- Advanced biosensing and bioanalysis techniques
- Cancer Treatment and Pharmacology
- SARS-CoV-2 detection and testing
- Biosensors and Analytical Detection
- Chronic Myeloid Leukemia Treatments
- Multiple Myeloma Research and Treatments
- Chronic Lymphocytic Leukemia Research
- Lung Cancer Diagnosis and Treatment
- Blood transfusion and management
- Blood donation and transfusion practices
- Gastrointestinal disorders and treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Abdominal Trauma and Injuries
- Cardiovascular Function and Risk Factors
- Hemoglobinopathies and Related Disorders
- Folate and B Vitamins Research
- Pleural and Pulmonary Diseases
- Sarcoma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Gastrointestinal Tumor Research and Treatment
- Infectious Encephalopathies and Encephalitis
- Advanced X-ray and CT Imaging
- RNA regulation and disease
- Cardiac pacing and defibrillation studies
- Cardiac Structural Anomalies and Repair
Carle Foundation Hospital
2020-2023
Sanjivani Super Speciality Hospitals
2021
Urbana University
2021
New York University
2010
The COVID-19 pandemic has underscored the shortcomings in deployment of state-of-the-art diagnostics platforms. Although several polymerase chain reaction (PCR)-based techniques have been rapidly developed to meet growing testing needs, such often need samples collected through a swab, use RNA extraction kits, and expensive thermocyclers order successfully perform test. Isothermal amplification-based approaches also recently demonstrated for rapid severe acute respiratory syndrome...
Leukoencephalopathy and autonomic dysfunction have been described in individuals with very low serum B<sub>12</sub> levels (<200 pg/ml), addition to psychiatric changes, neuropathy, dementia subacute combined degeneration. Elevated homocysteine methylmalonic acid are considered more sensitive specific for evaluating truly functional deficiency. A previously healthy 62-year-old woman developed depression cognitive deficits that progressed over the course of 5 years. The patient had...
Studies have reported second malignancies occurring in patients with chronic myeloid leukemia (CML) or lymphoid (CLL). We discuss the case of a 77-year-old man diagnosed CLL who later developed CML. The was managed surveillance after diagnosis for 3 years and treated ibrutinib venetoclax. While on treatment venetoclax 4 months, patient had worsening leukocytosis shown via peripheral flow cytometry fluorescence situ hybridization, presence lineage cells positive BCR-ABL complete disappearance...
Abstract The COVID-19 pandemic has underscored the shortcomings in deployment of state-of-the-art diagnostic platforms. Although several PCR-based techniques have been rapidly developed to meet growing testing needs, such often need samples collected through a swab, use RNA extraction kits, and expensive thermocyclers order successfully perform test. Isothermal amplification-based approaches also recently demonstrated for rapid SARS-CoV-2 detection by minimizing sample preparation while...
e20009 Background: Despite expanding therapeutic armamentarium of multiple myeloma (MM), it remains an incurable disease. Therefore, there is a need to assess the impact deeper hematological responses better gauge treatments in clinical trials and routine practice. The presence minimal residual disease (MRD), becoming crucial new standard monitoring remission status. Clinical evidence shows that MRD status after treatment independent prognostic factor for MM. This review summarizes current...
Gastrointestinal stromal tumors (GISTs) are an uncommon malignancy, with origin in the interstitial cells of Cajal located myenteric plexus. The incidence is 5000 new cases every year US. It important to determine genetic alterations GIST. Approximately 90% GISTs have a gain function mutation either c-KIT protooncogene (which encodes for receptor tyrosine kinase KIT) accounting 75%, or platelet derived growth factor alpha (PDGFRA) which accounts 15%. Only 5-10% constitute Wild Type (WT)...
Background: NCCN guidelines for non-small cell lung cancer (NSCLC) establish an evidence-based foundation management of patients with NSCLC.We seek to evaluate the extent surgery undergoing resection NSCLC at a community oncology center.Methods: Retrospective review diagnosis between 01/01/2015 through 12/31/2016 that included any type was done.Data analyzed by IBM SPSS v.20.Results: Total number thoracic 50.Out total 50 patients, 11 (22%) underwent wedge (WDG), 37 (74%) lobectomy (LOB) and...
Introduction: Pacing induced cardiomyopathy (PICM) is defined as a drop in left ventricular ejection fraction (LVEF) due to high amount of right (RV) pacing. Although PICM occurs with chronic, and occasionally, acute burden RV pacing, the minimum pacing inducing not widely established. Hypothesis: Based on multiple cases at our hospital, we hypothesize that >40% would induce PICM. Methods: A single center retrospective analysis was done patients undergoing permanent pacemaker (PPM)...