Sara K. Pasquali

ORCID: 0000-0002-3114-2680
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About
Contact & Profiles
Research Areas
  • Congenital Heart Disease Studies
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac Valve Diseases and Treatments
  • Healthcare Policy and Management
  • Cardiac Structural Anomalies and Repair
  • Aortic Disease and Treatment Approaches
  • Cardiac Arrest and Resuscitation
  • Mechanical Circulatory Support Devices
  • Cardiovascular Issues in Pregnancy
  • Coronary Artery Anomalies
  • Congenital Diaphragmatic Hernia Studies
  • Heart Failure Treatment and Management
  • Tracheal and airway disorders
  • Emergency and Acute Care Studies
  • Infective Endocarditis Diagnosis and Management
  • Hip and Femur Fractures
  • Neonatal Respiratory Health Research
  • Cardiac pacing and defibrillation studies
  • Vascular anomalies and interventions
  • Pharmaceutical studies and practices
  • Child and Adolescent Health
  • Sepsis Diagnosis and Treatment
  • Health Systems, Economic Evaluations, Quality of Life
  • Cardiovascular Function and Risk Factors
  • Trauma and Emergency Care Studies

University of Michigan
2016-2025

C. S. Mott Children's Hospital
2016-2025

English Heritage
2023

Digital Scholar (United States)
2023

Charlottesville Medical Research
2023

New York Proton Center
2023

Scientific Applications & Research Associates (United States)
2011-2022

Cincinnati Children's Hospital Medical Center
2008-2022

Boston Children's Hospital
2008-2020

Society of Thoracic Surgeons
2011-2020

Objective: To empirically derive the optimal measure of pharmacologic cardiovascular support in infants undergoing cardiac surgery with bypass and to assess association between this score clinical outcomes a multi-institutional cohort. Design: Prospective, cohort study. Setting: Cardiac ICUs at four academic children's hospitals participating Pediatric Critical Care Consortium during study period. Patients: Children younger than 1 year time treated postoperatively ICU. Interventions: None....

10.1097/pcc.0000000000000153 article EN Pediatric Critical Care Medicine 2014-04-28

We describe patient characteristics and postoperative morbidity mortality rates for patients with Down syndrome undergoing congenital heart disease surgery.This retrospective cohort study used the Society of Thoracic Surgeons Congenital Heart Surgery Database to compare outcomes (0-18 years) or without who underwent surgery in 2000-2008.A total 45,579 (4350 41,229 syndrome) were included (median age: 7 months [interquartile range [IQR]: 47 days 4 years]; 56% male). Patients younger at...

10.1542/peds.2009-3245 article EN PEDIATRICS 2010-07-13

BACKGROUND AND OBJECTIVE: Prenatal diagnosis allows improved perioperative outcomes for fetuses with certain forms of congenital heart disease (CHD). Variability in prenatal has been demonstrated other countries, leading to efforts improve fetal imaging protocols and access care, but not examined across the United States. The objective was evaluate national variation detection geographic region defect type neonates infants CHD undergoing surgery. METHODS: Cardiovascular operations performed...

10.1542/peds.2014-3783 article EN PEDIATRICS 2015-07-28

Background— In the Single Ventricle Reconstruction (SVR) trial, 1-year transplantation-free survival was better for Norwood procedure with right ventricle–to–pulmonary artery shunt (RVPAS) compared a modified Blalock-Taussig (MBTS). At 3 years, we survival, echocardiographic ventricular ejection fraction, and unplanned interventions in treatment groups. Methods Results— Vital status medical history were ascertained from annual records, death indexes, phone interviews. The cohort included 549...

10.1161/circulationaha.113.006191 article EN Circulation 2014-04-05

OBJECTIVE: Previous analyses have suggested center volume is associated with outcome in children undergoing heart surgery. However, data are limited regarding potential mediating factors, including the relationship of postoperative complications and mortality those who suffer a complication. We examined this association large multicenter cohort. METHODS: Children 0 to 18 years surgery at centers participating Society Thoracic Surgeons Congenital Heart Surgery Database (2006–2009) were...

10.1542/peds.2011-1188 article EN PEDIATRICS 2012-01-10

Background— Gestational age at birth is a potentially important modifiable risk factor in neonates with congenital heart disease. We evaluated the relationship between gestational and outcomes multicenter cohort of undergoing cardiac surgery, focusing on those born early term (ie, 37–38 weeks’ gestation). Methods Results— Neonates Society Thoracic Surgeons Congenital Heart Surgery Database who underwent surgery 2010 2011 were included. Multivariable logistic regression was used to evaluate...

10.1161/circulationaha.113.005864 article EN Circulation 2014-05-03

Outcomes evaluation is enhanced by assignment of operative procedures to appropriate categories based upon relative average risk. Formal risk modelling challenging when a large number operation types exist, including relatively rare procedures. Complexity stratification provides an alternative methodology. We report the initial application in Congenital Heart Surgery Databases Society Thoracic Surgeons (STS) and European Association for Cardio-thoracic (EACTS) empirically derived system...

10.1093/ejcts/ezs026 article EN European Journal of Cardio-Thoracic Surgery 2012-06-14

Abstract Despite many advances in recent years for patients with critical paediatric and congenital cardiac disease, significant variation outcomes remains across hospitals. Collaborative quality improvement has enhanced the value of health care specialties, partly by determining reasons targeting strategies to reduce it. Developing an infrastructure collaborative holds promise developing benchmarks quality, preventable mortality morbidity, optimise long-term cardiovascular unnecessary...

10.1017/s1047951114001450 article EN Cardiology in the Young 2014-08-28

Objectives: In-hospital cardiac arrest occurs in 2.6–6% of children with disease and is associated significant morbidity mortality. Much remains unknown about pediatric ICUs; therefore, we aimed to describe epidemiology a contemporary multicenter ICU cohort. Design: Retrospective analysis within the Pediatric Cardiac Critical Care Consortium clinical registry. Setting: ICUs 23 North American hospitals. Patients: All medical surgical patients admitted from August 2014 July 2016....

10.1097/pcc.0000000000001273 article EN Pediatric Critical Care Medicine 2017-07-21

Several distinct definitions of postoperative death have been used in various quality reporting programs. Some defined mortality as the occurrence after a surgical procedure when patient dies while still hospital, others considered all deaths occurring within predetermined, standardized time interval surgery to be mortality. While data are collected and reported using both these individual definitions, Society Thoracic Surgeons (STS) believes that either approach alone may inadequate....

10.1177/2150135112461924 article EN World Journal for Pediatric and Congenital Heart Surgery 2013-01-01

Children undergoing congenital heart surgery often receive corticosteroids with the aim of reducing inflammatory response after cardiopulmonary bypass; however, value this approach is unclear.

10.1161/circulationaha.110.948737 article EN Circulation 2010-11-09
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