Alzheimer's disease (AD) is the most common form of dementia worldwide. The biological mechanisms underlying pathogenesis AD aren't completely clear. Studies have shown that gut microbiota could be associated with pathogenesis; however, pathways involved still need to investigated.To explore possible involvement in through metabolites and identify new biomarkers.Seven-month-old APP/PS1 mice were used as models. Morris water maze test was examine learning memory ability. 16S rRNA gene...

Aqueous halogen batteries are gaining recognition for large-scale energy storage due to their high density, safety, environmental sustainability, and cost-effectiveness. However, the limited electrochemical stability window of aqueous electrolytes absence desirable carbonaceous hosts that facilitate redox reactions have hindered advancement batteries. Here, a low-cost, high-concentration 26 m Li–B5–C15–O6 solution incorporating lithium bromide (LiBr), chloride (LiCl), acetate (LiOAc) was...

The state of charge (SOC) is critical for the safety and reliable utilization battery. However, SOC estimation accuracy lithium iron phosphate (LiFePO4) battery a challenging task because its flat voltage plateau performance affected greatly by temperature. An improved open circuit (OCV) combined with coulomb counting (CC) method based on dual input model ambient temperature OCV proposed. This approach employed to obtain initial value over wide range temperature, establish modified CC...

The primary contributors to elevated line losses in low-voltage distribution networks are three-phase load imbalances and variations peak–valley differentials. conventional manual phase sequence adjustment fails capitalize on the temporal characteristics of load, proliferation smart homes has opened up new scheduling possibilities for managing load. Consequently, this paper introduces a loss-reduction method that leverages load-timing capabilities. This combines dynamic static methods reduce...

The size of precious metal catalysts plays an important role in their activity, and inhibiting aggregation or even sintering is a major challenge practical industrial applications. Herein, the physical limitation fibrous mesoporous silica (KCC-1) Pt–CeO2 interaction CeO2 nanoislands were designed used to inhibit Pt particles, thereby improving intrinsic activity thermal stability. With introduction nanoislands, turnover frequency (TOF) value Pt–CeO2/KCC-1 catalyst for propane-catalyzed...

A low-power process-independent programmable transconductance rail-to-rail operational amplifier (OpAmp) is proposed. It employs an improved feedback loop that senses the (g <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">mT</sub> ) accurately and enforces it to be equal conductance of a reference resistor. Experimental results in 0.13- μm standard CMOS technology under 1-V power supply demonstrate continuous g range from 87 165 μA/V with...

Due to its excellent electrochemical performance, O3-type NaNi 0.33 Fe Mn O 2 (NFM) is one of the most promising cathode materials for sodium ion. However, poor air stability has limited industrialization process. In this work, a low-temperature two-step method which included carbon doping and acid treatment was used improve property air-aged 2. X-ray diffraction results indicated that structure modified NFM (NFM-M) good crystal stability. NFM-M, NFM-48H (NFM after ageing 48 h) fresh...

The LiMn x Fe 1− PO 4 /C ( = 0.5, 0.6, and 0.7) cathode materials for lithium-ion batteries were synthesized by polyethylene glycol (PEG) 400 as the carbon source via a combination of wet ball-milling high-temperature solid-state reaction. analysis results X-ray diffraction (XRD), scanning electron microscopy (SEM), high-resolution transmission (HRTEM) indicate that as-prepared 0.6 0.4 sample has single-phase orthorhombic olivine structure, majority particle sizes range from 100 to 200 nm...

We present a real-time depth based computer vision system for pressure ulcer prevention, in-bed patient care and monitoring. Our can effectively determine whether or not mobility-compromised has been correctly repo-sitioned at the required frequency. A sensor is used to detect recognize movements, motion patterns, pose positions. If stayed in an unchanged too long needs releasing our notify caregivers repositioning assistance. Privacy concerns are mitigated by removing RGB components of...

An ultra-low power analog front end is presented to capture ExG (including ECG, EEG and EMG) signals. It consists of a capacitively coupled chopper instrument amplifier, chopping spike filter VGA. Implemented in standard 0.35μm CMOS technology, this occupying 0.54 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> chip area, while consuming only 3.96μA from 3.3 V supply. Measurement results show an input-referred noise 0.85 μVrms...

A fully integrated 100 kHz X-ray charge coupled device (CCD) readout application specific circuit (ASIC) employing delta sigma ( <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex-math notation="LaTeX">$\Delta \Sigma $</tex-math></inline-formula> ) digitization is presented. To achieve high linearity with small chip size and low power consumption, the correlated double sampling (CDS) realized by notation="LaTeX">$\Sigma \Delta{\rm...

This paper presents the design and implementation of a 14-bit, 100 MS/s CMOS digital-to-analog converter (DAC). Analog background self-calibration based on concept analog current trimming is introduced. A constant clock load switch driver, calibration period randomization circuit return-to-zero output stage have been adopted to improve dynamic performance. The chip has manufactured in SMIC 0.13-μm process occupies 1.33 × 0.97 mm2 core area. consumption 50 mA under 1.2/3.3 V dual power...

This paper presents an energy-efficient reconfigurable 3rd-order continuous-time ΣΔ modulator, which can satisfy multi-band modes for 4G-LTE application. To expand the bandwidth range and optimize energy efficiency, this work employs a flexible architecture, switch between feed-forward feed-back topologies. At circuit level, in order to reduce power consumption, flexibility is also introduced into all core blocks, including amplifiers, multi-bit quantizer feedback DAC. In addition, utilizes...

The presented analog front end (AFE) used to process human bio-signals consists of chopping instrument amplifier (IA), spikes filter and programmable gain bandwidth amplifier. capacitor-coupling input AFE can reject the DC electrode offset. power consumption current-feedback based IA is reduced by adopting capacitor divider in feedback network. Besides, IA's thermal noise decreased utilizing complementary CMOS pairs which offer higher transconductance. Fabricated Global Foundry 0.35 μm...

Travel time, as a fundamental measurement for intelligent transportation systems, is becoming increasingly important. Because of the wide deployment fixed-point detectors on freeways, if travel time can be accurately estimated from point detector data, indirect estimation method cost-effective and widely applicable. This paper presents modified dynamic traffic flow model estimating freeway links under transition congestion conditions with data. The based thorough analysis model. applications...

This paper presents an energy-efficient reconfigurable 3 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">rd</sup> -order continuous-time ΣΔ modulator, which can satisfy multi-band modes for 4G-LTE application. To expand the bandwidth range and optimize energy efficiency, this work employs a flexible architecture, switch between feed-forward feed-back topologies. At circuit level, in order to reduce power consumption, flexibility is also...

A 14-bit 2-GS/s DAC with a high speed programmable interpolation filter in 65nm CMOS Technology is presented. The can be programmed four rate (x1/x2/x8/x16) as test modes for the DAC. It provide data signal to noise ratio (SNR) better than 85dB at 2GHz rate. Segmented structure, thermometer decoder and INL bounded switching sequence techniques are applied improve static performance. Performances frequencies enhanced by using "always on" biasing quad-switch techniques. Complexity reduction...

A high-speed low power decimation filter, as a part of broadband and high resolution sigma-delta A/D converter, is implemented in SMIC 130nm 1P8M CMOS technology. The filter consists comb two half-band filters (HBF). Its consumption reduced by adopting poly-phase decomposition technique, multiplierless architecture hardware reusage. With 500MHz sampling frequency, the achieves signal-to-noise ratio 63.6dB over 20MHz signal bandwidth, while dissipating 4.8mW occupying an area 0.12 mm <sup...