A5074775823- Multicomponent Synthesis of Heterocycles
- Chemical Synthesis and Reactions
- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Microwave-Assisted Synthesis and Applications
- Synthesis of Indole Derivatives
- Chemical Synthesis and Analysis
- Sulfur-Based Synthesis Techniques
- Synthesis and Characterization of Heterocyclic Compounds
- Electrochemical Analysis and Applications
- Oxidative Organic Chemistry Reactions
- Synthesis and Characterization of Pyrroles
- Inorganic and Organometallic Chemistry
- Synthesis of Organic Compounds
- Cholinesterase and Neurodegenerative Diseases
- Analytical Chemistry and Sensors
- Electrochemical sensors and biosensors
- Ionic liquids properties and applications
- Synthesis of heterocyclic compounds
- Quinazolinone synthesis and applications
- Synthesis and Catalytic Reactions
- X-ray Diffraction in Crystallography
- Polyoxometalates: Synthesis and Applications
- Bioactive Compounds and Antitumor Agents
- Asymmetric Synthesis and Catalysis
Persian Gulf University
2015-2024
Bushehr University of Medical Sciences
2017
Bu-Ali Sina University
2013
University of Birjand
2009-2012
Payame Noor University
2007-2011
Islamic Azad University of Gachsaran
2011
Shiraz University
2003-2009
A catalyst-free one-pot four component methodology for the synthesis of 1,2,4,5-substituted imidazoles under conventional heating and microwave irradiation using 1-butyl-3-methylimidazolium bromide, [Bmim]Br, as a neutral reaction media is described. broad range structurally diverse aldehydes (aromatic bearing electron withdrawing and/or releasing groups well heteroaromatic aldehydes) primary amines aliphatic) were applied successfully, corresponding products obtained in good to excellent...
Sulfuric acid-modified polyethylene glycol 6000 (PEG-OSO3H) is applied as an efficient and eco-friendly polymeric catalyst for Friedländer synthesis of poly-substituted quinolines from 2-aminoaryl ketones (or anthranilonitrile) carbonyl compounds possessing a reactive methylene group under microwave irradiation solvent-free conditions. The reactions are completed in short times, the products obtained good to excellent yields.
In this work, a green, simple and efficient method for the synthesis of 4,4′-(arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)s by condensation 1-phenyl-3-methylpyrazol-5-one with aromatic aldehydes using 1,3-disulfonic acid imidazolium tetrachloroaluminate {[Dsim]AlCl4} as new, heterogeneous reusable catalyst is reported.
An efficient solvent-free procedure for the preparation of bis(indolyl)methanes via condensation indoles with aldehydes as well ketones in presence catalytic amount phosphorus pentoxide/silica gel (P 2 O 5 /SiO ) at room temperature is described.The advantages this method are generality, high yields, short reaction times, ease product isolation, low cost and ecologically friendly.
We report a novel nanostructured organosalt, based on sulfonic acid functionalized pyrazinium {[H-pyrazine–SO3H]Cl2} that was synthesized and characterized by several techniques including Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), thermal gravimetric analysis (TGA), differential (DTG) analysis, transmission electron microscopy (TEM), mass spectrometry (MS), proton NMR (1H NMR), carbon-13 (13C NMR) also (ED) patterns. Results proved the unprecedented sulfonated...
3-Aminopropylated silica gel is introduced as an efficient, reusable, and thermally stable heterogeneous catalyst for tandem Knoevenagel–Michael reaction of 1-phenyl-3-methyl-5-pyrazolone with aldehydes. Short times, mild conditions, ease recovery, reusability make this method a new, economical, waste-free chemical process the efficient synthesis bis(pyrazolyl)methanes.
Abstract The objective of this study was to design new polysubstituted pyrrole derivatives as selective acetylcholinesterase (AChE) inhibitors target Alzheimer's disease. In context, a highly efficient, one-pot, sequential, multi-component synthesis diverse range pyrroles developed through sequential domino strategy by the condensation amines with 1,1-bis(methylthio)-2-nitroethene (BMTNE), Knovenagle reaction arylglyoxals malono and subsequent Michael addition intramolecular cyclization in...
Abstract In this study, a new series of spiro indolin-1,2-diazepine were designed, synthesized, and screened for their cholinesterase inhibitory activities. A novel, green, high-yielding approach was constructed to synthesize derivatives through cascade reaction different isatins, malononitrile 1,1-enediamines (EDAMs) via sequential four-component reactions produce the target compounds with good excellent yields. Next potencies all determined spectroscopically at 415 nm using modified Ellman...
A simple, clean, and highly efficient solvent-free procedure for the preparation of bis(1H-indol-3-yl)methanes is described from reaction carbonyl compounds (aldehydes ketones) with 1H-indole in presence trityl chloride as a catalyst. The proceeds rapidly high yields at room temperature neutral medium. proposed mechanism suggested based upon former reactions calculated results.
Indoles are efficiently condensed with aromatic and aliphatic aldehydes in the absence of any catalyst ionic liquid 1-butyl-3-methylimidazolium bromide {bmim]Br} under microwave irradiation to afford bis(indolyl)methanes good excellent yields short reaction times.
PEG-400 has been used as a green and biodegradable polymeric solvent for the one-pot, two-step, multi-component synthesis of novel asymmetrical bis-spirooxindole derivatives by reaction N-alkyl isatin, isatin derivatives, alkylmalonates C-H activated carbonyl compounds in presence K2CO3 at room temperature. Using this procedure, all products were obtained good to excellent yields.
Abstract Zirconium tetrakis(dodecyl sulfate) [Zr(DS)4] efficiently catalyzes the synthesis of quinoxaline derivatives via condensation 1,2-diamines with 1,2-diketones in H2O as a green media at room temperature. Using this method, title compounds are produced good to excellent yields and relatively short reaction times.