A5068706267- Neonatal Respiratory Health Research
- Respiratory viral infections research
- Congenital Diaphragmatic Hernia Studies
- Neonatal and Maternal Infections
- Neonatal and fetal brain pathology
- Infant Nutrition and Health
- Sepsis Diagnosis and Treatment
- Infant Development and Preterm Care
- Preterm Birth and Chorioamnionitis
- Neuroscience of respiration and sleep
- Pneumonia and Respiratory Infections
- Tracheal and airway disorders
- Infant Health and Development
- Cytomegalovirus and herpesvirus research
- Neonatal Health and Biochemistry
- Streptococcal Infections and Treatments
- Respiratory Support and Mechanisms
- Congenital Heart Disease Studies
- Viral gastroenteritis research and epidemiology
- Blood Coagulation and Thrombosis Mechanisms
- Lymphatic Disorders and Treatments
- Breastfeeding Practices and Influences
- Bacterial Infections and Vaccines
- Metabolism and Genetic Disorders
- Pediatric Hepatobiliary Diseases and Treatments
Medical University of Graz
2016-2025
University of Graz
1998-2024
Zentrum für Kinderheilkunde
2006-2024
Quadram Institute
2022
Royal College of Surgeons in Ireland
2020
San Francisco General Hospital
2020
Hospital General Universitario Morales Meseguer
2020
Düzce Üniversitesi
2020
King's College London
2020
Instituto Murciano de Investigación Biosanitaria
2020
The reliability of procalcitonin (PCT) and interleukin‐6 (IL‐6) was determined compared with that C‐reactive protein (CRP) in the diagnosis early‐onset sepsis neonate within first 12 h life. ROC analysis values 41 neonates blood‐cultures‐positive clinical those 27 uninfected revealed sensitivities for PCT (≥6ng/mL), IL‐6 (≥60pg/mL), CRP (≥2.5 mg/L) 77%, 54%, 69% specificities 91%, 100% 96%, respectively. Sensitivity at ≥8 mg/L 49% ( p = 0.012 to PCT). Conclusion : most sensitive diagnostic parameter
We evaluated the causes for neonatal thrombocytopenia (NT), duration of NT, and indications platelet transfusions (PT) by means a retrospective cohort study over 23-year period. Neonates with NT were identified via ICD-10 code D69.6. Of 371 neonates (1.8/1000 live births) majority (312; 84.1%) had early onset thrombocytopenia, 282 (76%) preterm born. The most frequent late sepsis asphyxia. mean was 10.2 days negatively correlated (KK = - 0.35) number PT. PT given to 78 (21%) neonates, 38...
Preterm infants with very low birthweight are at serious risk for necrotizing enterocolitis. To functionally analyse the principles of three successful preventive NEC regimens, we characterize fecal samples 55 (<1500 g, n = 383, female 22) longitudinally (two weeks) respect to gut microbiome profiles (bacteria, archaea, fungi, viruses; targeted 16S rRNA gene sequencing and shotgun metagenomics), microbial function, virulence factors, antibiotic resistances metabolic profiles, including human...
Respiratory syncytial virus is a major cause of lower respiratory tract infection morbidity and mortality in children globally, causing 3·2–3·6 million hospitalisations more than 100 000 deaths annually younger 5 years, 99% which occur low-income middle-income countries (LMICs).1Li Y Wang X Blau DM et al.Global, regional, national disease burden estimates acute infections due to years 2019: systematic analysis.Lancet. 2022; 399: 2047-2064Summary Full Text PDF PubMed Scopus (187) Google...
Our aim was to analyze C-reactive protein (CRP) values in term and preterm infants correlate non-infection-associated increases with various neonatal disorders.Retrospective cohort study that included all newborns hospitalized at a tertiary care center between 2004 2007 documented CRP the first 3 days of life. Analysis differences cases sepsis negative newborns.For diagnosis blood culture proven (19 14 cases, respectively) 353 179 newborns, cut-off 8 mg/L had sensitivities 53% 86%...
To assess the cost-effectiveness of palivizumab, a monoclonal antibody against respiratory syncytial virus (RSV), in infants at high risk for severe RSV lower tract infection, such as premature infants, with bronchopulmonary dysplasia, and those congenital heart disease, based on long-term epidemiologic data from Austria.A decision-tree model was used, analysis lifetime follow-up investigating palivizumab versus no infection prevention. The primary perspective study that healthcare system,...
To perform a systematic review assessing accuracy and completeness of diagnostic studies procalcitonin (PCT) for early-onset neonatal sepsis (EONS) using the Standards Reporting Diagnostic Accuracy (STARD) initiative. EONS, diagnosed during first 3 days life, remains common serious problem. Increased PCT is potentially useful marker but reports in literature are contradictory. There several possible explanations divergent results including quality reporting clinical usefulness ruling or out...
Neonatal abstinence syndrome (NAS) is usually treated with opiate derivatives and supported nonpharmacological treatment.This prospective, randomized, controlled, blinded, single-center study was carried out between March 2009 November 2014. Newborn infants diagnosed NAS after maternal opioid substitution therapy were eligible for inclusion. Infants randomly allocated to the acupuncture group (combining laser pharmacological of morphine phenobarbital) or control (pharmacological alone)....
Morbidity due to respiratory syncytial virus (RSV) disease is still high in infants and children worldwide during the first two five years of life. Certain categories high-risk with increased morbidity mortality attributed RSV have been identified are included national recommendations for prophylaxis monoclonal antibody palivizumab. Most guidelines recommend palivizumab preterm born less than or equal 32 weeks gestational age without bronchopulmonary dysplasia, those between 33 35 additional...
The aim of the study was to determine burden respiratory syncytial virus (RSV) and influenza disease during COVID-19 pandemic at 2 Austrian urban pediatric centers between October 1, 2019 April 30, 2022.