A5008312766- Neonatal Respiratory Health Research
- Neuroscience of respiration and sleep
- Congenital Diaphragmatic Hernia Studies
- Infant Development and Preterm Care
- Breastfeeding Practices and Influences
- Infant Nutrition and Health
- Neonatal Health and Biochemistry
- COVID-19 Impact on Reproduction
- Maternal and Neonatal Healthcare
- Infant Health and Development
- Respiratory viral infections research
- Airway Management and Intubation Techniques
- Pneumonia and Respiratory Infections
- Cardiac Arrest and Resuscitation
- Erythrocyte Function and Pathophysiology
- Global Maternal and Child Health
- Childhood Cancer Survivors' Quality of Life
- Maternal and fetal healthcare
- Maternal and Perinatal Health Interventions
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Assisted Reproductive Technology and Twin Pregnancy
- Tracheal and airway disorders
- Neonatal and Maternal Infections
- Neonatal and fetal brain pathology
- Pharmaceutical studies and practices
Hospital Ramos Mejía
2020-2024
University of Buenos Aires
2015-2024
Hospital de Niños de la Santísima Trinidad
2012-2024
Infant Foundation
2011-2021
Hospital Italiano de Buenos Aires
2021
Dirección Regional de Salud del Callao
2021
Pediatrics and Genetics
2019
Favaloro Foundation
2014
Sanatorio Otamendi y Miroli
1989-2005
Lancet Laboratories
2005
Ten critically ill newborn infants presenting with documented septicemia were treated antibiotics and supportive measures that included assisted ventilation, large blood transfusions other volume expanders, sodium bicarbonate, vasoactive drugs. Upon failure of the above treatment to improve infants' rapidly deteriorating condition development sclerema, exchange fresh whole performed repeated up four times. Seven ten showed immediate improvement ultimately survived. IgM IgA rose consistently...
Respiratory syncytial virus is a major cause of lower respiratory tract infection morbidity and mortality in children globally, causing 3·2–3·6 million hospitalisations more than 100 000 deaths annually younger 5 years, 99% which occur low-income middle-income countries (LMICs).1Li Y Wang X Blau DM et al.Global, regional, national disease burden estimates acute infections due to years 2019: systematic analysis.Lancet. 2022; 399: 2047-2064Summary Full Text PDF PubMed Scopus (187) Google...
The kidney is the most damaged organ in asphyxiated full-term infants. Experiments rabbits and rats have shown that renal adenosine acts as a vasoconstrictive metabolite after hypoxemia and/or ischemia, contributing to fall glomerular filtration rate (GFR) fraction. Vasoconstriction produced by can be inhibited nonspecific receptor antagonist, theophylline. Gouyon Guignard performed studies newborn adult subjected normocapnic hypoxemia. Their results clearly showed hypoxemia-induced drop GFR...
Objective. The administration of recombinant human erythropoietin (rHuEPO), started after the first 2 weeks life, reduces transfusion requirement in premature infants. However, its use throughout when anemia results predominantly from phlebotomy losses, remains controversial. We investigated whether early rHuEPO would reduce total and/or number transfusions life. Methods. randomized 114 infants with birth weight (BW) <1250 g to receive (1250 units/kg/week; IV; group:n = 57) or placebo...
The high burden of respiratory syncytial virus (RSV) infection in young children disproportionately occurs low- and middle-income countries (LMICs). PROUD (Preventing RespiratOry virUs unDerdeveloped countries) Taskforce 24 RSV worldwide experts assessed key needs for prevention LMICs, including vaccine newer preventive measures.A global, survey-based study was undertaken 2021. An online questionnaire developed following three meetings the panellists wherein factors related to infection, its...
Improvements in perinatal and neonatal care have markedly increased the survival of premature infants during last two decades, particular born very preterm or extremely preterm.Accordingly, attention both families medical caregivers has increasingly shifted from a focus on avoidance severe complications, to quality later outcome.This led an nutritional infants, since considerable evidence shown that nutrition is not only related infant growth, immediate functions, length hospital stay, but...
Rationale: Bronchopulmonary dysplasia increases the risk of disability in extremely preterm infants. Although pathophysiology remains uncertain, prior exposure to intermittent hypoxemia may play a role this relationship. Objectives: To determine association between prolonged episodes and severe bronchopulmonary dysplasia. Methods: A post hoc analysis infants Canadian Oxygen Trial who survived 36 weeks' postmenstrual age was performed. saturations <80% for ⩾1 minute proportion time per day...
Abstract Objective To evaluate COVID-19 pandemic preparedness, available resources, and guidelines for neonatal care delivery among health providers in low- middle-income countries (LMICs) across all continents. Study design Cross-sectional, web-based survey administered between May June, 2020. Results Of 189 invited participants 69 LMICs, we received 145 (77%) responses from 58 (84%) countries. The provides significant challenges to care, particularly low-income Respondents noted...
Infants born through meconium-stained amniotic fluid (MSAF) are at risk of meconium aspiration syndrome (MAS), a life-threatening respiratory disorder. Conflicting claims made about the effectiveness intrapartum suctioning MSAF by oropharyngeal and nasopharyngeal routes. This randomized, controlled trial was conducted 11 Argentinian centers 1 in United States. A total 2514 patients with any consistency, gestational age least 37 weeks cephalic presentation, were randomly assigned to...
Aim: To describe a term newborn with acquired severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and multisystem involvement including seizures associated to ischemic lesions in the brain. Background: Coronavirus disease 2019 (COVID-19) is predominantly infection, but it may affect many other systems. Most pediatric COVID-19 cases range from asymptomatic mild-moderate disease. There are no specific clinical signs described for neonatal infections. In children, central...
The administration of oxygen to infants via nasal cannulas is now a common practice in neonatal units although the inspired concentration reaching patient's airway unknown. We measured hypopharyngeal 10 who were receiving and assessed impact changes flow rate concentration. Weaning these by reducing rate, even if are slight, produces clinically important airway. Such poorly tolerated with chronic lung disease. Changing concentration, rather than alone, provides greater precision likely avoid...