Najibullah Safi

ORCID: 0000-0003-0042-7007
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About
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Research Areas
  • Healthcare Systems and Reforms
  • Global Maternal and Child Health
  • Malaria Research and Control
  • Health and Conflict Studies
  • Viral gastroenteritis research and epidemiology
  • Global Public Health Policies and Epidemiology
  • Politics and Conflicts in Afghanistan, Pakistan, and Middle East
  • Computational Drug Discovery Methods
  • Global Health Care Issues
  • Mosquito-borne diseases and control
  • Hepatitis B Virus Studies
  • Animal Virus Infections Studies
  • Hepatitis Viruses Studies and Epidemiology
  • Legal, Health, Environmental and COVID-19 Challenges
  • Viral Infections and Vectors
  • Research on Leishmaniasis Studies
  • Semantic Web and Ontologies
  • Travel-related health issues
  • Global Security and Public Health
  • COVID-19 and healthcare impacts
  • Global Health Workforce Issues
  • Vector-borne infectious diseases
  • Drug Transport and Resistance Mechanisms
  • Vaccine Coverage and Hesitancy
  • Gastrointestinal disorders and treatments

World Health Organization - Afghanistan
2012-2025

World Health Organization - Zimbabwe
2025

World Health Organization - Pakistan
2020-2024

University of Suffolk
2022

King Saud University
2015-2019

Ministry of Public Health
2009-2018

Abstract Background Malaria is a significant public health concern in Afghanistan. Currently, approximately 60% of the population, or nearly 14 million people, live malaria-endemic area. Afghanistan's diverse landscape and terrain contributes to heterogeneous malaria prevalence across country. Understanding role environmental variables on transmission can further effort for control programme. Methods Provincial epidemiological data (2004-2007) collected by posts 23 provinces were used...

10.1186/1475-2875-9-125 article EN cc-by Malaria Journal 2010-05-13

Anthroponotic cutaneous leishmaniasis (CL) is a common cause of ulcerative lesions and disfiguring scarring among children in Afghanistan. Most occur on the face are commonly caused by trypanosome protozoan parasite Leishmania tropica, transmitted bite an infected sandfly (Phlebotomus sergenti). This study compared effectiveness single localized treatment with thermotherapy to 5 days intralesional administration Glucantime for CL. Three hundred eighty-two patients CL were randomly assigned...

10.7205/milmed-d-11-00161 article EN Military Medicine 2012-03-01

Abstract Background Afghanistan is suffering from a triple burden of diseases. One every two Afghan dying due to non-communicable diseases (NCDs). The national health account report shows that people are paying 77% expenditure their pocket especially for diagnostic and treatment purposes. Considering the huge number mortality related NCDs, this paper aimed analyze financing system NCDs provide recommendations policy makers program managers in international institutions. Methods A qualitative...

10.1186/s12939-025-02423-4 article EN cc-by International Journal for Equity in Health 2025-04-09

Despite progress in recent years, Afghanistan is lagging behind realizing the full potential of immunization. The country still endemic for polio transmission and measles outbreaks continue to occur. In spite significant reductions over past decade, mortality rate children under 5 years age continues remain high at 91 per 1000 live births.The study was a descriptive community-based cross sectional household survey. survey aimed estimate levels immunization coverage national province levels....

10.1186/s12889-017-4193-z article EN cc-by BMC Public Health 2017-04-04

Afghanistan is suffering from 40-year chronic conflicts, displacement, and demolition of its infrastructure. mortality survey 2010 shows nearly 46% all deaths in the country were attributed to noncommunicable diseases (NCDs). In this study, we aimed understand differences premature death due NCDs by sex trend for next 8 years.

10.1002/cdt3.62 article EN cc-by-nc Chronic Diseases and Translational Medicine 2023-03-07

Abstract Background Noncommunicable diseases (NCDs) are the main reasons of mortality worldwide. One every two person is dying due to NCDs in Afghanistan. International policy actors, mainly World Health Organization (WHO), published several reports and declarations on controlling preventing NCDs. This study aimed provide a situation for governance Afghanistan proper solutions identified challenges. Methods We conducted qualitative research utilizing interpretive phenomenology. A...

10.1002/cdt3.118 article EN cc-by-nc Chronic Diseases and Translational Medicine 2024-02-03

Analysis of dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutations in Plasmodium vivax wild isolates has been considered to be a valuable molecular approach for mapping resistance sulphadoxine-pyrimethamine (SP). The present study investigates the frequency SNPs-haplotypes dhfr dhps genes P. clinical circulating two malaria endemic areas Afghanistan. (n = 171) were collected different regions north-west (Herat) east (Nangarhar) Afghanistan 2008. All analysed...

10.1186/1475-2875-9-75 article EN cc-by Malaria Journal 2010-03-14

Human papillomavirus (HPV) vaccination has not been introduced in many countries South-Central Asia, including Afghanistan, despite the sub-region having highest incidence rate of cervical cancer Asia. This study estimates potential health impact and cost-effectiveness HPV Afghanistan to inform national decision-making. An Excel-based static cohort model was used estimate lifetime costs outcomes vaccinating a single 9-year-old girls year 2018 with bivalent vaccine, compared no vaccination....

10.1016/j.vaccine.2019.12.013 article EN cc-by Vaccine 2019-12-20

In January 2018, Afghanistan introduced the monovalent oral rotavirus vaccine (Rotarix) nationwide, administered as a 2-dose series at six and ten weeks of age. We describe characteristics intussusception cases assess potential risk associated with Rotarix vaccination in Afghan infants. Multi-center prospective active hospital-based surveillance for was conducted from May 2018 to March 2022 four sentinel sites Afghanistan. applied Brighton Level 1 criteria verified status by reviewing cards....

10.1016/j.vaccine.2024.02.057 article EN cc-by Vaccine 2024-02-26

Afghanistan introduced monovalent rotavirus vaccine (Rotarix) into its national immunisation schedule in January, 2018. While post-licensure studies have shown substantial declines gastroenteritis cases and deaths globally, there is little evidence of effectiveness impact from low-income countries Asia. We aimed to evaluate the Rotarix on hospitalisations (ie, hospital admissions) among children younger than 5 years Afghanistan.

10.1016/s2214-109x(24)00237-7 article EN cc-by The Lancet Global Health 2024-08-14

Accurate parasitological diagnosis of malaria is essential for targeting treatment where more than one species coexist. In this study, three rapid diagnostic tests (RDTs) (AccessBio CareStart (CSPfPan), PfPv (CSPfPv) and Standard Diagnostics Bioline (SDBPfPv)) were evaluated their ability to detect natural Plasmodium vivax infections in a basic clinic setting. The potential locally made evaporative cooling boxes (ECB) protect the from heat damage high summer temperatures was also...

10.1186/1475-2875-10-169 article EN cc-by Malaria Journal 2011-06-22

Background A serious worldwide effort to strengthen research based knowledge translation (KT) has begun in recent years and some countries, particularly developed ones, are trying incorporate KT their health systems. Keeping mind the economic depression need perform more efficient research, we aimed assess compare status of selected institutes Eastern Mediterranean Regions' identify strengths weaknesses field. Methods After finding focal points that would steer focus group discussions (FGDs)...

10.1371/journal.pone.0103732 article EN cc-by PLoS ONE 2014-09-08

Despite large-scale investment in health service delivery outsourcing, few studies have examined human resources for (HRH) Afghanistan.To review the HRH situation of outsourced healthcare services Afghanistan and evaluate nongovernment organization (NGO) investments workforce.Two questionnaires were used data collection. One gathered information about characteristics 2020 other collected budgetary 2017-2020 to analyse budget allocation expenditure by NGOs on workforce.A total 25 262 (65%...

10.26719/emhj.23.031 article FR Eastern Mediterranean Health Journal 2023-02-15

Despite progress made in child survival the past 20 years, 5.9 million children under five years died 2015, with 9% of these deaths due to diarrhea. Rotavirus is responsible for more than a third diarrhea deaths. In 2013, rotavirus was estimated cause 215,000 among including 89,000 Asia. As April 2017, 92 countries worldwide have introduced vaccination their national immunization program. Afghanistan has applied Gavi support introduce nationally. This study estimates potential impact and...

10.1016/j.vaccine.2017.10.058 article EN cc-by Vaccine 2017-10-26
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