A5086561752- Seaweed-derived Bioactive Compounds
- Polysaccharides and Plant Cell Walls
- Marine Sponges and Natural Products
- Natural product bioactivities and synthesis
- Phytochemical and Pharmacological Studies
- Phytochemistry and Biological Activities
- Moringa oleifera research and applications
- Proteoglycans and glycosaminoglycans research
- Ocular Surface and Contact Lens
- Natural Antidiabetic Agents Studies
- Herbal Medicine and Trade Cooperation
- Phytochemistry and Bioactivity Studies
- Polysaccharides Composition and Applications
- Algal biology and biofuel production
- Microbial Metabolites in Food Biotechnology
- Echinoderm biology and ecology
- Botanical Research and Applications
- Phytochemistry and Bioactive Compounds
- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
University of Monastir
2017-2019
Brown seaweeds produce useful bioactive substances with high cosmetic and pharmacological values due to the presence of antioxidant derivatives, mainly phlorotannins (PHT), which are particular interest. A central composite rotatable design (CCRD) three variables (extraction time, dry material-to-solvent ratio ethanol concentration) two responses was performed optimize microwave-assisted extraction (MAE) from Cystoseira sedoides using response surface methodology (RSM). Results showed that...
Microwave-assisted extraction was employed for the isolation of polysaccharides from Posidonia oceanica (PPO). The extracting parameters were optimized adopting response surface methodology. highest polysaccharide yield (2.55 ± 0.09%), which is in concordance with predicted value (2.76%), obtained under following conditions: time 60 s, liquid-solid ratio 50:1 (mL/g) and power 800 W. This polysaccharide, molecular weight 524 KDa, characterized by gas chromatography-mass spectrometry showed...
Background and Aim: Natural products continue to be a primary resource in biomedicine biotechnology. The marine environment is highly reserve for novel pharmaceutical medical compounds. aim of this work was identify bioactive components from the brown seaweed Padina pavonica with specific pharmacological potential. Methods: In present study, we investigated efficacy polyphenol fraction vivo anti-inflammatory activity using carrageen an-induced paw edema model rats there vitro antioxidant two...
Objective: To investigate the anticancer activity of two diterpenes [palmonine F (C1) and palmonine D (C2)] three steroids [cholesta-5,22-dien-3β-ol (C3), stigmasterol (C4) 5α-cholest-5-en-3β-ol (C5)], isolated from Mediterranean gorgonian Eunicella singularis, against MCF-7 breast cancer cell line.Methods: This study was performed on standard monolayer two-dimensional (2D) model to evaluate apoptosis by means AnnexinV-FITC/PI flow cytometry three-dimensional (3D) spheroid using Celigo...