A5009471084- Congenital Heart Disease Studies
- Pulmonary Hypertension Research and Treatments
- Mechanical Circulatory Support Devices
- Cardiac Arrhythmias and Treatments
- Congenital Diaphragmatic Hernia Studies
- Cardiovascular Issues in Pregnancy
- Cardiac Valve Diseases and Treatments
- Ultrasound in Clinical Applications
- Aortic Disease and Treatment Approaches
- Tracheal and airway disorders
- Cardiac Structural Anomalies and Repair
- Cardiac tumors and thrombi
- Neonatal Respiratory Health Research
- Coronary Artery Anomalies
- Cardiac, Anesthesia and Surgical Outcomes
- Diversity and Career in Medicine
- Central Venous Catheters and Hemodialysis
- Hemodynamic Monitoring and Therapy
- Vascular anomalies and interventions
- Cardiovascular Conditions and Treatments
- Wildlife Ecology and Conservation
- Cardiac Arrest and Resuscitation
- Health and Medical Research Impacts
- Pleural and Pulmonary Diseases
- Vascular Anomalies and Treatments
Children's Hospital of Philadelphia
2023-2025
University of Pennsylvania
2023-2025
Philadelphia University
2023-2025
Boston Children's Hospital
2014-2024
Boston Children's Museum
2014-2024
Harvard University
2015-2023
Brigham and Women's Hospital
2022
Georgetown University
2021
Institute of Cardiology
2021
Yale University
2019
Background: Fetal aortic valvuloplasty (FAV) may prevent progression of midgestation stenosis to hypoplastic left heart syndrome. However, FAV has well-established risks, and its survival benefit remains unknown. Our primary aim was determine whether for increases from fetal diagnosis age 6 years. Methods Results: We performed a retrospective analysis 143 fetuses who underwent 2000 2017 secondary the Pediatric Heart Network Single Ventricle Reconstruction trial. Using these results, we...
ABSTRACT Background and Aims Drug‐eluting stents (DES) are not designed for overexpansion to supra‐nominal diameters or intentional stent fracture (ISF). The optimal dilation technique minimize shortening (SS) achieve ISF accommodate pediatric somatic growth has been described. Methods Three sizes of two commonly used DES were implanted within a silicone model simulate blood vessels. Each was serially dilated in 1 mm increments under fluoroscopy using three techniques: 2 cm length,...
Development of postoperative obstruction in total anomalous pulmonary venous connection (TAPVC) is a major cause morbidity and mortality. Although preoperative echocardiography has often been cited as prognostic outcome, its predictive value not fully evaluated. Pulmonary variability index (PVVI) an echocardiographic metric developed at our center previously shown to correlate with clinical markers catheterization findings obstruction. We hypothesized that PVVI would be superior maximum mean...
Background: Assessing left ventricular (LV) preparedness in congenitally-corrected transposition of the great arteries/intact septum (ccTGA/IVS) prior to double switch operation (DSO) remains challenging. Subpulmonary LV Pressure-Volume Area (PVA) - a comprehensive metric workload when compared systemic right (RV) PVA as benchmark, may be good index adequacy. Aims: Determine (1) if can estimated from simple catheterization and imaging parameters, using conductance-catheter derived reference,...
Restenosis in pediatric pulmonary vein stenosis (PVS) is common and requires careful monitoring. Lung perfusion scintigraphy (LPS) often used but involves excess radiation, resource-intensive, can cause patient discomfort, with no real-time data available. This study evaluated the fluoroscopic flow calculator (FFC) as a tool for estimating blood (Qp) using angiograms during catheterization, potential to replace or complement LPS. A retrospective cross-sectional was conducted on patients PVS...
To assess the variation in timing of left atrial decompression and its association with clinical outcomes pediatric patients supported venoarterial extracorporeal membrane oxygenation across a multicenter cohort.Multicenter retrospective study.Eleven hospitals within United States.Patients less than 18 years on who underwent from 2004 to 2016.None.A total 137 (median age, 4.7 yr) were included. Cardiomyopathy was most common diagnosis (47%). Cardiac arrest (39%) low cardiac output (50%)...
We conducted a study to determine whether patients born with Trisomy 21 and left-to-right shunts who develop pulmonary vein stenosis (PVS) have longer exposure shunt physiology compared those do not PVS. included seen at Boston Children’s Hospital between 15 August 2006 31 2017 developed PVS within 24 months of age. retrospective 3:1 matched case–control study. The primary predictor was length as defined date birth the first echocardiogram showing mild or no shunt. Case were more likely than...
Pulmonary vein stenosis is a serious condition characterized by restriction or blockage due to fibrotic tissue ingrowth that develops in the pulmonary veins of infants children. It often progressive and can lead severe hypertension death. Efforts halt reverse disease progression include surgery catheter-based balloon dilation stent implantation. Its cause mechanism are unknown. In this pilot study, we propose explore hypothesis elevated wall shear stress at discrete venous sites triggers...
In human pregnancy, recognition of an embryo within the uterus is essential to support fetus through gestation. most marsupials, such as opossums, pregnancy shorter than oestrous cycle and steroid hormone profile during are indistinguishable. For these reasons, it was assumed that a trait, evolved in eutherian (placental) stem lineage independently wallabies kangaroos. To investigate whether uterine occurs species with cycle, we examined reproduction short-tailed opossum ( Monodelphis...