examining multiple biological specimens diverse pathogens (bacteria viruses). The Community Acquired Pneumonia Etiology Study (CAPES) was designed to address this knowledge gap.We enrolled children with CAP (based on WHO IMCI criteria tachypnea cough or breathing...
The impact of vaccine hesitancy on childhood immunization in low- and middle-income countries remains largely uncharacterized. This study describes the sociodemographic patterns Chandigarh, India. Mothers children &lt;5 years old were sampled from a two-stage cluster, systematic sample based Anganwadi child care centers Chandigarh. Vaccine was measured using 10-item Hesitancy Scale, which dichotomized. A multivariable logistic regression assessed association between socioeconomic factors...
Background: Adaptation of existing guidelines can be an efficient way to develop contextualized recommendations. Transparent reporting the adaptation approach support transparency and usability adapted guidelines. Objective: To extension RIGHT (Reporting Items for practice Guidelines in HealThcare) statement (including recommendations that have been adopted, adapted, or developed de novo), RIGHT-Ad@pt checklist. Design: A multistep process was followed checklist: establishing a working...
Respiratory syncytial virus is a major cause of lower respiratory tract infection morbidity and mortality in children globally, causing 3·2–3·6 million hospitalisations more than 100 000 deaths annually younger 5 years, 99% which occur low-income middle-income countries (LMICs).1Li Y Wang X Blau DM et al.Global, regional, national disease burden estimates acute infections due to years 2019: systematic analysis.Lancet. 2022; 399: 2047-2064Summary Full Text PDF PubMed Scopus (187) Google...
Summary Background and Aim Endobronchial ultrasound‐guided transbronchial needle aspiration (EBUS‐TBNA) endoscopic ultrasound with an echobronchoscope‐guided fine (EUS‐B‐FNA) are useful modalities in the evaluation of mediastinal lymphadenopathy adults; however, there is sparse data children. The aim this multicenter study to describe efficacy safety EBUS‐TBNA EUS‐B‐FNA children undefined etiology. Methods Retrospective analysis consecutive pediatric (<18 years) subjects who underwent or...
To inform actions at the district level under National Nutrition Mission (NNM), we assessed prevalence trends of child growth failure (CGF) indicators for all districts in India and inequality between within states.We CGF (stunting, wasting underweight) from 2000 to 2017 across India, aggregated 5 × km grid estimates, using accessible data various surveys with subnational geographical information. The states were categorised into three groups their Socio-demographic Index (SDI) levels...
Childhood and adolescence require adequate amount of micronutrients for normal growth development. The primary objective study was to assess the prevalence deficiencies Vitamins (Vitamin A, 25 Hydroxy Vitamin D, B12 Folate) minerals (Calcium, Zinc, Selenium Iron), among urban school going children aged 6-11 12-16 years in ten cities India. Secondary find association between micronutrient with sociodemographic anthropometric indicators.A multi-center cross-sectional conducted across...