A5048260390- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Tracheal and airway disorders
- Dysphagia Assessment and Management
- Voice and Speech Disorders
- Head and Neck Cancer Studies
- Tumors and Oncological Cases
- Airway Management and Intubation Techniques
- Lung Cancer Diagnosis and Treatment
- Graphene and Nanomaterials Applications
- Phonetics and Phonology Research
- Prenatal Screening and Diagnostics
- Otolaryngology and Infectious Diseases
- Ocular Oncology and Treatments
- Nasal Surgery and Airway Studies
- Lymphatic System and Diseases
- Ear and Head Tumors
- Boron Compounds in Chemistry
- Cancer Mechanisms and Therapy
- Multiple Myeloma Research and Treatments
- Restraint-Related Deaths
- Nonmelanoma Skin Cancer Studies
- FOXO transcription factor regulation
- Thyroid and Parathyroid Surgery
- Statistical Methods in Clinical Trials
Taipei Tzu Chi Hospital
2010-2025
Tzu Chi University
2008-2025
First Hospital of Jilin University
2025
Jilin University
2025
University of Electronic Science and Technology of China
2024
Buddhist Tzu Chi Medical Foundation
2018
Nanjing Drum Tower Hospital
2016
Stanford University
2015
Stanford Medicine
2015
National Yang Ming Chiao Tung University
2007-2009
To describe the clinical presentations and management of pilomatricoma, formerly known as pilomatrixoma, head neck.Retrospective study.Tertiary care center.The study included 179 patients with a diagnosis pilomatricoma neck.All underwent surgical excision for neck between 1991 2002.Pilomatricoma occurred at any age (mean age, 29.8 years); 45.3% cases in younger than 18 years. The female-male ratio was 0.97:1. average size lesion 1 cm. most common sites occurrence were (30.2%), cheeks...
Objectives/Hypothesis Review drug‐induced sleep endoscopy (DISE) findings and correlate the patterns of airway collapse with body mass index (BMI) objective study respiratory variables, particular emphasis on oxygen desaturation variables. Study Design Retrospective chart review. Methods From January 2010 to March 2014, 64 patients underwent DISE, its were registered using VOTE (velum, oropharynx, tongue base, epiglottis) classification system. Associations analyzed between BMI,...
1q gain/amplification (1q+) is the most common cytogenetic abnormality (CA), with a frequency of 30-50% in patients newly diagnosed multiple myeloma (NDMM). Although accumulating evidence supports 1q+ as "high-risk" CA (HRCA), several issues remain to be addressed understand its true prognostic property. We retrospectively analyzed cohort 934 NDMM from three centers China, who had baseline data available for [including 1q21 gain (3 copies) and amplification (> 3 copies)] detected by...
ABSTRACT Background Recently, graphene oxide (GO) has attracted significant attention as a potential innovative vehicle for the delivery of anticancer agents. In this study, we aimed to evaluate whether functionalized GO, known epithelial cell adhesion molecule (EpCAM)‐targeted polyethylene glycol (PEG)‐coated GO (GO‐PEG‐EpCAM), could be used therapeutic agent against nasopharyngeal carcinoma (NPC) and identify its underlying molecular mechanisms. Methods We NPC cells assess effects...
To evaluate the applicability and effectiveness of percutaneous corticosteroid injection in patients with vocal fold polyp to describe its advantages limitations this group patients.Prospective case series.Tertiary care teaching hospital.Twenty-four treated between March 1 December 31, 2007.Percutaneous performed patient under topical anesthesia. Stroboscopic examination was carried out postoperative response.The Grade Severity Dysphonia, Roughness, Breathiness, Asthenicity, Strain (GRBAS)...
Head and neck cancer patients have a higher risk of developing second primary malignancy (SPM) than the general population. This study was conducted to identify characteristics SPM its impact on survival in with squamous cell carcinoma tongue (TSCC) larynx (LSCC).A retrospective 538 who were treated by surgery primarily for TSCC (n = 146) LSCC 392) from 1990 2000. The incidence, site, overall SPMs evaluated.Seventy-seven developed during follow-up period (median, 73 months), including 18...
This study explored the correlation between clinical explorations, including modified Mallampati score and Müller's maneuver, with drug-induced sleep endoscopy (DISE) findings regarding retrolingual obstruction.One hundred forty-two obstructive apnea patients were enrolled in this prospective study. All of received explorations scoring maneuver clinic. Drug-induced was further evaluated operating room.A significant relationship noted obstruction during DISE. In contrast, no DISE...
To evaluate the role of chest computed tomography (CT) in patients with head and neck squamous cell carcinoma (HNSCC) to determine optimal timing predictive factors for positive findings.Retrospective analysis.Tertiary referral center.Two hundred seventy screening CT scans performed 192 HNSCC during a 42-month period were reviewed.The categorized as new cases, follow-up or recurrent cases. The results classified abnormal normal. Scans having radiologic diagnosis malignant neoplasm lung an...
Introduction: Nasopharyngeal carcinoma (NPC) is a common cancer in southern China and Taiwan, radiation therapy combined with or without chemotherapy its mainstay treatment. Although it highly sensitive to radiotherapy, local recurrence distant metastasis remain difficult unsolved problems. In recent years, graphene oxide (GO) has been found be promising novel anticancer drug carrier. Here, we present our designed functionalized GO, polyethylene glycol-coated GO (GO-PEG), as carrier, which...
Abstract Background This study was conducted to evaluate the relationship between nasal resistance in different posture and optimal positive airway pressure (PAP) level. Other potential factors were also assessed for possible influence on PAP pressure. Methods Forty- three patients diagnosed with obstructive sleep apnea (OSA) prospectively recruited this study. Nasal by active anterior rhinomanometry a seated position then supine at pressures of 75, 150, 300 pascal. The correlating analyzed,...
Objectives/Hypothesis This study aimed to assess the role of capnography in objectively evaluating breathing routes during drug‐induced sleep endoscopy (DISE) and further elucidate relationship between route, obstructive apnea (OSA) severity, DISE findings. Study Design Prospective observational study. Methods Nighty‐five patients with established OSA were recruited for this from May 2017 2019. was performed operating room. Sedation maintained propofol using a target‐controlled infusion...
Abstract Liver fibrosis is an important pathological process in chronic liver disease and cirrhosis. Recent studies have found a close association between intestinal microbiota the development of fibrosis. To determine whether there are differences rhesus macaques with (MG) normal (MN), fecal samples were collected from 8 male MG 12 MN. The biological composition was then detected using 16S rRNA gene sequencing. results revealed statistically significant ASVs Chao1 alpha-diversity...
The aim of this study was to determine the value drug-induced sleep ultrasonography (DISU) for evaluating tongue base thickness (TBT) from awake state sleep, further understand impact dynamic changes in TBT obstructive apnoea (OSA) patients. From May 2017 2018, thirty patients with OSA were prospectively recruited. Sleep induced propofol via use a target-controlled infusion (TCI) system. depth sedation monitored by bispectral (BIS) index BIS levels ranging 50 70. change recorded. correlation...
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The role of podoplanin (PDPN) in nasopharyngeal carcinoma (NPC) is still unknown. aims this study were to investigate the expression and PDPN NPC cells.Immunofluorescence staining functional tests used determine effects knockdown by siRNA TW01 cells. Microarray analysis was conducted identify genes regulated PDPN. molecular mechanism on cells further determined Ingenuity Pathways Analysis (IPA).PDPN expressed most decreased cell proliferation, migration, invasion. microarray data showed 63...
Background The study aimed to evaluate the anatomical differences between positional and non-positional OSA, identify potential predictors for distinguishing these two types of OSA. Methods A cross-sectional 230 consecutive patients with OSA undergoing DISE (Drug-induced Sleep Endoscopy) was carried out at a tertiary academic medical center. factors correlating were analyzed, including clinical characteristics, polysomnography data, findings. Results Univariate analysis revealed that...
Abstract Background Trifluoperazine (TFP) is a typical antipsychotic primarily used to treat schizophrenia. In this study, we aimed evaluate whether TFP can be as therapeutic agent against nasopharyngeal carcinoma (NPC) and identify its underlying molecular mechanisms. Methods We NPC‐TW01, TW03, TW04, BM assess the anticancer effects of by using cytotoxicity, wound healing, colony formation, cell invasion assays. An in vivo animal study was conducted. RNA sequencing combined with Ingenuity...
Lateralizzazione mediante sutura e rilascio aritenoideo per il trattamento dell’immobilità cordale bilaterale con fissazione meccanica.La lateralizzazione al posto dell’ablazione di tessuto endolaringeo via endoscopica è una procedura utilizzata trattare la paralisi fin dal 1980. Tuttavia, meccanica dell’articolazione cricoaritenoidea ha continuamente contrastato l’efficacia della dilatazione glottica, sia nella che nell’ exeresi endolaringeo. Dal 2007 2015, un totale 38 pazienti sono stati...