A5069712930- Dermatology and Skin Diseases
- Allergic Rhinitis and Sensitization
- Systemic Sclerosis and Related Diseases
- Psychosomatic Disorders and Their Treatments
- Dermatologic Treatments and Research
- Asthma and respiratory diseases
- Melanoma and MAPK Pathways
- Cutaneous Melanoma Detection and Management
- Autoimmune and Inflammatory Disorders
- Body Image and Dysmorphia Studies
- Nail Diseases and Treatments
- Complementary and Alternative Medicine Studies
- Mast cells and histamine
- Patient-Provider Communication in Healthcare
- Linguistics and Education Research
- Psoriasis: Treatment and Pathogenesis
- Skin Diseases and Diabetes
- Chromatin Remodeling and Cancer
- Dermatological and COVID-19 studies
- Dermatological and Skeletal Disorders
- Biliary and Gastrointestinal Fistulas
- Families in Therapy and Culture
- Hidradenitis Suppurativa and Treatments
- Sarcoidosis and Beryllium Toxicity Research
- Medical Imaging Techniques and Applications
Ospedale Policlinico San Martino
1996-2025
University of Genoa
1991-2025
Polyclinic Medical Center
2022
Istituti di Ricovero e Cura a Carattere Scientifico
2017
Bambino Gesù Children's Hospital
2013
Sociedad Española de Reumatología
2011
Center for Rheumatology
2004
University of Siena
1997
Several systemic therapies have been approved for the treatment of severe AD. In particular, Janus kinase inhibitors (JAKi), including abrocitinib, baricitinib, and upadacitinib, recently received approval patients with AD after being evaluated in several clinical trials. However, a few concerns raised regarding their long-term safety management these drugs real-world practice. this article we described results Delphi consensus aimed at describing knowledge on JAKi focusing, providing...
Microvascular lesions are a predominant feature in systemic sclerosis (SSc) and seem to play central pathogenetic role. Recently, we graded scleroderma microangiopathy by nailfold videocapillaroscopy (NVC) into three NVC patterns (early, active late). The aim of the present study was confirm, larger number SSc patients, presence microvascular damage, detect any possible relationship between these both specific serum autoantibodies subsets cutaneous involvement.Two hundred forty-one...
Additional data supporting the findings of this manuscript are available on reasonable request to corresponding author.
Mutations in the CDKN2A gene underlie melanoma susceptibility as many 50% of kindreds selected populations, and several founder mutations have been described. Inherited found to be associated with other, non-melanoma cancers including pancreatic cancer (PC) neural system tumors (NST). Here we report a novel germline mutation exon 1 gene, E27X, which first detected patients living or originally from small geographic area bordering Liguria north-western Italy. A subset positive for this...
Psoriasis largely affects daily activities and social interactions has a strong impact on patients' quality of life. Psoriatic patients have different attitudes toward their condition. Topical medications are essential for the treatment psoriasis, but majority do not adhere to these therapies.The history success or failure seems influence patient attitude topical therapy. Therefore, it is important understand psychological, experiential, motivational aspects that could be critical adherence,...
Introduction: Diffuse Melanosis Cutis (DMC) is a rare and late complication of metastatic malignant melanoma (MM) characterized by progressive pigmentation skin sometimes mucous membranes. The distinctive feature the widespread deposition melanin precursors in dermis. Objectives: purpose this review to define clinical demographic features DMC promote deeper insight into manifestation, histological findings, pathophysiology behind DMC. Methods: We have conducted systematic literature on...
Abrocitinib is a JAK-1 inhibitor approved for the treatment of moderate-to-severe atopic dermatitis (AD). We conducted 16-week multicenter retrospective study to assess short-term effectiveness and safety abrocitinib in patients with AD.
Introduction: The aim of the present study was to demonstrate, by nailfold videocapillaroscopy (NVC), existence diagnostic and follow-up parameters microvascular damage in systemic sclerosis (SS) (grouped “early”, “active” “late” NVC patterns). presence different subsets skin involvement (limSS difSS), as well role some specific serum autoantibodies expression were investigated. Methods: 245 consecutive SS patients recruited clinical data assessed. Antinuclear (ANA), antitopoisomerase I...
Sensitive scalp is a common condition defined by the presence of erythema and/or subjective symptoms as pain, pricking, burning, pruritus elicited triggering factors. Trichodynia term that describes sensation pain or burning and was assumed to be part sensitive scalp. Main goal study establish prevalence in patients with trichological disorders. We conducted retrospective observational recorded: age, sex, disorder (telogen effluvium, androgenetic alopecia, alopecia areata, scarring...
We report the case of a 23-year-old woman with an erythematous, crusted patch scalp, lacking pustular lesions, partial hair loss, developed after mechanical scalp trauma. Histopathological examination showed dermal infiltrate, predominantly peri-adnexal and peri-vascular, rich in plasma cells lymphocytes, but neutrophils, possibly as consequence time elapsed since onset skin disease. Reduction functional follicles was evidenced. Stains for bacterial or fungal infections were negative. Direct...