A5059892673- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Air Quality and Health Impacts
- Pediatric health and respiratory diseases
- Respiratory Support and Mechanisms
- Inhalation and Respiratory Drug Delivery
- Respiratory and Cough-Related Research
- Climate Change and Health Impacts
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Energy and Environment Impacts
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Tuberculosis Research and Epidemiology
- Emergency and Acute Care Studies
- Child and Adolescent Health
- Public Health and Nutrition
- Cystic Fibrosis Research Advances
- Pulmonary Hypertension Research and Treatments
- Health Promotion and Cardiovascular Prevention
- Chronic Disease Management Strategies
- Child Nutrition and Water Access
- Global Health and Epidemiology
- Noise Effects and Management
- Insects and Parasite Interactions
- Antifungal resistance and susceptibility
Bombay Hospital
2012
Abstract Background Although COPD among non-smokers (NS-COPD) is common, little known about this phenotype. We compared NS-COPD subjects with smoking (S-COPD) patients in a rural Indian population using variety of clinical, physiological, radiological, sputum cellular and blood biomarkers. Methods Two hundred ninety (118 healthy, 79 S-COPD, 93 NS-COPD) performed pre- post-bronchodilator spirometry were followed for 2 years to study the annual rate decline lung function. Body plethysmography,...
India has one of the highest disease burdens in world. A better understanding what ails will help policy makers plan appropriate health-care services and infrastructure development, design medical education curricula, identify health research priorities that are relevant to needs country. The POSEIDON study aimed record prevalence symptoms conditions for which patients visit a primary practitioner India.We randomly selected 12 000 general practitioners, physicians, paediatricians from 880...
Chronic obstructive pulmonary disease (COPD) causes substantial burden of in developed countries, but there are limited data from Africa. We aimed to estimate the prevalence COPD Tanzania and identify risk factors associated with it.This was a cross-sectional descriptive survey involving adults aged ≥35 years. collected on symptoms using Burden Obstructive Lung Diseases questionnaire. Spirometry performed diagnosed based post-bronchodilator forced expiratory volume 1 s/forced vital capacity...
Metabolic adaptation in immune cells is necessary to modulate cell function as it intricately coupled with intracellular metabolism. We aimed characterize the metabolic state of human peripheral blood mononuclear (PBMCs) after long-term exposure tobacco smoke smokers preserved lung and COPD subjects.PBMCs were isolated from healthy non-smokers (HNS), (HS) subjects, cultured mitochondrial respiration while utilizing glucose (glycolysis), fatty acids (β-oxidation) or pyruvate (direct Krebs'...
Although spirometry is the gold-standard diagnostic test for obstructive airways diseases, it remains poorly utilised in clinical practice. We aimed to investigate use of across India, change its usage over a period time and understand reasons under-utilisation. Two nationwide surveys were conducted years 2005 2013, among four groups doctors: chest physicians (CPs), general (GenPs), practitioners (GPs) paediatricians (Ps). A total 1,000 from each randomly selected our database 2013. These 52...
COPD is the second leading cause of death and disability adjusted life years (DALYs) in India, yet, it remains poorly recognized. We aimed to study level awareness urban slums Pune city India its neighboring rural areas. All male female subjects above age 30 residing 13 randomly selected (total population 3000) 7 villages were invited participate this cross-sectional community survey. After obtaining written informed consent, trained health workers (CHWs) administered a questionnaire that...
Background: According to the 2019 Global Burden of Disease (GBD) report, India contributes an estimated 12.9% global asthma cases (34.3 million) but a disproportionate 42.3% all deaths. Also, causes 4.83 million disability-adjusted life years (DALYs) annually in India, four times more than China, which ranks second. Hypothesis: We hypothesised that this increase deaths and suffering could be due under-use inhaled corticosteroids. Methods: Using number each state union territory from GBD...
<b>Instead of using % predicted values or Z-scores to define and quantify respiratory abnormality in oscillometry, fixed cut-off will likely give more accurate discrimination</b>https://bit.ly/3vVmIyE
Background: Poverty is an important surrogate marker for obstructive airway diseases (OAD). Slum constitutes a habitat wherein various poverty related parameters are perpetually prevalent in the ambience. 1/6th of world population lives slums yet there no information regarding their health status context to asthma and COPD. Aims: We investigated prevalence chronic-bronchitis symptoms associated risk-factors slum habitats Pune city. Methodology: 7062 adult slum-dwellers living 12 city were...
Abstract Inhalation therapy is the basis of pharmacological management asthma and COPD. Most patients are trained on correct use inhalers by health professionals but after that do continue to take them correctly at home remains largely unknown. Video recording inhalation technique using a smartphone can be used evaluate inhaler home. Through this pilot study, we aimed understand whether training given in outpatient clinic translates into good practices video application platform smartphone....
Background: Reference values of peak expiratory flow (PEF) in Indian adults have to date been derived locally, using an old (Wright) scale meter. There are thus no reliable reference for PEF Indians and this formed the aim study. Materials Methods: A European Union (EU) meter (PFM) was used respiratory health demographic questionnaire administered 1000 male female from randomly selected locations country multi centric The represented different geographic, ethnic, socioeconomic backgrounds....
Delhi is one of the most polluted cities in world with annual average ambient PM10 and PM2.5 levels exceeding World Health Organization standards by over 15 fold. We aimed to study prevalence respiratory allergic symptoms asthma among adolescent children living (D) compare it lesser Kottayam (K) Mysore (M) located Southern India.4361 boys girls between age group 13-14 16-17 years from 12 randomly selected private schools D, K, M were invited participate. Modified expanded International Study...
BackgroundThe Global Asthma Network phase I study in India aimed to the prevalence, time trends, and associated risk factors of allergic rhinitis eczema among 6-7-year-old, 13-14-year-old school children their parents. Objectives: The objective was understand current prevalence Allergic Rhinitis Eczema 6-7-year-olds, 13-14-year-olds parents/guardians for newer directions health care providers, policy makers academicians.MethodsCross-sectional, multicenter using self- parent-administered...
Cough is a common symptom reported in PC. We aimed to determine the prevalence of cough and its associated diagnoses as by primary care physicians (PCPs) across all age groups POSEIDON study India. <b>Methods</b>: 13,225 general practitioners (GPs), (GenPs) pediatricians (Ps) from 880 urban cities towns were randomly selected invited participate this 1-day point study. Clean data was entered Epi-Info software. Simple descriptive analysis performed. <b>Results:</b> 7400 PCPs (60.6% GPs, 20.8%...
Diwali or the festival of lights is most popular celebrated in India when firecrackers are burnt by almost every household for 3 days. Levels ambient air pollution reported to be very high during India. In this study, we aimed measure and compare personal exposure levels particulate matter <2.5 μm mass median aerodynamic diameter (PM2.5) burning six commonly used firecracker types India.Sparklers, ground spinners, flower pots, pulpuls, a garland 1000 sounding crackers, snake tablets were...
Background: Clinical research in India experienced dramatic changes with series of stringent guidelines introduced by regulatory authorities. These posed significant challenges for the clinical trial industry. Objective: To assess perceptions and opinion Indian Investigators about new guidelines. Methods: We developed a survey questionnaire on recent which was hosted web portal. Seventy-three investigators from participated survey. Results: Central registration Ethics Committees (ECs) agreed...
<b>Background:</b> We have previously reported that respiratory diseases are the most common for which patients visit doctors in India. A better understanding of disease pattern and symptoms will help determine appropriate health care management strategies set up necessary services. This pilot study was aimed to investigate <b>Method:</b> total 1560 Pulmonologists, Intensivists Pediatricians from our database were invited participate this 7-day across The questionnaire based on ICD-10...
COPD is the 2nd leading cause of deaths and DALYs in India likely contributes to a huge economic burden. Most health care expenditure out-of-pocket little contributed by government medical insurance. In this study, we aimed examine for patients visiting government, semi-private private hospitals/clinics. <b>Methods:</b> 239 doctor diagnosed spirometry confirmed (168 Males, Mean age 66.9 ± 8.9 years) mild-to-very severe (8 mild, 76 moderate, 130 severe-very severe) on medications at least one...