- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Cardiovascular and Diving-Related Complications
- Sleep and Wakefulness Research
- Pediatric health and respiratory diseases
- Pulmonary Hypertension Research and Treatments
- Asthma and respiratory diseases
- Gut microbiota and health
- Long-Term Effects of COVID-19
- Tracheal and airway disorders
- Dysphagia Assessment and Management
- Healthcare cost, quality, practices
- Medical Malpractice and Liability Issues
- Sleep and related disorders
- Space Science and Extraterrestrial Life
- Cardiovascular Disease and Adiposity
- High Altitude and Hypoxia
- Neuroethics, Human Enhancement, Biomedical Innovations
- Temporomandibular Joint Disorders
- Interdisciplinary Studies: Technology, Society, and Humanities
- Healthcare Decision-Making and Restraints
- Inhalation and Respiratory Drug Delivery
- Mesenchymal stem cell research
Ospedale Vito Fazzi
2015-2025
ASL Roma
2025
Regione Puglia
2011-2020
Institutul National Victor Babes
2017
Istituto Nazionale di Fisica Nucleare, Sezione di Lecce
2015
University of Salento
2015
Introduction: Obstructive sleep apnea (OSA) is a serious and prevalent medical condition with major consequences for health safety. Excessive daytime sleepiness (EDS) common –but not universal- accompanying symptom. The purpose of this literature analysis to understand whether the presence/absence EDS associated different physiopathologic, prognostic therapeutic outcomes in OSA patients. Methods: Articles English published PubMed, Medline, EMBASE between January 2000 June 2017, focusing on...
OSA is a heterogeneous disease with variable physio-pathological and clinical manifestations, it associated numerous co-morbidities (1). It chronic inflammatory low degree of activity (2), in which the microbiome now widely considered to play role. In last few decades, research into has rapidly evolved become hot topic basic research, both pre-clinical clinical. Some recent studies have demonstrated that gut microbiota (GM), situated human gastrointestinal tract consisting bacteria, viruses,...
For many years until now, Italy has been subjected to an inconsistent and contradictory media campaign. On one hand the "media" present us with bold reassuring messages about progress of medical science; on other they are prone kneejerk criticism every time treatment does not have desired effect, routinely describing such cases as glaring examples "malasanità", Italian word recent coinage used denote malpractice. Newspaper reports legal proceedings involving health frequently full errors...
Patients with obstructive sleep apnea (OSA) suffer from several neurocognitive disturbances. One of the neuropsychological processes most investigated in OSA patients is attention, but results have been controversial. Here, we update attention profile final aim to improve assessment, a possible impact on clinical and medical-legal practices, terms which subdomains parameters need consideration one high-risk phenotype for dysfunctions.For this purpose, assessed 32 previously untreated (26 men...
Introduction: Patients with obstructive sleep apnea (OSA) suffer from several neurocognitive deficits. We investigated the cognitive and socio-cognitive profiles of patients severe OSA, controlling for potentially relevant mediating variables (i.e. age, body-mass index, reserve depression). Moreover, we studied neuropsychological profile a high-risk OSA phenotype characterized by nocturnal hypoxemia.Method: assessed 29 previously untreated mean age 55.6 (± 9.9 years) apnea-hypopnea index...
Background COVID-19 pandemic resulted in about 165 million infections and 3.4 deaths all over the world across 15 months. The most severe clinical presentation of diseases is interstitial pneumonia. Methods In this paper we describe outcomes based on radiological features as well pattern haematochemical parameters IgG/IgM antibodies 75 patients hospitalized due to COVID-related pneumonia not requiring intensive care assistance. Each patient underwent routine laboratory tests, including...
Background: For many years until now, Italy has been subjected to an inconsistent and contradictory media campaign. On one hand the “media” present us with bold reassuring messages about progress of medical science; on other they are prone kneejerk criticism every time treatment does not have desired effect, routinely describing such cases as glaring examples “malasanità”, Italian word recent coinage used denote malpractice. Newspaper reports legal proceedings involving health frequently...
Obstructive sleep apnea (OSA) syndrome is a condition characterized by the presence of repeated complete or partial collapse upper airways during associated with episodes intermittent hypoxia, leading to fragmentation sleep, sympathetic nervous system activation, and oxidative stress. To date, one major aims research find out simplified non-invasive screening for this still underdiagnosed disease. The Berlin questionnaire (BQ) most widely used OSA beneficial tool devised select subjects high...
Chronic obstructive pulmonary disease (COPD) is a significant and rising global health problem.It complex with genetic, epigenetic, environmental influences characterized by progressive airflow limitation, chronic inflammation in the lungs, associated systemic inflammation.No effective cure for COPD exists to date research into new therapies will be essential if this managed future.Obesity metabolic syndrome malnutrition represent two poles of abnormalities that may relate inflammation.The...
The gold standard for the diagnosis of Obstructive Sleep Apnea (OSA) is polysomnography, whose access however reduced by costs and limited availability, so that additional diagnostic tests are needed.To analyze accuracy Airway Adult Test (OAAT) compared to polysomnography OSA in adult patients.Ninety patients affected verified with (AHI ≥ 5) ten healthy patients, randomly selected, were included all interviewed one blind examiner OAAT questions.The Spearman rho, evaluated measure correlation...
To illustrate a new technological advance in the standard drug-induced sleep endoscopy (DISE) model, machine was used, Experimental 5 Video Stream System (5VsEs), which is capable of simultaneously visualizing all decisional parameters on single monitor, and recording storing them uneditable video. The DISE procedure performed 48 obstructive apnea (OSA) or snoring patients. recorded monitor are (1) pharmacokinetics pharmacodynamics propofol (through target controlled infusion (TCI) pump...