Chandrashekhar Mahakalkar

ORCID: 0000-0002-9969-9725
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Diabetic Foot Ulcer Assessment and Management
  • Periodontal Regeneration and Treatments
  • Peripheral Artery Disease Management
  • Diagnosis and Treatment of Venous Diseases
  • Wound Healing and Treatments
  • Reconstructive Surgery and Microvascular Techniques
  • Central Venous Catheters and Hemodialysis
  • Pelvic and Acetabular Injuries
  • Vascular Procedures and Complications
  • Cardiac, Anesthesia and Surgical Outcomes
  • Gallbladder and Bile Duct Disorders
  • Hernia repair and management
  • Hip and Femur Fractures
  • Streptococcal Infections and Treatments
  • Abdominal Trauma and Injuries
  • Body Contouring and Surgery
  • Sarcoma Diagnosis and Treatment
  • Soft tissue tumor case studies
  • Thyroid and Parathyroid Surgery
  • Antimicrobial Resistance in Staphylococcus
  • Orthopedic Surgery and Rehabilitation
  • Dialysis and Renal Disease Management
  • Gastrointestinal disorders and treatments
  • Thyroid Cancer Diagnosis and Treatment
  • Urinary Tract Infections Management

Datta Meghe Institute of Medical Sciences
2020-2024

Jawaharlal Nehru Medical College
2013-2024

Jawaharlal Nehru Medical College
2020-2024

National Institute for Health Research
2024

University of Birmingham
2024

All India Institute of Medical Sciences
2022

Jawaharlal Nehru Medical College Hospital
2016-2017

Background: The diagnostic utility of Procalcitonin (PCT) and C-Reactive Protein (CRP) as biomarkers for bacterial infection in patients with abdominal sepsis is significant interest due to the critical nature timely accurate diagnosis. Methods: This cross-sectional study included 120 presenting symptoms sepsis. We evaluated sensitivity, specificity, positive predictive value (PPV), negative (NPV) PCT CRP, analyzed their correlation severity Results: mean age subjects was 39.47 years,...

10.52783/jns.v14.2278 article EN Journal of Neonatal Surgery 2025-03-18

Background Gallbladder stones are more common in some regions of the world than others. Gallstones that asymptomatic might be discovered as an afterthought during a regular ultrasound scan for another abdominal ailment. The changing incidence India is mostly due to westernization and availability ultrasonography both urban rural areas, well increased affordability owing changes socio-economic structure budget investigations. This study aims know prevalence gallstone disease risk factors...

10.7759/cureus.24993 article EN Cureus 2022-05-14

Oritavancin is a lipoglycopeptide with bactericidal activity against Gram-positive organisms. Its rapid concentration-dependent and long elimination half-life allow single-dose treatment of acute bacterial skin structure infections (ABSSSI). SOLO I II were randomized, double-blind studies evaluating the efficacy safety single 1,200-mg intravenous (i.v.) dose oritavancin versus twice-daily i.v. vancomycin for 7 to 10 days in ABSSSI patients. Safety data from both pooled analysis. The database...

10.1128/aac.01919-17 article EN Antimicrobial Agents and Chemotherapy 2018-01-18

Background: Lack of appropriate nutritional support during hospitalization may worsen patients’ status and increases risk for infection, organ failure, decreased wound healing suboptimal response to regular medical treatment. The prevalence intensity hospital malnutrition have been recognized as an important parameter in the outcome disease. study aimed at determine incidence hospitalized patients, change nutrition stay its effects on Methods: It was a prospective conducted tertiary care...

10.5455/2320-6012.ijrms20140248 article EN International Journal of Research in Medical Sciences 2014-01-01

Neck lumps can be a symptom of thyroid and parathyroid gland metabolic diseases, papillary carcinoma is reported in some cases. It commonly observed middle-aged people with female predominance. Papillary the most common type cancer, originating from cells. slow-growing less aggressive, but it has been to have ability affect nearby lymph nodes other organs. associated RET protooncogene, NTRK1, MET genes. Early detection crucial, especially for patients. Treatment typically involves...

10.7759/cureus.55627 article EN Cureus 2024-03-06

Mucocele of the appendix is a rare condition caused by mucus accumulation due to blocked resulting from inflammation, infection, or faecal matter blockage. It presents as lower abdominal pain, vomiting, nausea, mass, and distension. more common in individuals over 50 years old prevalent elderly. can be differentiated into mucinous cystadenocarcinoma, mucosal hyperplasia, cystadenoma. often diagnosed incidentally during radiological, laparoscopic, surgical interventions. Ultrasound computed...

10.7860/jcdr/2024/69202.19462 article EN cc-by-nc-nd JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH 2024-01-01

Background: Chronic kidney disease (CKD) is a long term condition caused by damage to both kidneys. The benefits of arteriovenous fistulas over other forms chronic access are: Arteriovenous are associated with decreased morbidity and mortality among hemodialysis patients compared grafts central venous catheters. Objectives the study were o choose proper sites for formation fistula, find out success rate at various complications fistula.Methods: This prospective was carried on total 150...

10.18203/2320-6012.ijrms20164543 article EN International Journal of Research in Medical Sciences 2016-12-19

10.7860/jcdr/2020/43798.13730 article EN cc-by-nc-nd JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH 2020-01-01

BACKGROUNDArterial ulcers are caused by inadequate perfusion of skin and subcutaneous tissues.The key treatment is correcting the underlying medical problem re-perfusion affected tissue.Interventional procedures like angiography, transluminal angioplasty, stenting have hazards bleeding, hematoma formation, false aneurysm formation etc.This study was conducted to investigate effect platelet-rich plasma (PRP) on rate healing peripheral arterial wounds. METHODSA randomized controlled trial with...

10.14260/jemds/2020/486 article EN Journal of Evolution of Medical and Dental Sciences 2020-08-03

Staphylococcus aureus (S. aureus) is a Gram-positive facultative anaerobic bacterium that colonizes the skin and nasal passages of humans. The incidence invasive S. infections has increased over past decades associated with poor outcomes high mortality rates. responsible for almost one-third acute bacterial structure methicillin-resistant (MRSA) accounting large proportion these. strains prevalent inIndia are more aggressive there recent reports emergence virulent multidrug resistant...

10.18203/2349-2902.isj20203821 article EN International Surgery Journal 2020-08-27

Background: Patient satisfaction is an important measure as it a primary means of measuring the effectiveness health-care delivery and success facility. Objective: To evaluate level patients admitted in surgical wards. Materials Method: It was hospital-based cross-sectional questionnaire based study carried out at Acharya Vinoba Bhave Rural Hospital (AVBRH), Sawangi (Meghe), Wardha, Maharashtra, India. The conducted from February 2014 to May among wards AVBRH with minimum hospital stay...

10.5455/ijmsph.2015.13122014135 article EN International Journal of Medical Science and Public Health 2015-01-01

Background: Chronic kidney failure is characterized with progressive and irreversible diminishing of glomerular filtration rate. AVF has been unanimously considered the gold standard vascular access choice for hemodialysis. Arterio-venous fistula (AVF) hemodialysis should be created in patients endogenous creatinine clearance < 20 mL/min/1,73m 2 . Aim current study was to choose proper site arteriovenous creation minimal complications. Methods: It a prospective study, carried out dept....

10.5455/2320-6012.ijrms20140558 article EN International Journal of Research in Medical Sciences 2014-01-01

Background: Foot ulcer is one of the most common and deadest complications diabetes mellitus. This also a frequent cause hospitalization disability. Most patients with diabetic foot ulcers living in developing countries present to healthcare facilities fairly late advanced because poor economic status, inadequate knowledge self-care, sociocultural reasons healthcare.Methods: A prospective study was conducted department Surgery, JNMC Sawangi (Meghe), Wardha DMIMS (DU) aim evaluate pattern...

10.5455/2320-6012.ijrms20150426 article EN International Journal of Research in Medical Sciences 2015-01-01

Necrotizing fasciitis is an illness that ascends quickly and affects the fascia, subcutaneous tissues, deeper skin layers. To combat this infection, strong antibiotics are used along with prompt debridement. Frequent usage of such drugs connected to antibiotic-associated diarrhea colonic illnesses like colitis. High-spectrum antibiotic over extended period time can alter gut microbiota, which promotes growth commensal bacteria including Staphylococcus aureus Clostridioides difficile...

10.7759/cureus.53034 article EN Cureus 2024-01-27

Lipomas are common benign soft tissue tumors composed primarily of mature adipose tissue. They often encountered clinically due to their characteristic slow growth, typically as soft, painless, subcutaneous nodules. While lipomas generally asymptomatic, surgical intervention is sought by patients when they lead discomfort, cosmetic concerns, or functional impairment. In this case report, we present the successful excision 25 in bilateral upper limbs and right thigh a 43-year-old male....

10.7759/cureus.53317 article EN Cureus 2024-01-31

Primary umbilical neoplasms are exceptionally rare. Neurofibromas histologic findings vary from collagenous to myxoid matrix according the neoplastic elements differentiation. We present a case of neurofibroma in supraumbilical region undergoing cystic myxomatous degeneration. A 75-year-old female presented department with complaint swelling above umbilicus for last three years. The was excised and grossly single, irregular, reddish-yellow mass measuring 4.5 × 4 x 3 cm. On cut section,...

10.7759/cureus.54246 article EN Cureus 2024-02-15

An excellent technique for reconstructing the perineum following extensive perineal resection restoration of a traumatised anal sphincter is Gracilis myocutaneous flap. Direct trauma or pelvic injuries can separate sphincters. overlapping sphincteroplasty has fair possibility regaining acceptable fecal continence if roughly half ring still functional. A case 22-year-old male who underwent flap reconstruction after being diagnosed with non functioning reported. free muscle transplant was done...

10.7860/jcdr/2024/68664.19240 article EN cc-by-nc-nd JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH 2024-01-01

Background Peripheral vascular disease (PVD) includes peripheral arterial (PAD) and venous disease. PAD is a chronic progressive atherosclerotic leading to partial or total occlusion. typically affects the abdominal aorta, iliac arteries, lower limbs, occasionally upper extremities. Assessing prevalence of gangrene among PVD patients crucial for understanding burden this condition informing clinical management strategies. This study aimed estimate rate diagnosed with Methods case-control was...

10.7759/cureus.57038 article EN Cureus 2024-03-27

Osteochondromas (OC), or exostoses, are developmental defects rather than true neoplasms. Misdirected physeal bone growths give rise to OC. It causes cartilage-capped bony extensions emerge from the lateral outlines of endochondral bones. We discuss a case OC in 35-year-old female who presented with severe chest wall deformity and breathlessness due compromised left lung function. CT scan showed vast osteochondroma arising ventral surface scapula, which was palpable supra mammary region on...

10.7759/cureus.58275 article EN Cureus 2024-04-14
Coming Soon ...