Xin Zhang

ORCID: 0000-0003-0047-3134
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About
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Research Areas
  • Blood Pressure and Hypertension Studies
  • Atmospheric chemistry and aerosols
  • Heavy metals in environment
  • Arsenic contamination and mitigation
  • Advanced Chemical Sensor Technologies
  • Air Quality and Health Impacts
  • Soil Carbon and Nitrogen Dynamics
  • Acupuncture Treatment Research Studies
  • Cardiovascular Health and Disease Prevention
  • Neurological disorders and treatments
  • Cancer Immunotherapy and Biomarkers
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Heart Failure Treatment and Management
  • Cardiovascular Function and Risk Factors
  • Viral Infections and Immunology Research
  • Inhalation and Respiratory Drug Delivery
  • Catalytic C–H Functionalization Methods
  • Cardiac Valve Diseases and Treatments
  • Facial Nerve Paralysis Treatment and Research
  • Biofuel production and bioconversion
  • Methane Hydrates and Related Phenomena
  • Bladder and Urothelial Cancer Treatments
  • Cardiovascular Health and Risk Factors
  • Electrochemical Analysis and Applications
  • Botulinum Toxin and Related Neurological Disorders

Jilin Agricultural University
2024-2025

Tianjin University of Technology and Education
2025

Affiliated Hospital of Shandong University of Traditional Chinese Medicine
2025

Shandong University of Traditional Chinese Medicine
2020-2025

Sichuan University
2014-2025

West China Hospital of Sichuan University
2014-2025

Shanghai Jiao Tong University
2013-2025

Xinjiang Academy of Agricultural and Reclamation Science
2020-2025

Northwest A&F University
2017-2025

Shanxi Medical University
2024-2025

Aberrant protein misfolding may contribute to the pathogenesis of amyotrophic lateral sclerosis (ALS) but detailed mechanisms are largely unknown. Our previous study has shown that autophagy is altered in mouse model ALS. In present study, we systematically investigated correlation autophagic alteration with motor neurons (MNs) degeneration ALS mice. We have demonstrated marker LC3-II markedly and specifically increased spinal cord MNs Electron microscopy immunochemistry studies vacuoles...

10.4161/auto.7.4.14541 article EN Autophagy 2011-03-07

The most widely used catalysts and processes for H2S-selective catalytic oxidation are overviewed in this review. Two kinds of have been investigated intensively: carbon-based (active carbon catalyst, nanotube nanofiber catalyst), metal oxide-based (metal oxide oxide-supported clay-supported catalyst). Among them, utilized mainly discontinuous at relatively low temperatures, whereas the practice. However, reaction temperature is high. Fortunately, a MgAlVO catalyst derived from LDH materials...

10.1021/cs501476p article EN ACS Catalysis 2014-12-26
Markus P. Schlaich M Bellet Michael A. Weber Parisa Danaietash George L. Bakris and 95 more John M. Flack Roland F. Dreier Mouna Sassi-Sayadi Lloyd Haskell Krzysztof Narkiewicz Ji‐Guang Wang Christopher M. Reid Markus P. Schlaich Ivor Katz Andrew E. Ajani Sinjini Biswas Murray Esler Grahame J. Elder Simon D. Roger David Colquhoun John G. Mooney Tine De Backer Alexandre Persu Martin Chaumont Jean-Marie Krzesinski Thomas Vanassche Ginette Girard Lew Pliamm Ernesto L. Schiffrin Fatima Merali George K. Dresser Michel Vallée Shivinder Jolly S. P. Chow Ji‐Guang Wang Jianjun Mu Jing Yu Hong Yuan Yingqing Feng Xin Zhang Jianhong Xie Ling Lin Miroslav Souček J Widimský Renata Cífková J. Václavík Martin Ullrych Martin Lukáč Ivan Rychlík Thomas Guldager Lauridsen Ilkka Kantola Jyrki Taurio Olavi Ukkola Olivier Ormezzano Philippe Gosse Michel Azizi Pierre‐Yves Courand Pascal Delsart Jean Michel Tartiere Felix Mahfoud Roland E. Schmieder Johannes Stegbauer Philipp Lurz Michael Koziolek Christian Ott Nicole Toursarkissian Konstantinos Tsioufis K. Kyfnidis Athanasios Manolis Sotirios Patsilinakos Pantelis Zebekakis Apostolos Karavidas Pall Denes Katalin Bezzegh Marianna Zsom László Kovács Yehonatan Sharabi Mazen Elias Ivetta Sukholutsky Chaim Yosefy Irina Kenis Shaul Atar Massimo Volpe Muiesan Maria Lorenza Stefano Taddei Guıdo Grassı Franco Veglio Jung‐Woo Son Jang‐Young Kim Joong-Il Park Chang Hoon Lee Hae‐Young Lee Rasa Raugalienė Jolanta Elena Marcinkeviciene Roma Kavaliauskiene Jaap Deinum Abraham A. Kroon Bert‐Jan H. van den Born Andrzej Januszewicz Andrzej Tykarski

10.1016/s0140-6736(22)02034-7 article EN The Lancet 2022-11-07

Abstract Background Time-restricted feeding is an emerging dietary intervention that becoming increasingly popular. There are, however, no randomised clinical trials of time-restricted in overweight patients with type 2 diabetes. Here, we explored the effects on glycaemic regulation and weight changes diabetes over 12 weeks. Methods Overweight adults (n = 120) were 1:1 to two diet groups: 60) or control 60). Sixty participated a 10-h restricted treatment program (ad libitum from 8:00 18:00...

10.1186/s12986-021-00613-9 article EN cc-by Nutrition & Metabolism 2021-10-07

Copper is one of the most abundant heavy metals present in swine manure. In this study, a laboratory-scale aerobic composting system was amended with Cu at three levels (0, 200, and 2000 mg kg−1, i.e., control, Cu200, Cu2000 treatments, respectively) to determine its effect on fate copper resistance genes (CRGs: pcoA, cusA, copA, tcrB), antibiotic (ARGs: erm(A) erm(B)) intl1. The results showed that absolute abundances tcrB, erm(A), erm(B) intl1 were reduced, whereas those copA cusA...

10.3389/fmicb.2017.00344 article EN cc-by Frontiers in Microbiology 2017-03-03

Abstract The efficient selective oxidation and functionalization of CH bonds with molecular oxygen a copper catalyst to prepare the corresponding ketones was achieved ethyl chloroacetate as promoter. In this transformation, various substituted N‐heterocyclic compounds were well tolerated. Preliminary mechanistic investigations indicated that organic radical species involved in overall process. work synergistically activate methylene group, which results easy generation free intermediates,...

10.1002/ange.201409580 article EN Angewandte Chemie 2014-12-05

Abstract. The impacts of black carbon (BC) aerosols on air quality, boundary layer dynamics and climate depend not only the BC mass concentration but also light absorption capability BC. It is well known that depends amount coating materials (namely other species condense coagulate BC). However, difference ambient BC-containing particles under different pollution conditions (e.g., clean polluted conditions) remains unclear due to complex aging process in atmosphere. In this work, we...

10.5194/acp-18-9879-2018 article EN cc-by Atmospheric chemistry and physics 2018-07-13

In this study, potent coumarin derivatives containing oxime ester 1 ∼ 28 as α-glucosidase inhibitors were developed through a stepwise structure optimization, and the activity relationship was uncovered. Among them, compound 20 exhibited outstanding inhibitory with IC50 of 2.54 ± 0.04 μM compared to 640.57 1.13 Acarbose. Kinetic study ascertained that reversible uncompetitive inhibitor. 3D fluorescence results showed interaction caused changes microenvironments polypeptide backbone...

10.1016/j.arabjc.2022.104072 article EN cc-by-nc-nd Arabian Journal of Chemistry 2022-06-26

Under the catalysis of PdBr2 and a chiral phosphoramidite ligand, upper-rim mono (2-bromoaroyl)-substituted calix[4]arene derivatives underwent facile enantioselective desymmetrization reaction to afford 9H-fluorene-embedded inherently calixarenes in good yields with excellent enantioselectivities. The transannular dehydrogenative arene-arene coupling proceeded most probably through an oxidative addition Caryl-Br bond ligated palladium catalyst followed by sequence 1,5-palladium migration...

10.1039/d2sc06234h article EN cc-by Chemical Science 2022-12-06
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