Bo Zhang

ORCID: 0000-0001-7729-8771
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About
Contact & Profiles
Research Areas
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Systemic Lupus Erythematosus Research
  • Rheumatoid Arthritis Research and Therapies
  • Orthopedic Infections and Treatments
  • Healthcare Operations and Scheduling Optimization
  • Advanced Queuing Theory Analysis
  • Viral Infections and Immunology Research
  • Healthcare Policy and Management
  • AI and Big Data Applications
  • Educational Technology and Assessment

The University of Texas Southwestern Medical Center
2016-2025

Tianjin Normal University
2021

Guangzhou Sport University
2021

Lyft (United States)
2020

Targeted sequencing of sixteen SLE risk loci among 1349 Caucasian cases and controls produced a comprehensive dataset the variations causing susceptibility to systemic lupus erythematosus (SLE). Two independent disease association signals in HLA-D region identified two regulatory regions containing 3562 polymorphisms that modified thirty-seven transcription factor binding sites. These extensive functional are new potent facet HLA polymorphism. Variations modifying consensus motifs IRF4 CTCF...

10.7554/elife.12089 article EN cc-by eLife 2016-02-15

An accurate diagnosis of septic versus reactive or autoimmune arthritis remains clinically challenging. A multi-omics strategy comprising metagenomic and proteomic technologies were undertaken for children diagnosed with presumed to advance clinical diagnoses care affected individuals. Twelve suspected prospectively enrolled compare standard tests a rapid approach. The combined bacterial 16S rRNA metagenomics, single cell transcriptomics, proteomics on knee joint fluid specimens. diagnostic...

10.1186/s12969-025-01060-z article EN cc-by-nc-nd Pediatric Rheumatology 2025-01-24

To better manage patient flows, China has promoted a referral system across the country. Patients are encouraged to receive initial diagnosis in community hospitals (CHs), and general (GHs) slot reservation process fulfill needs of patients, who more severe conditions. According practices, however, policy usually leads either underutilized resources or unsatisfied referrals. This article aims investigate effective method allocating GHs. We formulate as an appointment booking problem,...

10.1109/tase.2019.2962320 article EN IEEE Transactions on Automation Science and Engineering 2020-01-01

<title>Abstract</title> <bold>Objective:</bold> To demonstrate the potential clinical value of multi-omics approach to guide decision-making for children suspected have presumed septic arthritis. <bold>Study design:</bold> Twelve with arthritis were prospectively enrolled conduct standard care culture and polymerase chain reaction (PCR) testing knee joint fluid specimen. A rapid that combines metagenomics host-immune response proteomics single cell transcriptomics synovial was explored...

10.21203/rs.3.rs-4688699/v1 preprint EN cc-by Research Square (Research Square) 2024-08-17

Sports biomechanics refers to the science of laws mechanical motion produced in process biological movement. Its essence is systematically and digitally reconstruct fundamental attributes characteristics motion. At present, research sports mainly focuses on theoretical basic aspects lacks new technology digital simulation innovation data measurement. This article takes badminton chopping action as object carries out biomechanical with help edge computing genetic algorithm. First all, this...

10.1155/2021/5527879 article EN Mobile Information Systems 2021-04-27
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