A5055215787- Seaweed-derived Bioactive Compounds
- Tissue Engineering and Regenerative Medicine
- Echinoderm biology and ecology
- Marine Invertebrate Physiology and Ecology
- Organ Transplantation Techniques and Outcomes
- Urological Disorders and Treatments
- Extracellular vesicles in disease
- Aquatic life and conservation
- Corneal Surgery and Treatments
- Microplastics and Plastic Pollution
- Xenotransplantation and immune response
- Biotechnology and Related Fields
- International Maritime Law Issues
- Organ Donation and Transplantation
- Science, Research, and Medicine
- Molecular Communication and Nanonetworks
- Wound Healing and Treatments
- Graphene and Nanomaterials Applications
Bushehr University of Medical Sciences
2020-2024
Biotechnology Research Center
2020-2024
Marine invertebrates are multicellular organisms consisting of a wide range marine environmental species. Unlike vertebrates, including humans, one the challenges in identifying and tracking invertebrate stem cells is lack specific marker. Labeling with magnetic particles provides non-invasive, vivo method using MRI. This study suggests antibody-conjugated iron nanoparticles (NPs), which detectable MRI for tracking, to detect cell proliferation Oct4 receptor as marker cells. In first phase,...
Regenerative effects of sea anemone-derived exosomes on human foreskin fibroblasts (HFFs) were investigated. Water-based extracts from regenerating Aulactinia stella tissue collected at various time points, and extracted after inducing wounds. Both the extract tested HFF for proliferation in vitro wound healing. In silico analysis explored protein–protein docking between regenerative exosome proteins receptors. The MTT (3-(4,5-dimethylthiazol-2yl)-2,5 diphenyltetrazolium bromide assay...
Sea cucumber extracts and their bioactive compounds have the potential for stem cell proliferation induction beneficial therapeutic properties. In this study, human umbilical cord mesenchymal stromal/stem cells (hUC-MSCs) were exposed to an aqueous extract of Holothuria parva body walls. Proliferative molecules detected using gas chromatography-mass spectrometry (GC-MS) analysis in H. parva. The concentrations 5, 10, 20, 40, 80 µg/mL 10 20 ng/mL epidermal growth factor (EGF) as positive...
Abstract This study evaluated the possible regenerative effects of proliferating sea anemone cells-derived exosomes on human foreskin fibroblasts (HFF). Water-based extracts from Aulactinia stella tissue 48 h after regeneration was collected. The anemone, species were wounded middle column and extracted 0 h, 24 72 96 wound induction. extract separately analyzed HFF using MTT for proliferation in vitro healing cell migration test. Additionally, an in-silico analysis performed to investigate...
Chronic kidney diseases (CKD) and end stage renal disease (ESRD) are growing threats worldwide. Tissue engineering is a new hope to surpass the current limitations such as shortage of donor. To do so, first step would be fabrication an intact decellularized scaffold. In study, automatic decellularization device was developed perfuse decellularize male rats' kidneys using both sodium lauryl ether sulfate (SLES) dodecyl (SDS) compare their efficacy in post-transplantation angiogenesis. After...
Abstract Background : The sea cucumber potentials for stem cell proliferation induction and their mechanisms of bioactive compounds in its extract have been studied. Human umbilical cord mesenchymal stromal/stem cells (hUC-MSCs) were exposed to aqueous Holothuria parva body wall. Methods Using GC-MS analysis on H. , proliferative molecules detected. concentrations 5, 10, 20, 40, 80 µg/mL 10 20 ng/mL human epidermal growth factor (EGF) as positive controls used. MTT proliferation, count,...
Abstract Background : The sea cucumber potentials for stem cell proliferation induction and their mechanisms of bioactive compounds in its extract have been studied. Human umbilical cord mesenchymal stromal/stem cells (hUC-MSCs) were exposed to aqueous Holothuria parva body wall. Methods Using GC-MS analysis on H. , proliferative molecules detected. concentrations 5, 10, 20, 40, 80 µg/mL 10 20 ng/mL human epidermal growth factor (EGF) as positive controls used. MTT proliferation, count,...
Abstract Background : Chronic kidney diseases and end stage renal disease are growing threats worldwide. Tissue engineering is a new hope to surpass the current limitations such as shortage of donor. To do so, first step would be fabrication an intact decellularized scaffold. In study, automatic decellularization device was developed perfuse decellularize male rats' kidneys using both sodium lauryl ether sulfate (SLES) dodecyl (SDS) compare their efficacy in post-transplantation...
Background Marine biological resources and their creatures are one of the major parts marine biomass.Marine important for regular genetic research isolation extraction materials from organisms which have potential commercial development employment in coastal areas.Marine Biobank, addition to setting up a joint venture, will co-ordinate measurments protection biodiversity biotechnological applications at universities by: a) Setting technological tools common practices keep records whole...