The elderly population differs from adults because they have numerous comorbid conditions and pharmacokinetics pharmacodynamics profiles. study aimed to detect inappropriate prescriptions in patients using online tools a tertiary care teaching hospital Central India. This was carried out inpatients who were prescribed more than five drugs determine the medications. For this, such as MedStopper, Deprescribing.org Anticholinergic Burden Calculator used. Out of 291 prescribed, 28 (10%)...

Background Most elderly patients suffer from multiple diseases and are on drugs for treatment. Polypharmacy in the elderly, physiological changes with old age, pharmacokinetics pharmacodynamic effects of many drugs, newer drug prescription trends like diabetes cardiovascular disease make prescribing more difficult. There chances drug-drug interactions easily available over-the-counter (OTC) medications. To prevent irrational use there is a need analysis studies. Prescription studies will...

International Journal of Medicine and Public Health,2012,2,4,7-11.DOI:10.5530/ijmedph.2.4.2Published:Oct 2012Type:Original ArticleSelf medication pattern in rural areas Pune, IndiaYogendra Keche, Radha Yegnanarayan, Shraddha Bhoyar, Rashi Agrawal, Roshani Chavan, Priyanka Mahendrakar Yogendra Chavan Department Pharmacology, Smt Kashibai Navale Medical College Hospital, Narhe Abmegaon, Maharashtra, India-411041 Abstract:Objective: This study was carried to analyze the self Pune. Method:...

International Journal of Medicine and Public Health,2012,2,4,7-11.DOI:10.5530/ijmedph.2.4.2Published:Oct 2012Type:Original ArticleSelf medication pattern in rural areas Pune, IndiaYogendra Keche, Radha Yegnanarayan, Shraddha Bhoyar, Rashi Agrawal, Roshani Chavan, Priyanka Mahendrakar Yogendra Chavan Department Pharmacology, Smt Kashibai Navale Medical College Hospital, Narhe Abmegaon, Maharashtra, India-411041 Abstract:Objective: This study was carried to analyze the self Pune. Method:...

Adverse Drug Reactions (ADRs) can lead to significant morbidity, rarely mortality and financial burden over the patient. ADRs that be prevented considered as form of medication error sometimes. This study assessed preventability, predictability severity using different assessment scales.ADR Monitoring Centre under newly established teaching hospital in Chhattisgarh collected ADR reports from healthcare professionals during period November 2016 2018. Analysis reported was done for their...

Food and Drug Administration (FDA) approved bromocriptine mesylate, a quick release formulation, 0.8 mg tablets, as an adjunct to diet exercise improve glycemic control in adults with type 2 diabetes mellitus. Bromocriptine products were previously by the FDA for treatment of pituitary tumors Parkinson's disease. is thought act on circadian neuronal activities within hypothalamus reset abnormally elevated hypothalamic drive increased plasma glucose, triglyceride, free fatty acid levels...

<p class="Abstract">This study was conducted to observe the effect of vitamin B<sub>12</sub> supplementation on glycemic control in poorly controlled hyperhomocysteinemic type 2 diabetic patients by measuring HbA1c levels at baseline and 4 weeks. Patient having serum homocysteine more than 15 µmol/L or less 223 pg/mL were enrolled this study. One group received methylcobalamin 500 µg daily with their usual anti-diabetic therapy other only suitable drug therapy....

Background: Objective of current study was to find out self-medication pattern and awareness ADRs analgesics self-medication. Methods: II MBBS students collected the information names self-medication, dose, frequency administration, health related problem for use source about ADRs. Students also educated population with help ADR checklist. Results: Paracetamol most commonly taken as 39% persons reported paracetamol. Ibuprofen, diclofenac, paracetamol aspirin were less than WHO DDD joint...

Background : This study was carried out in various hospitals to analyze the use of rational fixed dose combinations (FDCs) Pune. Methods 279 prescriptions were evaluated this study. Information about age, sex, names all drugs prescribed by doctor/ physician, diagnosis for and adverse effects noted audit form from patients. Rationality combination is according WHO Model List Essential Drugs, 17th updated version, 2011. Results 56.98 % doctor’s containing 10.69 including two or more FDCs their...

The study was planned to evaluate the efficacy and safety of Livwin (polyherbal formulation) in acute viral hepatitis.In this study, there were 29 patients each group, receiving either (containing Ashwagandha, Arjuna, Bhumyamalaki, Daruharidra, Guduchi, Kutki Punarnava) or placebo capsules containing lactose powder (500 mg). Both drugs given orally two times a day for eight weeks followed by treatment free period four weeks. Recovery assessed noting symptomatic recovery measuring levels...

Background The elderly population differs from adults in having various physiological changes and multiple diseases, which demand the use of medications. practice polypharmacy leads to numerous harmful effects like adverse drug reactions, drug-drug interactions (DDIs), poor compliance, etc. Methodology This study collected 295 case files patients retrospectively Departments General Medicine, Cardiology Nephrology after obtaining Institute Ethics Committee approval look for potential DDIs...

Antimicrobials are frequently used in critically ill children admitted to the Paediatric Intensive Care Unit (PICU). The antimicrobial use data from Indian PICUs is limited using standard metrics such as Days of therapy (DOT). This study aimed determine baseline trend PICU a tertiary care teaching hospital Raipur district Chhattisgarh, India with goal developing facility-wide antibiotic policy and strengthening stewardship activities. active surveillance was conducted over period 18 months,...

Objective: To analyze the drug prescibed for children in some towns of Maharashtra with reference to WHO Essential Drug List Children, March 2011. Method: Data this study collected by II MBBS students at their home like Jalna, Solapur and Chipulun help prescription analysis form prepared Department Pharmacology. Rationality was evaluated as per Model Drugs Children (2011). Results: Total 46 prescriptions issued Chiplun were analyzed. 31.48 % drugs prescribed these according list Children....

Background: Staphylococcus aureus is a pathogen causing wide spectrum of infections. It has tendency for the development multidrug resistance thereby exposing selection appropriate treatment. Therefore, present study was undertaken to find out antibiotic susceptibility pattern isolated from various clinical samples in teaching tertiary hospital.Methods: Total 85 (pus, urine, sputum and blood) tested. Identification done by standard conventional microbiological methods. Antibiotic testing...

The study was planned to evaluate the efficacy and safety of Livwin (polyherbal formulation) in acute viral hepatitis. In this study, there were 29 patients each group, receiving either or placebo.  capsules contains Terminalia arjuna -100 mg, Withania somnifera - 100 mg, Phyllanthus niruri -  100 mg, Berberis aristata - 50 mg, Tinospora cordofolia - 75 mg, Picrorhiza kurroa mg,  Boerhaavia diffusa mg. Placebo contains lactose 500 Both drugs given orally, two 2 times a day for 8 weeks...

Background: Surgical site infections are associated with prolonged hospital stays and increased cost of therapy. Prophylactic use antimicrobials is to prevent the incidence postoperative wound infection. To generate data on this study was planned.Methods: The information collected in semi-structured questionnaire format from patient’s case paper. Information regarding prescribed by surgeon, including drug combinations, duration therapy, frequency administration, diagnosis for surgery...

The COVID-19 pandemic had imposed a city-level quarantine, local lockdown, and border closures for patient-level isolation to control virus spread. There is lack of studies on the health-related quality life (HRQoL) in elderly countries like India during COVID-19. After obtaining written informed consent from patients, data was recorded case record form-cum-questionnaire. assessed with help Centers disease prevention (CDC) HRQoL-14 measures, which are based general health improvement,...

Earlier identifying drug interactions may help in risk reduction elderly patients.Drug prescription data of 212 patients tertiary health care center had been analyzed for possible with investigational drugs COVID-19 treatment. Drug interaction checked from Stockley's Interaction 2019 and Martindale the Complete Reference 2017 standard reference books Pharmacology.Different types prescribed were 260 out which 68 (26.36%) category fixed-dose combinations. Around 150 (70.75%) having one or more...

Cardiovascular disease (CVD) is an important cause of morbidity and mortality in diabetic patients. As such, risk stratification essential to identify the factors CVD provide early intervention. The QRISK®3 tool, recommended by National Institute for Health Care Excellence (NICE) guidelines, has option choose patient's ethnicity, which not available other tools. However, there a paucity data regarding use this tool Indian population. Therefore, study was planned predict 10-year using...