Lawson A. Copley

ORCID: 0000-0002-4325-2414
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About
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Research Areas
  • Orthopedic Infections and Treatments
  • Streptococcal Infections and Treatments
  • Infectious Diseases and Tuberculosis
  • Hematological disorders and diagnostics
  • Antimicrobial Resistance in Staphylococcus
  • Infective Endocarditis Diagnosis and Management
  • Shoulder Injury and Treatment
  • Elbow and Forearm Trauma Treatment
  • Orthopedic Surgery and Rehabilitation
  • Bone fractures and treatments
  • Musculoskeletal Disorders and Rehabilitation
  • Spinal Fractures and Fixation Techniques
  • Bacterial Identification and Susceptibility Testing
  • Knee injuries and reconstruction techniques
  • Immune Response and Inflammation
  • Scoliosis diagnosis and treatment
  • Pneumonia and Respiratory Infections
  • Osteomyelitis and Bone Disorders Research
  • Genetic factors in colorectal cancer
  • Venous Thromboembolism Diagnosis and Management
  • Child and Adolescent Health
  • Genomics and Rare Diseases
  • Bone Tumor Diagnosis and Treatments
  • Sarcoma Diagnosis and Treatment
  • Blood disorders and treatments

Children's Medical Center
2013-2024

The University of Texas Southwestern Medical Center
2015-2024

Texas Scottish Rite Hospital for Children
2013-2024

Southwestern University
2022

Southwestern Medical Center
2008-2018

Scottish Rite Hospital
2014-2017

Vanderbilt University Medical Center
2016

Medical City Children's Hospital
2007-2015

Mayo Clinic in Arizona
2013

Cardinal Glennon Children’s Medical Center
2013

Abstract This clinical practice guideline for the diagnosis and treatment of acute hematogenous osteomyelitis (AHO) in children was developed by a multidisciplinary panel representing Pediatric Infectious Diseases Society (PIDS) America (IDSA). is intended use healthcare professionals who care with AHO, including specialists pediatric infectious diseases, orthopedics, emergency physicians, hospitalists, any clinicians providers caring these patients. The panel’s recommendations AHO are based...

10.1093/jpids/piab027 article EN Journal of the Pediatric Infectious Diseases Society 2021-04-06

Methicillin-resistant Staphylococcus aureus is thought to have led an increase in the incidence of severe musculoskeletal infection children. Our purpose was (1) compare current epidemiology with historical data at same institution 20 years prior and (2) evaluate spectrum severity this disease process within epidemiology.Children infection, treated between January 2002 December 2004, were studied retrospectively. Diagnoses osteomyelitis, septic arthritis, pyomyositis, abscess established for...

10.1097/bpo.0b013e318186eb4b article EN Journal of Pediatric Orthopaedics 2008-10-01

A case-control study.1) To determine if hemodilution adequately meets the transfusion needs in children who undergo posterior spinal fusion for idiopathic scoliosis and 2) to compare efficacy of various methods used reduce risk allogeneic blood at authors' institution.Methods loss avoid caused by extensive surgery adolescents include 1) autologous predonation, controlled hypotensive anesthesia, 3) intraoperative salvage shed (cell saver), 4) acute normovolemic hemodilution, 5) decisions...

10.1097/00007632-199902010-00005 article EN Spine 1999-02-01

Care of children with osteomyelitis requires multidisciplinary collaboration. This study evaluates the impact evidence-based guidelines for treatment pediatric when utilized by a team.Guidelines were developed and implemented team comprised individuals from several hospital services, including orthopaedics, pediatrics, infectious disease, nursing, social work, who met daily to conduct rounds make decisions. With use retrospective review statistical analysis, we compared had been managed at...

10.2106/jbjs.l.00037 article EN Journal of Bone and Joint Surgery 2013-04-01

Severity of illness in children with acute hematogenous osteomyelitis (AHO) is variable, ranging from mild, requiring short-duration antibiotic therapy without surgery, to severe, intensive care, multiple surgeries and prolonged hospitalization. This study evaluates severity among AHO using clinical laboratory findings.Fifty-six AHO, consecutively treated 2009, were retrospectively studied. Objective clinical, radiographic parameters related gathered for each child. A physician panel was...

10.1097/inf.0000000000000002 article EN The Pediatric Infectious Disease Journal 2013-09-04

Summary Between 1988 and 1994, 128 consecutive children with grade III supracondylar humeral fractures presented for treatment at our hospital. Seventeen had absent or diminished (detected Doppler but not palpable) radial pulses on initial examination. Fourteen of these 17 recovered pulse (palpable) after reduction stabilization their fractures. The remaining three persistent absence pulse. Each was explored immediately found to have a significant vascular injury requiring repair. Two the 14...

10.1097/01241398-199601000-00020 article EN Journal of Pediatric Orthopaedics 1996-01-01

The safety of delayed surgical treatment severe supracondylar elbow fractures in children remains debated. No large studies have evaluated complications injury and surgery evaluating only type 3 fractures. Our aim was to review the results our experience treating with at various time points after injury.All treated operatively for humerus from 2004 2007 a single pediatric trauma center were identified. A total 1296 had operative treatment, which 872 Clinical records reviewed identify...

10.1097/bpo.0b013e31829c0046 article EN Journal of Pediatric Orthopaedics 2013-06-28

Background: Radically different conclusions exist in the pediatric orthopaedic and vascular literature regarding management of patients with a pink hand but no palpable radial pulse association supracondylar humeral fracture. Methods: One thousand two hundred ninety-seven consecutive, operatively treated fractures presenting to level-I trauma center from January 2003 through December 2007 were studied retrospectively. Clinical records reviewed determine neurological examination findings,...

10.2106/jbjs.l.01580 article EN Journal of Bone and Joint Surgery 2013-11-06

Culture-negative septic arthritis occurs frequently in children. The supplemental use of polymerase chain reaction (PCR) techniques improves the detection bacteria joint fluid. This study evaluates clinical utility PCR at a tertiary pediatric medical center.Children with were studied prospectively from 2012 to 2014. Culture results and infection parameters recorded. was performed whenever sufficient fluid available aspiration. A statistical comparison made for rates identification causative...

10.1097/bpo.0000000000000411 article EN Journal of Pediatric Orthopaedics 2015-04-17

Culture results affect the diagnosis and treatment of children with musculoskeletal infection. To our knowledge, no previous large-scale study has assessed relative value culture methods employed during evaluation these conditions. The purpose this was to identify an optimal strategy for pediatric infection.Children infection were retrospectively studied assess from site or blood; type, including aerobic, anaerobic, fungal, acid-fast bacteria (AFB); antibiotic exposure history; clinical...

10.2106/jbjs.n.00477 article EN Journal of Bone and Joint Surgery 2015-03-18

This clinical practice guideline for the diagnosis and treatment of acute bacterial arthritis (ABA) in children was developed by a multidisciplinary panel representing Pediatric Infectious Diseases Society (PIDS) America (IDSA). is intended use healthcare professionals who care with ABA, including specialists pediatric infectious diseases orthopedics. The panel's recommendations ABA are based upon evidence derived from topic-specific systematic literature reviews. Summarized below children....

10.1093/jpids/piad089 article EN Journal of the Pediatric Infectious Diseases Society 2023-11-06

An accurate diagnosis of septic versus reactive or autoimmune arthritis remains clinically challenging. A multi-omics strategy comprising metagenomic and proteomic technologies were undertaken for children diagnosed with presumed to advance clinical diagnoses care affected individuals. Twelve suspected prospectively enrolled compare standard tests a rapid approach. The combined bacterial 16S rRNA metagenomics, single cell transcriptomics, proteomics on knee joint fluid specimens. diagnostic...

10.1186/s12969-025-01060-z article EN cc-by-nc-nd Pediatric Rheumatology 2025-01-24

Between 1988 and 1994, 128 consecutive children with grade III supracondylar humeral fractures presented for treatment at our hospital. Seventeen had absent or diminished (detected Doppler but not palpable) radial pulses on initial examination. Fourteen of these 17 recovered pulse (palpable) after reduction stabilization their fractures. The remaining three persistent absence pulse. Each was explored immediately found to have a significant vascular injury requiring repair. Two the 14 who...

10.1097/00004694-199601000-00020 article EN Journal of Pediatric Orthopaedics 1996-01-01

The association of deep venous thrombosis and musculoskeletal infection in children has been reported infrequently. purpose the present study was to evaluate characteristics with osteomyelitis whom developed compare them those did not develop.A retrospective review records who were managed at our institution because a between January 2002 December 2004 identified 212 involving spine, pelvis, or extremities. Children compared it develop respect age, diagnosis, causative organism, duration...

10.2106/jbjs.f.01102 article EN Journal of Bone and Joint Surgery 2007-07-01

Children with osteomyelitis demonstrate a wide spectrum of illness. Objective measurement severity is important to guide resource allocation and treatment decisions, particularly for children advanced The purpose this study validate improve previously published illness scoring system acute hematogenous (AHO).Children AHO were prospectively studied during evaluation by multidisciplinary team who provided care according evidence-based guidelines reduce variation. A score was calculated each...

10.1097/bpo.0000000000000879 article EN Journal of Pediatric Orthopaedics 2016-10-13

Background: Because of the changing referral patterns, operative pediatric supracondylar humerus fractures are increasingly being treated at tertiary centers. To expedite patient flow, type II sometimes pinned in a delayed manner. We sought to determine if delay surgical treatment modified Gartland would affect rate complications following closed reduction and percutaneous pinning. Methods: performed retrospective review consecutive series 399 operatively center over 4 years. Mean age group...

10.1097/bpo.0000000000000124 article EN Journal of Pediatric Orthopaedics 2013-11-22

Supracondylar humerus fractures are the most common operative in children; however, no studies describe older child with this injury. The purpose of study was to compare Gartland type III supracondylar children than 8 years age those younger 8. We hypothesized that there would be more complications children, reflecting a higher-energy injury mechanism.A retrospective chart review managed at single level I pediatric trauma institution from 2004 2007 performed. Patients were divided into...

10.1097/bpo.0b013e31824b542d article EN Journal of Pediatric Orthopaedics 2012-09-01

Meniscus tears in the young patient are becoming more prevalent. Knowledge of presenting characteristics and morphology can affect treatment decisions. The purpose this study was to review evaluate all isolated lateral meniscus pathology that required arthroscopic a pediatric sports medicine practice compare between those with discoid normal meniscal morphology.We performed retrospective procedures from 2003 2012 high-volume practice. Presentation, radiographs, intraoperative findings were...

10.1097/bpo.0000000000000630 article EN Journal of Pediatric Orthopaedics 2015-09-10

Background: Musculoskeletal infections (MSKIs) are a common cause of pediatric hospitalization. Children affected by MSKI have highly variable hospital courses, which seem to depend on infection severity. Early stratification severity would therefore help maximize resource utilization and improve patient care. Currently, MSKIs classified according primary diagnoses such as osteomyelitis, pyomyositis, etc. These diagnoses, however, do not often occur in isolation may differ widely On the...

10.1097/bpo.0000000000000811 article EN Journal of Pediatric Orthopaedics 2016-06-14

Background: The association of deep venous thrombosis and musculoskeletal infection in children has been reported infrequently. purpose the present study was to evaluate characteristics with osteomyelitis whom developed compare them those did not develop. Methods: A retrospective review records who were managed at our institution because a between January 2002 December 2004 identified 212 involving spine, pelvis, or extremities. Children compared it develop respect age, diagnosis, causative...

10.2106/00004623-200707000-00016 article EN Journal of Bone and Joint Surgery 2007-07-01

The changing nature of the United States (US) health care system has prompted debate concerning physician supply. basic questions are: do we have an adequate number surgeons to meet current demands and are training correct future demands? purpose this analysis was characterize pediatric orthopaedic workforce in terms supply demand, both present future.Databases were searched (POSNA, SF Match, KID, MGMA) determine distribution, as well demand.The active Pediatric Orthopaedic Society North...

10.1097/bpo.0000000000000666 article EN Journal of Pediatric Orthopaedics 2015-10-31
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