A5076930255- Salivary Gland Tumors Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Head and Neck Cancer Studies
- Ear and Head Tumors
- Gastroesophageal reflux and treatments
- Cutaneous Melanoma Detection and Management
- Reconstructive Surgery and Microvascular Techniques
- Sarcoma Diagnosis and Treatment
- Adrenal and Paraganglionic Tumors
- Helicobacter pylori-related gastroenterology studies
- Teratomas and Epidermoid Cysts
- Cancer, Hypoxia, and Metabolism
- Nonmelanoma Skin Cancer Studies
- Epilepsy research and treatment
- Thyroid and Parathyroid Surgery
- Pituitary Gland Disorders and Treatments
- Bladder and Urothelial Cancer Treatments
- Bone Tumor Diagnosis and Treatments
- Dysphagia Assessment and Management
- Esophageal Cancer Research and Treatment
- Head and Neck Surgical Oncology
- Tumors and Oncological Cases
- Soft tissue tumors and treatment
- Metastasis and carcinoma case studies
- Genomics and Phylogenetic Studies
Universidade Estadual de Campinas (UNICAMP)
2011-2024
Hospital de Clínicas da Unicamp
2006-2019
Medicina
2000
CONTEXT AND OBJECTIVE: Salivary gland tumor management requires long-term follow-up because of indolence and possible late recurrence distant metastasis. Adenoid cystic carcinoma (ACC) accounts for 10-15% such tumors. The aim here was to evaluate surgical clinical management, staging ACC patients in one academic institution. DESIGN SETTING: Retrospective study at Head Neck Service, Universidade Estadual de Campinas. METHODS: Data on 21 treated between 1993 2003 were reviewed. Management...
CONTEXT: Adenoid cystic carcinomas are malignant tumors that occur in both the major and minor salivary glands. A laryngeal location is rare because of paucity accessory glands this area. account for less than 1% all larynx, only about 120 cases have been reported literature. These a slight female predisposition, their peak incidence fifth sixth decades life. In article, we describe case adenoid carcinoma discuss its clinical characteristics treatment. CASE REPORT: We report on 55 year-old...
CONTEXT AND OBJECTIVE: The use of pedicled myocutaneous flaps in head and neck reconstruction is widely accepted. Here we describe our experience with infrahyoid (IHFs) employed to cover surgical defects the oral cavity oropharynx patients benign malignant tumors. aim was evaluate success rate for flap procedures performed at a single institution. DESIGN SETTING: Retrospective study, Head Neck Surgery Service, Unicamp. METHODS: Fourteen IHFs were used reconstruct eleven men (78.5%) three...
CONTEXT AND OBJECTIVE: Carotid body tumors, or chemodectomas, are the most common head and neck paragangliomas, accounting for 80% of cases. They may present minor symptoms; however, they deserve special attention in order to achieve accurate diagnosis adequate treatment. The objectives this study were show approach towards chemodectomas evaluate complications patients treated surgically without previous embolization.DESIGN SETTING: Retrospective on followed up at Head Neck Surgery Service,...
<p>Carcinoma ex pleomorphic adenoma (CXPA) has been considered an interesting model of carcinogenesis, presenting various histological subtypes and invasiveness phase. The objective was to determine the proliferative index CXPA comparing (PA). Thirty six cases (36 PA) 22 areas PA in (residual were studied by Ki-67 expression. All classified according phase (intracapsular, minimally frankly invasive) histopathological subtypes. Data statistically analyzed Wilcoxon, Mann-Whitney...
To analyze the proteomic profile of salivary pleomorphic adenoma (PA) and carcinoma ex (CXPA) samples correlate them with malignant transformation PA.
A key step of cancer development is the progressive accumulation genomic changes resulting in disruption several biological mechanisms. Carcinoma ex-pleomorphic adenoma (CXPA) an aggressive neoplasm that arises from a pleomorphic adenoma. CXPA derived recurrent PA (RPA) has been rarely reported, and associated with these tumors have not yet studied.We analyzed RPAs without malignant transformation using array-comparative hybridization (array-CGH) to identify somatic copy number alterations...
The aim of this study was to evaluate the use prophylactic oral calcium after total thyroidectomy in prevention symptomatic hypocalcemia, and develop a rational strategy supplementation following type surgery.Prospective including 47 patients undergoing from January 2007 February 2012. were allocated one groups: I (no postoperative calcium) or II (oral 3 g per day). Oral started at first day administered until sixth day. followed up for minimum 6 months evaluated with five measurements...
To investigate the carcinogenic action of hydrochloric acid, pepsin and sodium nitrate on oropharyngeal mucosa rats, simulating reflux gastric contents.Eighty-two Wistar rats were divided in seven groups submitted to 2 or 3 weekly applications pharyngeal during six months. Study comprised 12 animals each. Rats I II (GI) (GII) 0.1N acid. Groups III IV (GIII) (GIV) acid solution with pepsin. V VI (GV) (GVI) treated daily diluted water. Group VII consisted 10 filtered water.No dysplasia,...
CONTEXT: Lingual thyroid gland is a rare clinical entity that caused by the failure of to descend normal cervical location during embryogenesis. The occurrence an ectopic located at base tongue may cause problems for patient, with symptoms dysphagia, dysphonia, upper airway obstruction or even hemorrhage any time from infancy through adulthood. CASE REPORT: We report on case lingual in 41-year-old female patient. embryology and diagnosis are discussed its management outlined. Features...
Objective Tertiary hyperparathyroidism, an autonomous hyperproduction of parathyroid hormone (PTH), has a challenge in its treatment. This study asked whether the intraoperative PTH and calcium drop can confirm resection all tissues. Study Design Case series with planned data collection. Setting referral medical center. Subjects Methods The assessed patients tertiary hyperparathyroidism who were treated at Hospital State University Campinas from 2007 to 2015. All underwent total...
to develop an experimental model of exposure tobacco burning (cigarette) products assess the effects its chronic use in relation cancers bladder.the animals were chronically exposed a semi-open chamber simulate smoking. Thirty young Wistar rats divided into two groups: one with 20 simulating smoking for six months, and ten not control same period. After by inhalation cigarette smoke, euthanized subjected histopathological study bladder wall.no tumor was found but mild non significant...
Context . The possibility of cephalic venous hypertension with the resultant facial edema and elevated cerebrospinal fluid pressure continues to challenge head neck surgeons who perform bilateral radical dissections during simultaneous or staged procedures. Case Report procedure in patients require allows collateral drainage develop, mainly through internal external vertebral plexuses, thereby minimizing risks deleterious consequences. Nevertheless, this has disadvantages, such as a delay...
Polymorphous low-grade adenocarcinoma (PLGA) is a malignant neoplasm of low aggressiveness that occurs almost exclusively in the minor salivary glands, primarily those palate. We report case PLGA arose base tongue and subsequently metastasized to neck. The tumor was resected through oral cavity with wide margins dissection. neck metastasis treated radical dissection radiotherapy. patient recovered remained disease-free at follow-up 30 months later. This shows PLGA, which has variable...
A seven-months-old female child was referred to the head and neck surgery ambulatory due presence of a congenital right mandibular appendicular nodule. The non-consanguineous parents were 23 years-old at birth, after 39 weeks gestation, no adverse events reported. On extraoral physical examination, three centimeters nodule with central ostium, secreting hyaline fluid, observed in cutaneous region, mobile during breastfeeding (Figure 1a). In addition, an asymptomatic ipsilateral four...
O uso crônico da fenitoína ou intoxicação aguda por essa droga produzem lesão cerebelar permanente com atrofia do vermis e hemisférios cerebelares, que pode ser evidenciada através de exames neuroimagem. objetivo deste estudo foi avaliar a correlação entre dosagem o tempo ocorrência cerebelar. Foram realizados levantamento prontuários para obtenção dados clínicos análise tomografias crânio avaliação Dos 66 pacientes estudados, 18 apresentaram moderada severa, 15 leve 33 foram considerados...
To develop experimental models to evaluate the effects of hydrochloric acid associated with pepsin instilled in mucosa upper esophagus and esophagogastric junction young male rats Wistar, simulating injury caused by gastroesophageal reflux on aero-digestive tract humans as well action risk exposure cigarette smoke.Fifty Wistar divided 5 groups 10 animals each one, respectively pharyngo-laryngeal reflux, smoking, smoking only, control group.The histopathologic studies no recorded neoplasias,...
cutaneous melanoma (MC) is a malignant neoplasm derived from melanocytic cells with an aggressive behavior. It usually associated the multifactorial interaction of genetic susceptibility and environmental exposure, ultraviolet radiation. Despite advances in treatment, disease remains relentless poor prognosis. Sentinel lymph node (SLN) biopsy technique used to screen patients need dissection.to correlate tumor burden SLN mortality undergoing biopsy.the medical records histological slides MC...
Abstract Introduction Pleomorphic adenoma (PA) is a benign lesion of the salivary glands that can suffer malignant transformation to carcinoma ex pleomorphic (CXPA). The pathogenesis CXPA has been attributed accumulation genetic disorders in preexisting PAs. However, there no confirmation whether common target gene involved all histopathological subtypes or decisive factors for subtype are specific. Objectives To further analyze genes found PA and using CGH-array technique. were analyzed...