A5036891134- Orthopedic Surgery and Rehabilitation
- Tendon Structure and Treatment
- RNA Research and Splicing
- Cancer Cells and Metastasis
- Orthopedic Infections and Treatments
- Sports injuries and prevention
- Orthopaedic implants and arthroplasty
- Spine and Intervertebral Disc Pathology
- Anesthesia and Pain Management
- Cytokine Signaling Pathways and Interactions
- Infective Endocarditis Diagnosis and Management
- Medical Malpractice and Liability Issues
- Elbow and Forearm Trauma Treatment
- Myofascial pain diagnosis and treatment
Ottawa Hospital
2022-2024
University of Ottawa
2022-2024
St. Paul's Hospital
2020
University of British Columbia
2013-2020
Child and Family Research Institute
2013
Triple-negative breast cancers (TNBC) are notoriously difficult to treat because they lack hormone receptors and have limited targeted therapies. Recently, we demonstrated that p90 ribosomal S6 kinase (RSK) is essential for TNBC growth survival indicating it as a target therapeutic development. RSK phosphorylates Y-box binding protein-1 (YB-1), an oncogenic transcription/translation factor, highly expressed in (~70% of cases) associated with poor prognosis, drug resistance tumor initiation....
Peripheral nerve blocks (PNBs) have revolutionized distal extremity surgery reducing pain and improving hospital efficiency. Perineural dexamethasone has been administered with PNBs to prolong their effects, although the safety of not established in literature. This study aimed determine if addition affected postoperative neurological sensory status for foot ankle surgeries recovery injuries. We hypothesized that rate persistent injury would be higher group.This is a retrospective...
This study compared the responsiveness of a generic (Short Form-36 [SF-36]), an upper extremity-specific (Disabilities Arm, Shoulder, and Hand [DASH]) wrist-specific (Patient-Rated Wrist Evaluation [PRWE]) outcome score when evaluating distal radius fractures over time.We observed 235 patients who met inclusion criteria isolated fracture treated surgically or nonsurgically greater than age 50 years for 12 months in this prospective study. Standardized assessments were performed at baseline 6...