A5032751090- HIV/AIDS Research and Interventions
- Global Maternal and Child Health
- Adolescent Sexual and Reproductive Health
- HIV/AIDS Impact and Responses
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- Maternal Mental Health During Pregnancy and Postpartum
- HIV-related health complications and treatments
- Environmental Justice and Health Disparities
- Adolescent and Pediatric Healthcare
- Health Policy Implementation Science
- Climate Change and Health Impacts
- Air Quality and Health Impacts
- Healthcare Policy and Management
- Poverty, Education, and Child Welfare
- Global Health Care Issues
- Prenatal Screening and Diagnostics
- HIV, Drug Use, Sexual Risk
University of Malawi
2018-2024
Kamuzu Central Hospital
2018-2022
In Malawi's PMTCT Option B+ program, HIV-infected pregnant women who are already receiving ART continued on their current therapy regimen without testing for treatment failure at the first antenatal care (ANC) visit. HIV RNA screening ANC may identify with and ensure that viral suppression is maintained throughout pregnancy.We conducted a cross-sectional study of had been least 6 months visit under program Bwaila Hospital in Lilongwe, Malawi from June 2015 to December 2017. Poisson...
The association between low-frequency HIV-1 drug resistance mutations (DRMs) and treatment failure (TF) is controversial. We explore this using NGS methods that accurately sample DRMs.
Introduction Long-term care engagement of women on antiretroviral therapy (ART) is essential to effective HIV public health measures. We sought explore factors associated with a history treatment interruption among pregnant living presenting an antenatal clinic in Lilongwe, Malawi. Methods performed cross-sectional study who had ART for care. Women were categorized as either retained or reinitiating after loss-to-follow up (LTFU). To understand interruption, we surveyed socio-demographic and...
Objective: To estimate the association of probable antenatal depression with postpartum HIV care engagement among pregnant women in Malawi. Design: We conducted a prospective cohort study 299 who were initiating antiretroviral therapy (ART) through Option B+ at government clinic Methods: Probable was assessed on day ART initiation validated Chichewa version Edinburgh Postnatal Depression Scale (EPDS). estimated crude and adjusted risk differences (RD, aRD) visit attendance prevalence (PD,...
Malawi's Option B+ universal antiretroviral therapy (ART) program for pregnant and breastfeeding women does not include routine laboratory monitoring. We report safety outcomes of who initiated ART through B+.We analysed 12-month data from an observational cohort study on among newly initiating tenofovir/lamivudine/efavirenz (TDF/3TC/EFV) at a government antenatal clinic in Lilongwe, Malawi. Proportions engaged care, incidence DAIDS grade ≥ 2 toxicity, 3 adverse events (AEs), viral...
Antiretroviral therapy (ART) is very effective in preventing vertical transmission of HIV but some women on ART experience different virologic, immunologic, and safety profiles. While most pregnant are closely monitored for short-term effects during pregnancy, few receive similar attention beyond pregnancy. We aimed to assess retention care clinical laboratory-confirmed outcomes over 3 years after starting under Malawi's Option B + program.
Option B + provides lifelong ART to pregnant and breastfeeding women with HIV reduce mother-to-child transmission of (eMTCT) improve maternal health. The effectiveness relies on continuous engagement, but suboptimal monitoring care hinders our measurements engagement. Process mapping quality improvement (PROMAQI) is a strategy for healthcare workers (HCWs) optimize complex processes such as care. We assessed the acceptability feasibility PROMAQI among HCWs identified barriers facilitators...
Background Option B+ aims to prevent mother-to-child transmission of HIV by providing lifelong antiretroviral therapy (ART) pregnant and breastfeeding women living with (PBWHIV). Identifying reengaging PBWHIV who disengage or fail initiate ART is essential for the success B+. However, process often suboptimal, leading challenges such as misclassification patients lost follow-up. Healthcare workers (HCWs) are pivotal monitoring engagement, but little known about their practices. This study...