Xiao‐Lei Sun

ORCID: 0000-0003-0066-255X
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About
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Research Areas
  • COVID-19 diagnosis using AI
  • Venous Thromboembolism Diagnosis and Management
  • Cancer-related molecular mechanisms research
  • Circular RNAs in diseases

Yantaishan Hospital
2017

Abstract This study aims to investigate the effects of microRNA‐335‐5p (miR‐335‐5p) on lower‐extremity deep vein thrombosis (LEDVT) by targeting PAI‐1 through TLR4 signaling pathway in rat models. siRNA, mimic, and inhibitor were used for transfection. The miR‐335‐5p expression was detected situ hybridization. CCK‐8 assay flow cytometry adopted detect proliferation, cell cycle, apoptosis, respectively. Scratch test Matrigel‐based tube formation effect migration ability ability. A lentivirus...

10.1002/jcb.26647 article EN Journal of Cellular Biochemistry 2017-12-26

Objective To explore the application value of Biofire Filmarry pneumonia panel (PN) in detection secondary and concomitant pathogen among critically ill patients with coronavirus disease 2019(COVID-19). Methods We consecutively included analyzed clinical data COVID-19 transferred to ICU from February April 2020 Sino-French Campus Wuhan Tongji Hospital. Samples Bronchoalveolar lavage fluid obtained by bedside bronchoscopy were sent for Filmarray PN standard culture concomitantly. compared...

10.12290/xhyxzz.20200264 article EN Xiehe yixue zazhi 2021-02-06
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