Raja Dhar

ORCID: 0000-0002-6742-5674
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About
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Research Areas
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Asthma and respiratory diseases
  • Cystic Fibrosis Research Advances
  • Neonatal Respiratory Health Research
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Respiratory and Cough-Related Research
  • Inhalation and Respiratory Drug Delivery
  • Tracheal and airway disorders
  • Respiratory Support and Mechanisms
  • COVID-19 Clinical Research Studies
  • Pediatric health and respiratory diseases
  • Respiratory viral infections research
  • Lung Cancer Diagnosis and Treatment
  • Pleural and Pulmonary Diseases
  • Medical Imaging and Pathology Studies
  • Obstructive Sleep Apnea Research
  • Long-Term Effects of COVID-19
  • Antifungal resistance and susceptibility
  • Esophageal and GI Pathology
  • Sarcoidosis and Beryllium Toxicity Research
  • Tuberculosis Research and Epidemiology
  • COVID-19 and healthcare impacts
  • Ultrasound in Clinical Applications
  • Childhood Cancer Survivors' Quality of Life
  • COVID-19 and Mental Health

Sujata Birla Hospital and Medical Research Center
2023-2025

Medical College and Hospital, Kolkata
2021-2024

Indian Institute of Management Shillong
2024

Institute of Public Health Bengaluru
2024

Fortis Hospital
2014-2023

AMRI Hospitals
2021-2023

Nippon Medical School
2023

Calcutta Research Group
2023

Hospital Kuala Lumpur
2023

Post Graduate Institute of Medical Education and Research
2019-2022

Gingivo-buccal oral squamous cell carcinoma (OSCC-GB), an anatomical and clinical subtype of head neck (HNSCC), is prevalent in regions where tobacco-chewing common. Exome sequencing (n=50) recurrence testing (n=60) reveals that some significantly frequently altered genes are specific to OSCC-GB (USP9X, MLL4, ARID2, UNC13C TRPM3), while others shared with HNSCC (for example, TP53, FAT1, CASP8, HRAS NOTCH1). We also find new recurrent amplifications DROSHA, YAP1) or homozygous deletions...

10.1038/ncomms3873 article EN cc-by-nc-nd Nature Communications 2013-12-02

Interstitial lung disease (ILD) is a heterogeneous group of acute and chronic inflammatory fibrotic diseases. Existing ILD registries have had variable findings. Little known about the clinical profile ILDs in India.To characterize new-onset India by creating prospective using multidisciplinary discussion (MDD) to validate diagnoses.Adult patients Indian origin living with (27 centers, 19 cities, March 2012-June 2015) without malignancy or infection were included. All connective tissue (CTD)...

10.1164/rccm.201607-1484oc article EN American Journal of Respiratory and Critical Care Medicine 2016-09-29

Bronchiectasis is a common but neglected chronic lung disease. Most epidemiological data are limited to cohorts from Europe and the USA, with few low-income middle-income countries. We therefore aimed describe characteristics, severity of disease, microbiology, treatment patients bronchiectasis in India.The Indian registry multicentre, prospective, observational cohort study. Adult (≥18 years) CT-confirmed were enrolled 31 centres across India. Patients due cystic fibrosis or traction...

10.1016/s2214-109x(19)30327-4 article EN cc-by-nc-nd The Lancet Global Health 2019-08-08

Background The International Society for Human and Animal Mycology (ISHAM) working group proposed recommendations managing allergic bronchopulmonary aspergillosis (ABPA) a decade ago. There is need to update these due advances in diagnostics therapeutics. Methods An international expert was convened develop guidelines ABPA (caused by Aspergillus spp.) mycosis (ABPM; caused fungi other than adults children using modified Delphi method (two online rounds one in-person meeting). We defined...

10.1183/13993003.00061-2024 article EN cc-by-nc European Respiratory Journal 2024-02-29

Flexible bronchoscopy (FB) is commonly performed by respiratory physicians for diagnostic as well therapeutic purposes. However, practices vary widely across India and worldwide. The three major organizations of the country supported a national-level expert group that formulated comprehensive guideline document FB based on detailed appraisal available evidence. These guidelines are an attempt to provide bronchoscopist with most scientifically sound practical approach bronchoscopy. It...

10.4103/lungindia.lungindia_108_19 article EN cc-by-nc-sa Lung India 2019-01-01

Background Identifying risk factors for poor outcomes can help with stratification and targeting of treatment. Risk mortality exacerbations have been identified in bronchiectasis but almost exclusively studied European North American populations. This study investigated the outcome a large population patients enrolled India. Methods The Multicentre Bronchiectasis Audit Research Collaboration (EMBARC) Respiratory Network India (EMBARC-India) registry is prospective observational adults...

10.1183/13993003.00611-2022 article EN cc-by-nc European Respiratory Journal 2022-10-13

Background A validated 4-point sputum colour chart can be used to objectively evaluate the levels of airway inflammation in bronchiectasis patients. In European Bronchiectasis Registry (EMBARC), we tested whether would associated with disease severity and clinical outcomes. Methods We a prospective, observational registry adults conducted 31 countries. Patients who did not produce spontaneous were excluded from analysis. The Murray was at baseline follow-up visits. Key outcomes frequency...

10.1183/13993003.01554-2023 article EN cc-by-nc European Respiratory Journal 2024-04-01

Understanding the aetiology and characteristics of patients with bronchiectasis is vital for developing strategies to reduce burden disease; however, geographical variations in these characteristics, which may have important implications diagnosis treatment,1, 2 make it difficult formulate a uniform strategy investigation. Here, we describe illness treatment among Korean compare results those from three geographically ethnically diverse regions: Australia, Europe India. The Multicentre...

10.1111/resp.14059 article EN Respirology 2021-04-19

Over the past decade, endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has become an indispensable tool in diagnostic armamentarium of pulmonologist. As expertise with EBUS-TBNA evolved and several innovations have occurred, indications for its use expanded. However, aspects are still not standardized. Hence, evidence-based guidelines needed to optimize yield safety EBUS-TBNA. For this purpose, a working group experts from India was constituted. A detailed...

10.4103/lungindia.lungindia_510_22 article EN cc-by-nc-sa Lung India 2023-06-26

Introduction Current bronchiectasis guidelines advise against the use of inhaled corticosteroids (ICS) except in patients with associated asthma, allergic bronchopulmonary aspergillosis (ABPA) and/or chronic obstructive pulmonary disease (COPD). This study aimed to describe ICS across Europe. Methods Patients were enrolled into European Bronchiectasis Registry from 2015 2022. grouped users and non-users at baseline clinical characteristics investigated. followed up for outcomes exacerbation,...

10.1136/thorax-2024-221825 article EN cc-by-nc Thorax 2025-03-23

After admission to hospital, COVID-19 progresses in a substantial proportion of patients critical disease that requires intensive care unit (ICU) admission.In pragmatic, non-blinded trial, 387 aged 40-90 years were randomised receive treatment with SoC plus doxycycline (n = 192) or only 195). The primary outcome was the need for ICU as judged by attending physicians. Three types analyses carried out outcome: "Intention treat" (ITT) based on randomisation; "Per protocol" (PP), excluding not...

10.1371/journal.pone.0280745 article EN cc-by PLoS ONE 2023-01-23

Background: Bronchoscopic lung cryobiopsy (BLC) is a novel technique for obtaining tissue the diagnosis of diffuse parenchymal diseases. The procedure performed using several different variations technique, resulting in an inconsistent diagnostic yield and variable risk complications. There unmet need standardization technical aspects BLC. Methodology: This position statement framed by group comprising experts from fields pulmonary medicine, thoracic surgery, pathology, radiology under aegis...

10.4103/lungindia.lungindia_75_18 article EN cc-by-nc-sa Lung India 2019-01-01

Although a simple and useful pulmonary function test, spirometry remains underutilized in India. The Indian Chest Society National College of Physicians (India) jointly supported an expert group to provide recommendations for Based on scientific grading available published evidence, as well other international recommendations, we propose consensus statement planning, performing interpreting systematic manner across all levels healthcare We stress the use standard equipment, need quality...

10.4103/lungindia.lungindia_300_18 article EN cc-by-nc-sa Lung India 2019-01-01

Pleural effusion is a common problem in our country, and most of these patients need invasive tests as they can’t be evaluated by blood alone. The simplest them diagnostic pleural aspiration, techniques such medical thoracoscopy are being performed more frequently than ever before. However, physicians India treat empirically, leading to delays diagnosis, misdiagnosis complications from wrong treatments. This situation must change, the adoption evidence-based protocols urgently needed....

10.4103/lungindia.lungindia_33_24 article EN cc-by-nc-sa Lung India 2024-04-30

In comparison to the worldwide burden of asthma, although India contributes 13% total asthma prevalence, it has a threefold higher mortality rate and more than twofold DALYs, indicating substantial gap in diagnosis treatment. Asthma causes significant suffering, affecting people’s quality life draining country’s resources; therefore, we must devise ways means fill these gaps. The most successful cost-efficient strategy battle is form strong partnerships between patients, general public,...

10.4103/lungindia.lungindia_518_23 article EN cc-by-nc-sa Lung India 2024-04-30

Background: Reference values of peak expiratory flow (PEF) in Indian adults have to date been derived locally, using an old (Wright) scale meter. There are thus no reliable reference for PEF Indians and this formed the aim study. Materials Methods: A European Union (EU) meter (PFM) was used respiratory health demographic questionnaire administered 1000 male female from randomly selected locations country multi centric The represented different geographic, ethnic, socioeconomic backgrounds....

10.4103/0022-3859.132311 article EN Journal of Postgraduate Medicine 2014-01-01
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