Özçaka Ö, Başoğlu ÖK, Buduneli N, Taşbakan MS, Bacakoğlu F, Kinane DF. Chlorhexidine decreases the risk of ventilator‐associated pneumonia in intensive care unit patients: a randomized clinical trial. J Periodont Res 2012; 47: 584–592. © 2012 John Wiley & Sons A/S Background and Objective: The aim was to evaluate whether oral swabbing with 0.2% chlorhexidine gluconate (CHX) (VAP) (ICU) patients. Material Methods: Sixty‐one dentate patients scheduled for invasive mechanical ventilation at...

Özçaka Ö, Nalbantsoy A, Buduneli N. Interleukin-17 and interleukin-18 levels in saliva plasma of patients with chronic periodontitis. J Periodont Res 2011; 46: 592–598. © 2011 John Wiley & Sons A/S Background Objective: This study was planned to investigate whether periodontitis exhibit different salivary and/or concentrations interleukin (IL)-17 IL-18 compared clinically healthy subjects. Material Methods: Whole blood samples, together full-mouth clinical periodontal recordings, were...

Polycystic ovary syndrome (PCOS) is a hormonal disorder of women that not only the leading cause infertility but also shows reciprocal link with oral health. This study aimed to investigate hypothesis levels putative periodontal pathogens in saliva and their antibody response serum are elevated PCOS, compared systemic A total 125 were included four groups; 45 PCOS healthy periodontium, 35 gingivitis, 25 systemically periodontally women, 20 gingivitis. Salivary seven analyzed by quantitative...

To investigate possible relationship between smoking and serum concentrations of matrix metalloproteinase-8,-9 (MMP-8, MMP-9), tissue inhibitor metalloproteinases-1 (TIMP-1), neutrophil elastase (NE), myeloperoxidase (MPO) in chronic periodontitis (CP) patients relative to periodontally healthy subjects.Serum samples were obtained from 111 subjects before initiation any periodontal intervention. Fifty-five CP (39 non-smokers, 16 smokers) 56 17 recruited. Serum MMP-8 determined by IFMA MPO,...

Polycystic ovarian syndrome (PCOS) is a hormonal disorder of females reproductive age that impacts their oral and systemic health. The aim this study to evaluate interleukin-17A (IL-17A), IL-17F, IL-17A/F, IL-17E (IL-25) levels in gingival crevicular fluid (GCF), saliva, serum non-obese with PCOS either clinically healthy periodontium or gingivitis.Thirty-one PCOS, 30 gingivitis, 12 systemically periodontally participated the study. Clinical periodontal measurements, body mass index,...

Abstract Aim Gestational diabetes mellitus ( GDM ), gingivitis, infection with specific periodontal pathogens and systemic inflammation each increase the risk for poor pregnancy outcome. We set out to monitor interactions of gingivitis respect oral inflammatory burden. Materials Methods Four case–control groups n = 117) were recruited, (1) No , 27); (2) Gingivitis 31); (3) 21); (4) Gingivitis, 38). Oral three key was determined by PCR . Systemic quantification CRP EIA Results during...

Background: Fluctuations in sex steroid hormones, which are also noticeable through the menstrual cycle of women, may impact periodontal health. The aim this study is to evaluate effect hormonal changes occurring on gingival inflammation and crevicular fluid (GCF) levels interleukin 6 (IL‐6), prostaglandin E 2 (PGE ), tissue plasminogen activator (t‐PA), inhibitor‐2 (PAI‐2). Methods: Twenty‐five gingivitis patients 25 periodontally healthy subjects having regular cycles were seen at...

Background: The aim of this study is to evaluate the gingival crevicular fluid (GCF), saliva, and serum concentrations tumor necrosis factor‐α (TNF‐α), TNF‐α receptor‐1 (TNF‐αR1), TNF‐αR2, interleukin‐6 (IL‐6) in non‐obese females with polycystic ovary syndrome (PCOS) either clinically healthy periodontium or gingivitis. Methods: Thirty‐one PCOS periodontium, 30 gingivitis, 12 systemically periodontally were included study. GCF, samples collected, clinical periodontal measurements, body mass...

Background: Pentraxin‐3 (PTX3) is a multifactorial protein involved in immunity and inflammation, which rapidly produced released by several cell types response to inflammatory signals. The aim of the present study evaluate saliva, serum levels PTX3, interleukin (IL)‐1β patients with generalized chronic periodontitis (CP) or aggressive (AgP), periodontally healthy individuals. Methods: A total 94 participants (25 AgP, 25 CP, 44 individuals matched AgP CP groups) were recruited. Saliva...

Background: This study investigates whether gingival crevicular fluid (GCF), saliva, and plasma levels of interleukin‐33 (IL‐33) can differentiate individuals with chronic periodontitis from healthy periodontium. Methods: GCF, whole samples together full‐mouth clinical periodontal recordings were obtained 32 otherwise healthy, non‐smoker 25 systemically periodontally individuals. IL‐33 in the biofluid determined by enzyme‐linked immunosorbent assay. Data tested statistically Mann‐Whitney U...

This study aimed to investigate the levels of matrix metalloproteinase-8 (MMP-8) and tissue inhibitors MMP-1 (TIMP-1) in saliva serum samples women with polycystic ovary syndrome (PCOS; n = 80) matched systemically healthy controls (n 45), varying degrees gingival inflammation. Salivary MMP-8 MMP-8/TIMP-1 ratio were significantly elevated PCOS, who also exhibited more gingivitis than women. No major changes observed salivary TIMP-1 regard PCOS. Serum higher irrespective presence gingivitis,...

This cross-sectional study was planned to investigate whether patients with chronic periodontitis exhibit different salivary or plasma concentrations of Toll-like receptor (TLR) 2 and TLR4 compared subjects who are clinically healthy.Whole saliva samples were obtained full-mouth clinical periodontal measurements recorded from 22 otherwise healthy 21 systemically periodontally control subjects. Salivary TLR2 levels determined by enzyme-linked immunoassays. Data tested statistically using...

Background: Gestational diabetes mellitus (GDM) is defined as varying glucose intolerance, with first onset or recognition in pregnancy. This study evaluates clinical and biochemical parameters a possible association between GDM gingivitis. Methods: A total of 167 pregnant females was included the study. There were 101 66 without GDM. Subgroups created according to presence absence gingival inflammation. Plaque index, bleeding on probing, probing depth recorded at four sites per tooth....

Abstract Background: The aim of this study was to evaluate plasma levels soluble receptor activator nuclear factor‐kappa B ligand (sRANKL) and osteoprotegerin (OPG) in smoker versus non‐smoker chronic periodontitis patients. Methods: Plasma samples were obtained from 13 31 systemically healthy patients, as well 29 periodontally subjects. Before commencing any periodontal intervention, venous blood whole‐mouth clinical measurements recorded. sRANKL OPG concentrations determined by...

Background: The objective of this cross‐sectional study is to investigate levels salivary and serum matrix metalloproteinase (MMP)‐9, myeloperoxidase (MPO), neutrophil elastase (NE), MMP‐9/tissue inhibitor MMP‐1 (TIMP)‐1 ratio in patients with polycystic ovary syndrome (PCOS) systemically healthy controls the presence or absence gingivitis. Methods: Serum these biomarkers were evaluated following: 1) periodontally women PCOS (n = 45); 2) gingivitis 35); 3) 25); 4) 20). Enzyme‐linked...

The aim of this cross-sectional study is to compare the local and systemic levels soluble receptor activator nuclear factor-κB ligand (sRANKL), osteoprotegerin (OPG), a proliferation-inducing (APRIL), B-cell activating factor (BAFF), interleukin (IL)-6, IL-8 in biofluids patients with thalassemia major (TM) or without gingivitis.Seventy-seven are included (TM, n = 29; systemically healthy, 48). Gingival crevicular fluid (GCF), saliva, serum IL-6, IL-8, sRANKL, OPG, BAFF, APRIL were...

Oral Diseases (2011) 17 , 200–205 Objectives: This study was planned to investigate whether smoker chronic periodontitis patients exhibit different salivary concentrations of C‐telopeptide pyridinoline cross‐links type I collagen (ICTP) and osteocalcin (OC) compared the non‐smoker counterparts. Methods: Whole saliva samples, full‐mouth clinical periodontal recordings were obtained from 33 otherwise healthy 36 systemically, periodontally control subjects. Chronic subjects divided into groups...

Background: This study evaluates levels of matrix metalloproteinase (MMP)‐8, MMP‐9, and tissue inhibitor MP‐1 (TIMP‐1) in biofluids women with gestational diabetes mellitus (GDM) systemically healthy counterparts different statuses periodontal health. Methods: Seventy‐one GDM gingivitis (Gg), 30 periodontium (Gh), 28 periodontally (Hh), 37 (Hg) were evaluated. MMP‐8, TIMP‐1 determined gingival crevicular fluid (GCF), saliva, serum by immunofluorometric enzyme‐linked immunosorbent assays....

The aim of the present study is to compare clinical periodontal findings as well gingival crevicular fluid (GCF) and plasma levels tumor necrosis factor-alpha (TNF-α), interleukin-1beta (IL-1β), interferon gamma (IFN-γ) caspase-1 in primary Sjögren syndrome (pSS) rheumatoid arthritis (RA) subjects.In case control GCF samples were collected, full-mouth recordings comprising plaque index (PI), bleeding on probing (BOP) depth (PD) performed 44 subjects with pSS, 39 RA 30 systemically healthy...

Abstract Objectives: The aim of this pilot cross‐over study was to compare preliminarily the pain perception female patients undergoing periodontal debridement during menstrual or pre‐menstrual phases (peri‐menstrual period) with that observed mid‐menstrual phase (post‐menstrual period). Materials and Methods: Twenty women moderate‐to‐advanced chronic periodontitis regular cycles were asked complete Corah's Dental Anxiety Scale (DAS) first visit. Patients randomly assigned receive their...