Denise M. Roche

ORCID: 0000-0003-0045-0645
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About
Contact & Profiles
Research Areas
  • Cardiovascular and exercise physiology
  • Sports Performance and Training
  • Cardiovascular Effects of Exercise
  • Heart Rate Variability and Autonomic Control
  • Cardiovascular Function and Risk Factors
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Physical Activity and Health
  • Diabetes Management and Research
  • Health and Lifestyle Studies
  • Thermoregulation and physiological responses
  • Cardiovascular Health and Disease Prevention
  • Sports injuries and prevention
  • Sports and Physical Education Research
  • Infrared Thermography in Medicine
  • Respiratory Support and Mechanisms
  • Muscle activation and electromyography studies
  • Healthcare Facilities Design and Sustainability
  • Diet and metabolism studies
  • HIV/AIDS Impact and Responses
  • Nutrition and Health in Aging
  • Obesity, Physical Activity, Diet
  • Viral Infections and Vectors
  • Sports Analytics and Performance
  • Vascular Malformations and Hemangiomas
  • Tracheal and airway disorders

Liverpool Hope University
2009-2021

Loughborough University
2011

University of Staffordshire
2011

Baystate Medical Center
2009

Université Paris Cité
1975

Sorbonne Université
1975

Purpose: The extent that enhanced ventricular function contributes to superior aerobic fitness of trained athletes is unclear. This study compared cardiovascular responses progressive cycle exercise in 12 adolescent soccer players and 10 untrained boys with assessment inotropic relaxation properties by Doppler ultrasound techniques. Methods: Resting cardiac dimensions were measured M-mode echocardiography. Stroke volume was estimated the technique, systolic peak aortic flow velocity ejection...

10.1249/mss.0b013e3181a06cb5 article EN Medicine & Science in Sports & Exercise 2009-08-13

Exercise training results in a speeding of pulmonary oxygen uptake (VO2) kinetics at the onset exercise adults; however, only limited research has been conducted with children and adolescents.The aim present study was to examine VO2 muscle deoxygenation trained untrained male adolescents.Sixteen (15 +/- 0.8 yr, VO2peak = 54.7 6.2 mL x kg-1 min-1, self-assessed Tanner stage range 2-4) nine 0.6 43.1 5.2 adolescents performed two 6-min transitions from 3-min baseline 10 W workload equivalent...

10.1249/mss.0b013e3181af20d0 article EN Medicine & Science in Sports & Exercise 2009-12-12

In Ireland bovine babesiosis is caused by the tick-borne blood parasite, Babesia divergens. A survey of veterinary practitioners and farmers in 1980’s revealed an annual incidence 1.7% associated with considerable economic losses. However, two subsequent surveys 1990’s indicated a decline clinical babesiosis. Recent evidence from continental Europe suggests that, probably due to climate change, distribution tick vector B. divergens, Ixodes ricinus extending more northerly regions higher...

10.1186/2046-0481-67-19 article EN cc-by Irish Veterinary Journal 2014-09-05

New Findings What is the central question of this study? Critical power (CP) represents highest work rate for which a metabolic steady state attainable. The physiological determinants CP are unclear, but research suggests that might be related to time constant phase II oxygen uptake kinetics ( ). main finding and its importance? We provide first evidence mechanistically CP. A reduction in supine position was observed alongside concomitant increase This effect may contingent on measures...

10.1113/ep086304 article EN Experimental Physiology 2017-06-19

Physical activity and psychological well-being contribute to positive lifestyle in youngsters who have Type 1 diabetes. The aims of this study were objectively assess the physical levels children with diabetes, investigate associations between levels, HbA(1c). Thirty-six children, mean age 12.8 years, participated investigation. was assessed using heart rate monitoring over four days. Children further completed Diabetes Quality Life for Youths Questionnaire, Self-Perception Profile...

10.1080/13548500600975446 article EN Psychology Health & Medicine 2007-05-01

ABSTRACT Introduction/Purpose Critical power (CP) is a fundamental parameter defining high-intensity exercise tolerance; however, its physiological determinants are incompletely understood. The present study determined the impact of hyperoxia on CP, time constant phase II pulmonary oxygen uptake kinetics (τ V˙O2 ), and muscle oxygenation (assessed by near-infrared spectroscopy) in nine healthy men performing upright cycle ergometry. Methods was normoxia (fraction inspired O 2 = 0.5) via four...

10.1249/mss.0000000000002234 article EN Medicine & Science in Sports & Exercise 2019-12-06

What is the central question of this study? Critical power a fundamental parameter defining high-intensity exercise tolerance and related to phase II time constant pulmonary oxygen uptake kinetics ( τV̇O2 ). To test whether relationship causal, we assessed impact hyperoxia on critical during supine cycle exercise. main finding its importance? The results demonstrate that increased muscle oxygenation, reduced (i.e. sped up kinetics) and, subsequently, when compared with normoxia. These...

10.1113/ep087599 article EN Experimental Physiology 2019-05-06

No studies to date have evaluated the relationship between exercise and microvascular function in youth with type 1 diabetes mellitus (T1DM). Twenty-nine complication free children adolescents T1DM were assessed for skin reactivity, aerobic fitness (VO2 peak ) physical activity. VO2 but not activity was significantly independently associated maximal hyperemia of microcirculation ( p < .01). significant associations found venoarte-riolar reflex (VAR) vasoconstriction or Aerobic may be an...

10.1123/pes.20.4.426 article EN Pediatric Exercise Science 2008-11-01

Background: The current study objectively assessed physical activity (PA) levels and patterns in children adolescents with type 1 diabetes compared the metabolic physiologic health profiles of those achieving not recommendation 60 minutes a day (minutes·D −1 ) at least moderate intensity PA. Method: 37 (20 boys, 17 girls) aged 12.7 ± 2.1 years (mean SD), disease duration 5.9 3.0 participated. PA was using heart rate monitoring. Peak VO 2 , BMI, sum 5 skinfolds, HbA 1c daily insulin dosage...

10.1123/jpah.7.1.68 article EN Journal of Physical Activity and Health 2010-01-01

Critical power is a fundamental parameter defining high-intensity exercise tolerance, and related to the phase II time constant of pulmonary oxygen uptake kinetics (). Whether this relationship causative presently unclear. This study determined impact raised baseline work rate, which increases , on critical during upright cycle exercise. was via four constant-power tests exhaustion in two conditions: (1) with initiated from an unloaded cycling (U→S), (2) rate 90% gas exchange threshold...

10.14814/phy2.13802 article EN cc-by Physiological Reports 2018-07-01

We have previously demonstrated that the phase II time constant of pulmonary oxygen uptake kinetics () is an independent determinant critical power (CP) when O2 availability not limiting, is, during upright cycle exercise in young, healthy individuals. Whether this causative relationship remains impaired unknown. During supine exercise, which causes limitation transition, we therefore determined impact a raised baseline work rate on and CP. CP, , muscle oxygenation status (the latter via...

10.14814/phy2.13916 article EN cc-by Physiological Reports 2018-11-01

Patients with type 1 diabetes demonstrated slower oxygen uptake (V̇o 2 ) kinetics compared healthy control subjects. Furthermore, a prior bout of high-intensity exercise speeded V̇o and increased critical power in people diabetes. Prior muscle deoxygenation kinetics, indicating that are limited primarily by extraction and/or intracellular factors. These findings highlight the potential for interventions decrease metabolic inertia enhancing tolerance this condition.

10.1152/japplphysiol.00892.2019 article EN Journal of Applied Physiology 2020-03-26

The prevalence of musculoskeletal (MSK) conditions is increasing, and although current guidelines for physical activity attempt to combat this, many fail achieve the recommended targets. present study sought investigate whether regular tennis participation more effective at enhancing MSK function than meeting international guidelines.Tennis players will display significantly enhanced when compared with age-matched healthy active nonplayers.Cross-sectional study.Level 3.Ninety participants...

10.1177/1941738119880862 article EN Sports Health A Multidisciplinary Approach 2019-11-11

This study was designed to examine time-of-day effects on markers of cardiac functional capacity during a standard progressive cycle exercise test. Fourteen healthy, untrained young males (mean ± SD: 17.9 0.7 yrs age) performed identical maximal tests in the morning (08:00–11:00 h) and late afternoon (16:00–19:00 random order. Cardiac variables were measured at rest, submaximal exercise, by echocardiographic techniques. No differences testing values rest or observed for oxygen uptake, heart...

10.3109/07420528.2011.597909 article EN Chronobiology International 2011-07-26

Orthostatic‐induced alterations in Doppler echocardiographic measures of ventricular function have not been well‐defined. Identifying such changes may provide useful insights regarding the responses these to variations loading conditions. Standard assessment mitral inflow velocity and tissue imaging (TDI) left longitudinal myocardial velocities was performed on 14 young males (mean age 17.9 ± 0.7 years) supine position then 5 minutes after assuming a sitting with legs dependent. Upon...

10.1111/j.1540-8175.2011.01634.x article EN Echocardiography 2012-02-13

Little evidence exists with regard to changes in cardiac strain that occur during submaximal exercise young males. The aims of the study were evaluate longitudinal (L), radial (R), and endocardial circumferential ( EC ) upright cycle ergometry examine test–retest reproducibility these measurements. Fourteen recreationally active, adolescent (age: 17.9 ± 0.7 years) males volunteered for study. All subjects underwent an incremental (40 W) ergometer test. L, R, values obtained using speckle...

10.1111/echo.12708 article EN Echocardiography 2014-08-13

Abstract Objectives: Ventricular systolic functional response to exercise has been reported be superior in adult men compared women. This study explored myocardial responses maximal upright progressive late pubertal males and females. Methods: Doppler echocardiographic techniques were utilized estimate function a bout of cycle exercise. Results: Systolic capacity, as indicated by ejection rate (12.5 ± 2.8 13.1 1.0 [×10 −2 ] ml s −1 cm for boys girls, respectively) peak aortic velocity (208...

10.1002/ajhb.21065 article EN American Journal of Human Biology 2010-05-27
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