A5100341672- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Angiogenesis and VEGF in Cancer
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Immunotherapy and Biomarkers
- Cancer Mechanisms and Therapy
- Lung Cancer Treatments and Mutations
- Cardiac, Anesthesia and Surgical Outcomes
- Immunotherapy and Immune Responses
- Lung Cancer Research Studies
- Platelet Disorders and Treatments
- Signaling Pathways in Disease
- Oral health in cancer treatment
- Protein Tyrosine Phosphatases
- Atherosclerosis and Cardiovascular Diseases
- Digital Mental Health Interventions
- Antiplatelet Therapy and Cardiovascular Diseases
- FOXO transcription factor regulation
- Intensive Care Unit Cognitive Disorders
- Mobile Health and mHealth Applications
- Nanoplatforms for cancer theranostics
- Endometriosis Research and Treatment
- MRI in cancer diagnosis
- Reproductive System and Pregnancy
- Breast Cancer Treatment Studies
Nantong University
2019-2024
Beijing Institute of Technology
2024
Aerospace Center Hospital
2024
Nantong Tumor Hospital
2019-2024
Songjiang District Central Hospital
2023
GlaxoSmithKline (United States)
2022
Qingdao University
2021
Affiliated Hospital of Qingdao University
2021
Soochow University
2021
First Affiliated Hospital of Soochow University
2021
To evaluate the association between surgical timing and postoperative residual disease status on efficacy of niraparib first-line maintenance therapy in patients with newly diagnosed advanced ovarian cancer at high risk recurrence.Post hoc analysis phase 3 PRIMA/ENGOT-OV26/GOG-3012 (NCT02655016) study primary ovarian, peritoneal, or fallopian tube a complete/partial response to platinum-based chemotherapy. Progression-free survival (PFS) was assessed by (primary debulking surgery [PDS] vs...
Purpose The controlling nutritional status (CONUT) score is a indicator that serves as prognostic factor for many malignancies. This study aimed to investigate the significance of pre-treatment CONUT scores in patients with epithelial ovarian cancer. Methods We evaluated newly diagnosed cancer who were treated at Nantong Tumor Hospital, between January 2013 and April 2016. Pre-treatment calculated using serum albumin levels, total lymphocyte counts, cholesterol levels. optimal cut-off was...
Pretreatment albumin/alkaline phosphatase ratio (AAPR) has been discussed about its prognostic value in several malignancies, whereas role cervical cancer remains unclear. In this study, we attempt to explore the significance of AAPR stage IB-IIA patients who underwent a radical hysterectomy.A total 230 were enrolled retrospective study. The threshold was determined by receiver operating characteristic (ROC) curve. Kaplan-Meier survival analysis and multivariate performed identify...
Background Poor adherence increases the risk of unfavorable outcomes for tuberculosis (TB) patients. Mobile health (mHealth) reminders become promising approaches to support TB patients’ treatment. But their effects on treatment remain controversial. In this prospective cohort study, we evaluated effect reminder application (app) and smart pillbox compared with standard care in Shanghai, China. Methods We recruited new pulmonary (PTB) patients diagnosed between April November 2019 who were...
The neuregulin-1 (NRG-1)/ErbB signaling pathway is a crucial regulator of cardiac development and plays an important role in the formation special conduction system. To establish rat bone marrow stromal cell (BMSC) cardiomyocyte (CM)-like differentiation model, BMSCs were treated with 5-azacytidine fibroblast growth factor basic (FGF-basic) for 24 hours then cocultured neonatal CMs Transwell culture feasibility regulating into sinoatrial node cells by manipulating NRG-1/ErbB was...
Abstract Background To explore the feasibility of adjuvant surgery following concurrent chemoradiation therapy (CCRT) in stage IIB–IIIB (according to FIGO staging 2009) cervical cancer and analyze risk factors recurrence after surgery. Methods Forty-nine patients diagnosed with were reviewed retrospectively. We investigated using Chi-squared Test further analyzed multiple affecting postoperative multi-factor logistic regression. Furthermore, correlation outcomes (including operation time,...
Abstract The forkhead box (FOX) family is a large and diverse group of transcription factors. Forkhead J2 (FOXJ2) member the FOX that aberrantly expressed in variety cancers. However, its role epithelial ovarian cancer (EOC) remains elusive. purpose this study was to evaluate prognostic value FOXJ2 expression patients with cancer. current retrospectively included 151 EOC from January 2013 September 2016. analyzed by immunohistochemistry based on tissue microarrays. Then, clinical outcomes...
Abstract Background To explore the role of GAB2 in pan-cancer based on bioinformatics analysis. Methods Based TCGA and GTEx databases, we used TIMER2.0 online analysis tool R language to analyze expression pan-cancer. We Kaplan–Meier Plotter relationship between OS RFS utilized CPTAC database examine phosphorylated investigated effects mutation features occurrence development human cancers by cBioPortal COSMIC. Using database, conducted an molecular compounds that have potential interact...
To detect the expression of Growth factor binding protein 2 associated (Gab2) and CT10 regulator kinase II (CrkII) in ovarian cancer analyze their clinical significance. explore effects Gab2 CrkII on biological behavior cells. possible molecular mechanism development cancer.Immunohistochemistry was used to cancer. Chi square test correlation between Gab2, parameters. Using Cox regression model evaluate risk factors affecting prognosis. survival rate by Kaplan-Meier. Cell experiments were...