A5102841965- Urinary Tract Infections Management
- Antibiotic Resistance in Bacteria
- Pediatric Urology and Nephrology Studies
- Urinary Bladder and Prostate Research
- Antimicrobial Resistance in Staphylococcus
- Pneumonia and Respiratory Infections
- Reproductive tract infections research
- Pelvic floor disorders treatments
- Bacterial Identification and Susceptibility Testing
- Antibiotic Use and Resistance
- Viral Infections and Vectors
- Bacterial biofilms and quorum sensing
- Antibiotics Pharmacokinetics and Efficacy
- Leptospirosis research and findings
- Tuberculosis Research and Epidemiology
- Vector-borne infectious diseases
- Surgical site infection prevention
- Bacterial Infections and Vaccines
- Multiple Myeloma Research and Treatments
- Escherichia coli research studies
- Enterobacteriaceae and Cronobacter Research
- Mycobacterium research and diagnosis
- Children's Rights and Participation
- Participatory Visual Research Methods
- COVID-19 and Mental Health
Jawaharlal Nehru Medical College Hospital
2014-2025
Aligarh Muslim University
2016-2025
Dr. Ram Manohar Lohia Institute of Medical Sciences
2025
King George's Medical University
2023-2025
All India Institute of Medical Sciences
2023-2025
All India Institute of Medical Sciences Raipur
2025
All India Institute of Medical Sciences Bhopal
2025
Oxford University Hospitals NHS Trust
2024
University of Reading
2024
University of Cape Town
2024
ABSTRACT Background: Urinary tract infections (UTI) are one of the most common medical complications pregnancy. The emergence drug resistance and particularly Extended-spectrum beta-lactamase production by Escherichia coli methicillin in Staphylococci, limits choice antimicrobials. Materials Methods: Patients different stages pregnancy with or without symptoms urinary infection attending antenatal clinic obstetrics gynaecology were screened for significant bacteriuria, standard loop method...
Global health research typically relies on the translation of knowledge (from professionals to community) and dissemination results wider public). However, Greenhalgh Wieringa [2011. Is it time drop 'knowledge translation' metaphor? A critical literature review. Journal Royal Society Medicine, 104(12), 501–509. doi:10.1258/jrsm.2011.110285] suggest 'that while "translation" is a widely used metaphor in medicine, constrains how we conceptualize study link between practice' (p. 501). Often...
Importance Diabetic retinopathy (DR) is a complication of diabetes that can lead to vision loss. Outcomes continuous glucose monitoring (CGM) and insulin pump use in DR are not well understood. Objective To assess the CGM, pump, or both, proliferative diabetic (PDR) adults with type 1 (T1D). Design, Setting, Participants A retrospective cohort study T1D tertiary center ophthalmology was conducted from 2013 2021, data analysis performed June 2022 April 2023. Exposure Use technologies,...
Introduction: Urinary tract infection (UTI) is one of the most common infectious diseases in clinical practice. The choice antibiotics for treatment UTI limited by rising rates antibiotic resistance. There an urgent need to discover new effective solutions. Fosfomycin may be interesting alternative currently used treatments UTIs. Materials and Methods: study was conducted over 6 months period (January June 2013) Department Microbiology, JNMCH, AMU, Aligarh. A total 1840 urine samples were...
Colistin is a last-resort antibiotic used in extreme cases of multi-drug resistant (MDR) Gram-negative bacterial infections. resistance has increased recent years and often goes undetected due to the inefficiency predominantly standard susceptibility tests (AST). To address this challenge, we aimed detect prevalence colistin strains through both Vitek®2 broth micro-dilution. We investigated 1748 blood, tracheal aspirate, pleural fluid samples from Intensive Care Unit (ICU), Neonatal (NICU),...
Background The rising prevalence of type 2 diabetes mellitus (T2DM) in the elderly is associated with mental health disorders like cognitive impairment and depression due to hyperglycemia inflammation. present study aims estimate its association clinical, biochemical, psychosocial factors identify high-risk subjects. Methods A cross-sectional was conducted at a tertiary care teaching hospital enrolled 99 patients T2DM, aged equal or more than 60 years from North India. Cognitive function...
Background: Mapping the local etiology and antimicrobial susceptibility profile of pathogens causing complicated urinary tract infection (cUTI) is important for promoting evidence based prescribing. WGS plays an role in genomic surveillance AMR understanding circulating clades. Methods: Antimicrobial patients presenting with cUTI were analysed. ESBLs, AmpC β-lactamases, CRE detected by combined disc test (ESBL), D69C detection set (AmpC) KPC/IMP/NDM/VIM/OXA-48 Combo kit (CRE). Whole genome...
Knowledge of local antibiotic susceptibility rates is essential to strengthen antimicrobial stewardship programs. DASH Protect Antibiotics (https://dashuti.com/), promotes the dissemination focused antibiograms in community urinary tract infection (UTI). This study mapped profile Klebsiella pneumoniae from 18 Indian centers. The centers spanned nine States and three Union Territories. Urinary K. outpatient clinic were collated analyzed. Standardization was achieved through online training....
This study examines the evolution of bacterial meningitis etiology and antimicrobial resistance patterns over 20 years at a tertiary care centre in Aligarh, India. Comparing two periods (2001-2009 2015-2021), we identified shift from gram-positive to gram-negative bacteria as primary pathogens, with Staphylococcus aureus decreasing 37.7% 26.6% Klebsiella pneumoniae increasing 4.7% 14.4%. Resistance trends show significant decline effectiveness antibiotics, particularly macrolides,...
Introduction: Urinary tract infection (UTI) continues to be the most common diagnosed in outpatients as well hospitalized patients. Citrobacter spp. is an emerging urinary pathogen. The present study assessed prevalence and antibiotic sensitivity pattern of patients admitted or attending outpatient departments with Complain UTI a tertiary care hospital. Materials Methods: A total 36,250 urine samples were included study. was confirmed 7099 samples. Of these 246 (3.46%) had due Identification...
Evidence-based prescribing is essential to optimise patient outcomes in cystitis. This requires knowledge of local antibiotic resistance rates. DASH Protect Antibiotics (https://dashuti.com/) a multicentric mentorship programme guiding centres preparing, analysing and disseminating antibiograms promote antimicrobial stewardship community UTI. Here we map the susceptibility profile Escherichia coli from 22 Indian centres. These spanned 10 States three Union Territories. Antibiograms for...
Antibiotic-recalcitrant recurrent urinary tract infection (rUTI) is has become increasingly observed in postmenopausal women. Therefore, when standard antibiotic therapies have failed, some elect electrofulguration (EF) of areas chronic cystitis detected on office cystoscopy. EF thought to remove tissue-resident bacteria that been previously the bladder walls women with rUTI. We hypothesized increased bacterial burden may be associated incomplete rUTI resolution following EF.
<br><b>Background:</b> Scrub typhus is lesser known cause of fever unknown origin in India. Even if there have been reports documenting the prevalence scrub different parts India, it still an entity, and clinicians usually do not consider as differential diagnosis. The present study was performed to document among febrile patients western part Uttar Pradesh assess clinical profile infected on one hand knowledge, attitude, practices other. <b>Materials Methods:</b> A total 357 adult with more...
Background: Chronic Suppurative Otitis Media (CSOM) is an important cause of preventable hearing loss. Global emergence resistant strains great concern. The aim the present study was to determine etiology and antibiotic sensitivity pattern bacterial isolates from CSOM cases with special emphasis on ESBL (Extended Spectrum Beta- Lactamases) AmpC beta lactamases.Methods: Patients sign symptoms suggestive CSOM, Beta-Lactamases), lactamases MBLs (Metallo lactamases) were included. Two ear swabs...
Glycosaminoglycans (GAGs) are linear polysaccharides and among the primary components of mucosal surfaces in mammalian systems. The GAG layer lining surface urinary tract is thought to play a critical role homeostasis provide barrier against infection (UTI). This key component host-microbe interface may serve as scaffolding site or nutrient source for microbiota invading pathogens, but its exact UTI pathogenesis unclear. Although members gut have been shown degrade GAGs, utilization...
Urinary tract infection (UTI) is one of the most common adult bacterial infections and exhibits high recurrence rates, especially in postmenopausal women. Studies mouse models suggest that cyclooxygenase-2 (COX-2)–mediated inflammation sensitizes bladder to recurrent UTI (rUTI). However, COX-2–mediated has not been robustly studied human rUTI. We used cohorts assess urothelial COX-2 production evaluate its product, PGE 2 , as a biomarker for rUTI found percentage COX-2–positive cells was...
Purpose: Asymptomatic bacteriuria (ASB) is a common finding during pregnancy. Effective antibiotic treatment could reduce its adverse effects on both mother and fetus. However, emerging antimicrobial resistance limits the options. Fosfomycin might be promising drug in this regard, as still low. The aim of study was to determine susceptibility pattern fosfomycin isolates causing ASB by disc diffusion agar dilution (in selected isolates), minimum inhibitory concentration (MIC) resistant detect...