A5085538135- Cellular Mechanics and Interactions
- Hydrogels: synthesis, properties, applications
- Neuroscience and Neuropharmacology Research
- Advanced Materials and Mechanics
- Elasticity and Material Modeling
- Pickering emulsions and particle stabilization
- Protein Structure and Dynamics
- RNA Research and Splicing
- Retinal Development and Disorders
- 3D Printing in Biomedical Research
- Spectroscopy and Quantum Chemical Studies
- Photoreceptor and optogenetics research
- Micro and Nano Robotics
- Force Microscopy Techniques and Applications
- Proteins in Food Systems
- Blood properties and coagulation
- Modular Robots and Swarm Intelligence
- Heat shock proteins research
École Polytechnique Fédérale de Lausanne
2023-2025
Université Paris-Saclay
2024-2025
Laboratoire de Physique Théorique et Modèles Statistiques
2023-2025
Centre National de la Recherche Scientifique
2024
Université Paris-Sud
2023
École Normale Supérieure
2018
École Normale Supérieure - PSL
2018
Université Laval
2005-2006
Gels made of telechelic polymers connected by reversible cross-linkers are a versatile design platform for biocompatible viscoelastic materials. Their linear response to step strain displays fast, near-exponential relaxation when using low-valence cross-linkers, while larger supramolecular bring about much slower dynamics involving wide distribution timescales whose physical origin is still debated. Here, we propose model where the polymer gels in dilute regime originates from elementary...
The activity of Ca 2+ /calmodulin-dependent protein kinase II (CaMKII) plays an integral role in regulating synaptic development and plasticity. We designed a live-cell-imaging approach to monitor activity-dependent clustering green fluorescent (GFP)-CaMKII holoenzymes, termed self-association, process that we hypothesize contributes the translocation CaMKII nonsynaptic sites activated neurons. show GFP-CaMKII self-association human embryonic kidney 293 (HEK293) cells requires catalytic...
One of the hypothesized functions biomolecular condensates is to act as chemical reactors, where reactions can be modulated, i.e., accelerated or slowed down, while substrate molecules enter and products exit from condensate. Similarly, components themselves that take part in architectural integrity might modified by active (energy consuming, non-equilibrium) processes, e.g., ATPase chaperones kinases phosphatases. In this work, we study how presence spatial inhomogeneities, such case...
The self-assembly of particles into organized structures is a key feature living organisms and major engineering challenge. While it may proceed through the binding perfectly matched, puzzle-piece-like particles, many other instances involve ill-fitting that must deform to fit together. These include some pathological proteins, which have known propensity form fibrous aggregates. Despite this observation, general relationship between individual characteristics overall structure aggregate not...
In this study we combine experiments and theoretical modelling to analyse the anisotropic migration response of cells external strain.
One of the hypothesized functions biomolecular condensates is to act as chemical reactors, where reactions can be modulated, i.e. accelerated or slowed down, while substrate molecules enter and products exit from condensate. Likewise, components themselves that take part in architectural integrity might modified by active (energy consuming, non-equilibrium) processes, e.g. ATPase chaperones kinases phosphatases. In this work, we study how presence spatial inhomogeneities, such case...
Gels made of telechelic polymers connected by reversible crosslinkers are a versatile design platform for biocompatible viscoelastic materials. Their linear response to step strain displays fast, near-exponential relaxation when using low valence crosslinkers, while larger supramolecular bring about much slower dynamics involving wide distribution time scales whose physical origin is still debated. Here, we propose model where the polymer gels in dilute regime originates from elementary...
The self-assembly of particles into organized structures is a key feature living organisms and major engineering challenge. While it may proceed through the binding perfectly matched, puzzle-pieces-like particles, many other instances involve ill-fitting that must deform to fit together. These include some pathological proteins, which have known propensity form fibrous aggregates. Despite this observation, general relationship between individual characteristics overall structure aggregate...