A5035602497- Antibiotic Resistance in Bacteria
- Escherichia coli research studies
- Vibrio bacteria research studies
- Viral gastroenteritis research and epidemiology
- Salmonella and Campylobacter epidemiology
- Urinary Tract Infections Management
- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Enterobacteriaceae and Cronobacter Research
- Bacteriophages and microbial interactions
- Aquaculture disease management and microbiota
- Clostridium difficile and Clostridium perfringens research
- Infections and bacterial resistance
- Infection Control in Healthcare
- Nosocomial Infections in ICU
- Antimicrobial Resistance in Staphylococcus
- Genomics and Phylogenetic Studies
- Child Nutrition and Water Access
- Antibiotics Pharmacokinetics and Efficacy
- Pharmaceutical and Antibiotic Environmental Impacts
- Patient Satisfaction in Healthcare
- Pediatric Urology and Nephrology Studies
- Cancer-related Molecular Pathways
- Infective Endocarditis Diagnosis and Management
- Kidney Stones and Urolithiasis Treatments
Post Graduate Institute of Medical Education and Research
2016-2025
Institute of Post Graduate Medical Education and Research
2006-2024
Logan Hospital
2024
Robert Bosch (Germany)
2023
Sultan Qaboos University
2021
Chandigarh University
2019
All India Institute of Medical Sciences
1981-2018
Institute of Aviation Medicine
2009
University of Chicago
2002-2005
University of Michigan
1999-2004
Based on the role of phosphorylation histone H2A variant H2AX in recruitment DNA repair and checkpoint proteins to sites damage, we have investigated γH2AX as a reporter tumor radiosensitivity potential target enhance effectiveness radiation therapy. Clinically relevant ionizing (IR) doses induced similar patterns focus formation or immunoreactivity radiosensitive radioresistant human cell lines xenografted tumors. However, cells xenografts retained for greater duration than These results...
BackgroundHealth-care-associated infections (HAIs) cause significant morbidity and mortality globally, including in low-income middle-income countries (LMICs). Networks of hospitals implementing standardised HAI surveillance can provide valuable data on burden, identify monitor prevention gaps. Hospitals many LMICs use case definitions developed for higher-resourced settings, which require human resources laboratory imaging tests that are often not available.MethodsA network 26...
The cellular response to ionizing radiation includes induction of the early growth 1 gene (EGR1). present work has examined involvement reactive oxygen intermediates (ROIs) in this response. Exposure human HL-525 cells, an HL-60 subclone deficient protein kinase C-mediated signaling, both and H2O2 was associated with increases EGR-1 transcripts. These expression were inhibited by antioxidant N-acetyl-L-cysteine (NAC). Nuclear run-on assays demonstrate that NAC inhibits activation EGR1...
Shigella species represent one of the growing numbers antimicrobial-resistant bacteria in developing countries. Fluoroquinolone-resistant strains dysenteriae type 1 and flexneri 2a emerged India during 2002 2003, respectively. Sixty from different parts were analysed for antimicrobial susceptibility, presence qnr plasmid, mutations quinolone resistance determining regions (QRDRs), fluoroquinolone accumulation, other genes encoding to various antimicrobials. had gyrA parC an active efflux...
To determine the pattern and antimicrobial resistance genes of cephalosporin in Shigella flexneri dysenteriae over 9 years. Isolates (S. flexneri, n = 119 S. dysenteriae, 24) were tested for to ceftriaxone cefepime by disc diffusion, MIC Etest extended-spectrum β-lactamase (ESBL) AmpC production. The presence was investigated PCR using specific primers blaTEM, blaOXA-1, blaCTX-M-15, blaSHV blaCMY-2 all isolates. Twenty (16.8%) isolates resistant/intermediately susceptible...
The emergence and spread of antimicrobial resistance (AMR) pose a major threat to the effective treatment control typhoid fever. ongoing outbreak extensively drug-resistant Salmonella Typhi (S. Typhi) in Pakistan has left azithromycin as only remaining broadly efficacious oral for South Asia. Ominously, azithromycin-resistant S. organisms have been subsequently reported Bangladesh, Pakistan, Nepal.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCoinduction of c-jun gene expression and internucleosomal DNA fragmentation by ionizing radiationY. Manome, R. Datta, N. Taneja, T. Shafman, E. Bump, Hass, Weichselbaum, D. KufeCite this: Biochemistry 1993, 32, 40, 10607–10613Publication Date (Print):October 12, 1993Publication History Published online1 May 2002Published inissue 12 October 1993https://pubs.acs.org/doi/10.1021/bi00091a010https://doi.org/10.1021/bi00091a010research-articleACS...
Knowledge of local antibiotic susceptibility rates is essential to strengthen antimicrobial stewardship programs. DASH Protect Antibiotics (https://dashuti.com/), promotes the dissemination focused antibiograms in community urinary tract infection (UTI). This study mapped profile Klebsiella pneumoniae from 18 Indian centers. The centers spanned nine States and three Union Territories. Urinary K. outpatient clinic were collated analyzed. Standardization was achieved through online training....
Antibiotic resistance (AMR) is a significant worldwide health problem, with inappropriate antibiotic prescription being major contributing factor. Prudent use essential for enhancing outcomes and reducing AMR. This study assesses prescribing practices their logic in public community facility catering to 12,900 urban rural populations North India. Cross-sectional research was performed from August 2021 2022, examining 1,219 outpatient prescriptions. The data encompassed medication kind, dose,...
The prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs) has been shown to exert a chemopreventive effect in esophageal and other gastrointestinal tumors. precise mechanism by which this occurs, however, is unknown. While the inhibition COX-2 as potential explanation for gained great deal support, there also exists evidence supporting presence cyclooxygenase-independent pathways through NSAIDs may their effects. In study, immunohistochemical analysis 29 Barrett's epithelial samples...