Domenico Maurizio Toraldo

ORCID: 0000-0003-0023-0212
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About
Contact & Profiles
Research Areas
  • Obstructive Sleep Apnea Research
  • Neuroscience of respiration and sleep
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Respiratory Support and Mechanisms
  • Cardiovascular and Diving-Related Complications
  • Sleep and Wakefulness Research
  • Pediatric health and respiratory diseases
  • Pulmonary Hypertension Research and Treatments
  • Asthma and respiratory diseases
  • Gut microbiota and health
  • Long-Term Effects of COVID-19
  • Tracheal and airway disorders
  • Dysphagia Assessment and Management
  • Healthcare cost, quality, practices
  • Medical Malpractice and Liability Issues
  • Sleep and related disorders
  • Space Science and Extraterrestrial Life
  • Cardiovascular Disease and Adiposity
  • High Altitude and Hypoxia
  • Neuroethics, Human Enhancement, Biomedical Innovations
  • Temporomandibular Joint Disorders
  • Interdisciplinary Studies: Technology, Society, and Humanities
  • Healthcare Decision-Making and Restraints
  • Inhalation and Respiratory Drug Delivery
  • Mesenchymal stem cell research

Ospedale Vito Fazzi
2015-2025

ASL Roma
2025

Regione Puglia
2011-2020

Institutul National Victor Babes
2017

Istituto Nazionale di Fisica Nucleare, Sezione di Lecce
2015

University of Salento
2015

Introduction: Obstructive sleep apnea (OSA) is a serious and prevalent medical condition with major consequences for health safety. Excessive daytime sleepiness (EDS) common –but not universal- accompanying symptom. The purpose of this literature analysis to understand whether the presence/absence EDS associated different physiopathologic, prognostic therapeutic outcomes in OSA patients. Methods: Articles English published PubMed, Medline, EMBASE between January 2000 June 2017, focusing on...

10.3389/fneur.2018.00505 article EN cc-by Frontiers in Neurology 2018-06-27

OSA is a heterogeneous disease with variable physio-pathological and clinical manifestations, it associated numerous co-morbidities (1). It chronic inflammatory low degree of activity (2), in which the microbiome now widely considered to play role. In last few decades, research into has rapidly evolved become hot topic basic research, both pre-clinical clinical. Some recent studies have demonstrated that gut microbiota (GM), situated human gastrointestinal tract consisting bacteria, viruses,...

10.3389/fncel.2024.1429570 article EN cc-by Frontiers in Cellular Neuroscience 2025-01-06

For many years until now, Italy has been subjected to an inconsistent and contradictory media campaign. On one hand the "media" present us with bold reassuring messages about progress of medical science; on other they are prone kneejerk criticism every time treatment does not have desired effect, routinely describing such cases as glaring examples "malasanità", Italian word recent coinage used denote malpractice. Newspaper reports legal proceedings involving health frequently full errors...

10.1186/s40248-015-0006-3 article EN cc-by-nc Multidisciplinary Respiratory Medicine 2015-03-26

Patients with obstructive sleep apnea (OSA) suffer from several neurocognitive disturbances. One of the neuropsychological processes most investigated in OSA patients is attention, but results have been controversial. Here, we update attention profile final aim to improve assessment, a possible impact on clinical and medical-legal practices, terms which subdomains parameters need consideration one high-risk phenotype for dysfunctions.For this purpose, assessed 32 previously untreated (26 men...

10.3390/brainsci10060325 article EN cc-by Brain Sciences 2020-05-27

Introduction: Patients with obstructive sleep apnea (OSA) suffer from several neurocognitive deficits. We investigated the cognitive and socio-cognitive profiles of patients severe OSA, controlling for potentially relevant mediating variables (i.e. age, body-mass index, reserve depression). Moreover, we studied neuropsychological profile a high-risk OSA phenotype characterized by nocturnal hypoxemia.Method: assessed 29 previously untreated mean age 55.6 (± 9.9 years) apnea-hypopnea index...

10.1080/13803395.2021.1944609 article EN Journal of Clinical and Experimental Neuropsychology 2021-05-28

Background COVID-19 pandemic resulted in about 165 million infections and 3.4 deaths all over the world across 15 months. The most severe clinical presentation of diseases is interstitial pneumonia. Methods In this paper we describe outcomes based on radiological features as well pattern haematochemical parameters IgG/IgM antibodies 75 patients hospitalized due to COVID-related pneumonia not requiring intensive care assistance. Each patient underwent routine laboratory tests, including...

10.1371/journal.pone.0262911 article EN cc-by PLoS ONE 2022-02-22

Background: For many years until now, Italy has been subjected to an inconsistent and contradictory media campaign. On one hand the “media” present us with bold reassuring messages about progress of medical science; on other they are prone kneejerk criticism every time treatment does not have desired effect, routinely describing such cases as glaring examples “malasanità”, Italian word recent coinage used denote malpractice. Newspaper reports legal proceedings involving health frequently...

10.4081/mrm.2015.285 article EN cc-by-nc Multidisciplinary Respiratory Medicine 2015-03-26

Obstructive sleep apnea (OSA) syndrome is a condition characterized by the presence of repeated complete or partial collapse upper airways during associated with episodes intermittent hypoxia, leading to fragmentation sleep, sympathetic nervous system activation, and oxidative stress. To date, one major aims research find out simplified non-invasive screening for this still underdiagnosed disease. The Berlin questionnaire (BQ) most widely used OSA beneficial tool devised select subjects high...

10.3389/fmed.2022.866822 article EN cc-by Frontiers in Medicine 2022-05-25

Chronic obstructive pulmonary disease (COPD) is a significant and rising global health problem.It complex with genetic, epigenetic, environmental influences characterized by progressive airflow limitation, chronic inflammation in the lungs, associated systemic inflammation.No effective cure for COPD exists to date research into new therapies will be essential if this managed future.Obesity metabolic syndrome malnutrition represent two poles of abnormalities that may relate inflammation.The...

10.4172/2155-6121.s2-005 article EN Journal of Allergy & Therapy 2011-01-01

The gold standard for the diagnosis of Obstructive Sleep Apnea (OSA) is polysomnography, whose access however reduced by costs and limited availability, so that additional diagnostic tests are needed.To analyze accuracy Airway Adult Test (OAAT) compared to polysomnography OSA in adult patients.Ninety patients affected verified with (AHI ≥ 5) ten healthy patients, randomly selected, were included all interviewed one blind examiner OAAT questions.The Spearman rho, evaluated measure correlation...

10.1155/2015/915185 article EN cc-by BioMed Research International 2015-01-01

To illustrate a new technological advance in the standard drug-induced sleep endoscopy (DISE) model, machine was used, Experimental 5 Video Stream System (5VsEs), which is capable of simultaneously visualizing all decisional parameters on single monitor, and recording storing them uneditable video. The DISE procedure performed 48 obstructive apnea (OSA) or snoring patients. recorded monitor are (1) pharmacokinetics pharmacodynamics propofol (through target controlled infusion (TCI) pump...

10.3390/ijerph17124261 article EN International Journal of Environmental Research and Public Health 2020-06-15
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