- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Insect and Arachnid Ecology and Behavior
- Neurobiology and Insect Physiology Research
- COVID-19 Clinical Research Studies
- Cancer, Hypoxia, and Metabolism
- Insect and Pesticide Research
- Dental Health and Care Utilization
- Child Nutrition and Water Access
- Oral microbiology and periodontitis research
- Bladder and Urothelial Cancer Treatments
- SARS-CoV-2 and COVID-19 Research
- Epigenetics and DNA Methylation
- Lung Cancer Diagnosis and Treatment
- Pulmonary Hypertension Research and Treatments
- COVID-19 diagnosis using AI
- Asthma and respiratory diseases
- Nutritional Studies and Diet
- Toxin Mechanisms and Immunotoxins
- Obstructive Sleep Apnea Research
- Iron Metabolism and Disorders
- Tuberculosis Research and Epidemiology
- Streptococcal Infections and Treatments
King George's Medical University
2019-2024
University of Delhi
2018-2024
Dr. Ram Manohar Lohia Institute of Medical Sciences
2022-2024
Kumaun University
2024
University of Allahabad
2024
National Institute of Technology Durgapur
2023
Indian Institute of Toxicology Research
2017-2022
Creative Commons
2022
Government of Uttar Pradesh
2020
Indian Institute of Technology Dhanbad
2020
Childhood and adolescence require adequate amount of micronutrients for normal growth development. The primary objective study was to assess the prevalence deficiencies Vitamins (Vitamin A, 25 Hydroxy Vitamin D, B12 Folate) minerals (Calcium, Zinc, Selenium Iron), among urban school going children aged 6-11 12-16 years in ten cities India. Secondary find association between micronutrient with sociodemographic anthropometric indicators.A multi-center cross-sectional conducted across...
In many insects, the accessory gland, a secretory tissue of male reproductive system, is essential for fertility. Male gland major source proteinaceous secretions, collectively called as seminal proteins (or proteins), which upon transfer, manipulate physiology and behavior mated females. Insect hormones such ecdysteroids juvenoids play key role in development protein synthesis but little known about underlying molecular players their mechanism action. Therefore, present study, we examined...
Estrogen related receptors (ERRs), categorized as orphan nuclear receptors, are critical for energy homeostasis and somatic development. However, significance of ERRs in the development reproductive organs/organelles/cells remain poorly understood, albeit their homology to estrogen receptors. In this context, here, we show that knockdown ERR testes leads improperly developed with mis-regulation genes (aly, mia, bruce, bam, bgcn, fzo eya) involved spermatogenesis, resulting reduced male...
Background Micronutrient deficiency (MD) is associated with deficits in cognitive functioning of children. However, no comprehensive multicentric study has been conducted India to explore the role multiple MD cognition children and adolescents. The present aimed association level general intelligence specific functions, urban school-going adolescents across ten cities India. Method Cross-sectional study, enrolled participants aged 6–16 years. Blood samples were collected for biochemical...
Taxanes, microtubule stabilizing agents, are extensively used in the treatment of non-small cell lung cancer (NSCLC). However, their clinical effectiveness remains restricted owing to significant adverse effects and drug resistance. Nanotechnology may guide chemotherapeutic drugs directly selectively malignant cells, improving therapeutic efficiency. In present study, we synthesized polylactic-co-glycolic acid (PLGA) based nanoparticles encapsulating docetaxel evaluated efficacy carcinoma...
Background Community-acquired pneumonia (CAP) is the leading cause of under-five mortality in India. An increased risk has been reported cases hypoxic pneumonia. Methods The primary objective this study was to assess proportion children aged 2–59 months, hospitalized with CAP, as well socio-demographic, clinical, and radiological features associated it. secondary determine among CAP. This prospective, observational conducted four districts Northern India, between January 2015 April 2021. A...
Background: Coronavirus disease 2019 (COVID-19) is a novel infectious caused by SARS CoV-2 that emerged in Wuhan, China, and has rapidly spread worldwide. The mortality rate of critically ill COVID-19 patients high. Objective: To assess the severity, different clinical symptoms, comorbidities pneumonia vaccinated vs. non-vaccinated patients. Methods: In this single-center, cross-sectional study, 142 with were enrolled. characteristics, comorbidities, outcomes also assessed. Results: Of...
Background: Cholangiocarcinoma (CCA) is the second most common primary hepatic tumor. In recent years, its prognosis has improved because of wide resections and establishment local treatment chemotherapy. Objective: To determine diagnosis cholangiocarcinoma Methods: A cross-sectional study was conducted at First affiliated hospital Xinjiang Medical University, Urumqi, Xinjiang, China which performed between December 2023 to July 2024, The total number patients in our were 100. Male 55 female...
Abstract Adequate nutrition is necessary during childhood and early adolescence for adequate growth development. Hence, the objective of study was to assess association between dietary intake blood levels minerals (calcium, iron, zinc, selenium) vitamins (folate, vitamin B12, A, D) in urban school going children aged 6–16 years India, a multicentric cross-sectional study. Participants were enrolled from randomly selected schools ten cities. Three-day food data collected using 24-h recall...
Background Chronic obstructive pulmonary disease (COPD) cannot be properly characterised by a single metric, forced expiratory volume in the first second (FEV1), due to its complexity and heterogeneity. The GOLD 2017 report contained ABCD evaluation method measure airflow limitation, symptoms, and/or exacerbation risk. Objective purpose of this study was explore relationship between clinical characteristics groups or stages patients with COPD. Methods This cross-sectional observational...
There is strong evidence that periodontal disease (PD) related to various systemic diseases including respiratory diseases. Dental plaque the primal cause of PD, and it can also be used as a reservoir lung pathogens. After inhalation, variety infections. In addition, low nutritional status immuneosuppression due treatment or progression may affect oral health hospitalized patients with nontubercular Here, we aimed assess in problems.We have enrolled 100 ill this study. Periodontal clinical...
René-Théophile-Hyacinthe Laennec in his book "Treatise of the Diseases Chest" discussed emphysema 1821. Chronic obstructive pulmonary disease (COPD) has been around for at least 202 years, from 1821 to 2023 (but itself is much older than that). It believed that William Briscoe first used term COPD June 1965, 9th Aspen Emphysema Conference. was defined by CIBA guest symposium 1959 and American Thoracic Society Committee on Diagnostic Standards 1962; recent definition released Global...
Community acquired pneumonia (CAP) is a leading cause of under-five mortality in India and Streptococcus pneumoniae the main bacterial pathogen for it. Pneumococcal Conjugate Vaccine 13 (PCV13) has been introduced phased manner, national immunization program since 2017/2018. The primary objective this study was to evaluate effectiveness PCV13 on chest radiograph (CXR)-confirmed pneumonia, children hospitalized with WHO-defined severe CAP.This prospective, multi-site test-negative conducted...
Tuberculosis (TB) continues to be a major global health concern impacting millions of people each year. Beyond its outward symptoms TB can have significant negative influence on psychological and cause anguish in those who are afflicted. The purpose this review is recapitulate the frequency contributing variables discomfort patients. Previous studies show varying prevalence rates distress which frequently manifests as stress, worry, depression. Numerous factors such sociodemographic...