A5009563987- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Sperm and Testicular Function
- Animal Genetics and Reproduction
- Renal and related cancers
- Sexual Differentiation and Disorders
- Computational Drug Discovery Methods
- Biological and pharmacological studies of plants
- Agricultural Economics and Practices
- Alkaloids: synthesis and pharmacology
- DNA Repair Mechanisms
- Phytochemicals and Medicinal Plants
- Epigenetics and DNA Methylation
- Piperaceae Chemical and Biological Studies
- Insect and Arachnid Ecology and Behavior
- Phytochemistry and Biological Activities
- Genomic variations and chromosomal abnormalities
- Reproductive Biology and Fertility
University of Calcutta
2004-2025
Ramakrishna Mission Vivekananda Educational and Research Institute
2025
Cleveland Clinic
2004-2005
Jadavpur University
2002-2005
The recent outbreak of the novel SARS-CoV-2 across globe and absence specific drug against this virus lead scientific community to look into some alternative indigenous treatments. India as a hub Ayurvedic medicinal plants can shed light on its treatment using active bio-molecules from these plants.Keeping our herbal resources in mind, we were interested inquire whether phytochemicals Indian spices be used therapeutic agents contrast synthetic drugs.We insilico molecular docking approach...
Background: Idiopathic azoospermia is one of the most common reasons for male infertility, but little known about its genetic origins. The CDC25A gene, a meiotic core regulator, encodes phosphatase that triggers G1/S transition meiosis. It dephosphorylates and activates CDK2, as well enhances CDC2-cyclin E, CDK2-cyclin A CDK1-cyclin B complex formation, which crucial chromosome condensation progression Aim: aim this study was to identify individual variants gene make men susceptible...
Abstract Background Etiology of male infertility is intriguing and Y chromosome microdeletion within azoospermia factor (AZF) sub‐regions considered major cause. We conducted a screening for in an infertile cohort from West Bengal, India to characterize among men. Methods recruited case subjects that were categorized on the basis sperm count as (N = 63), severe oligozoospermia 38), 17) compared them with age, demography, ethnicity matched healthy proven fertile control males 84). Sequence...
The methanol fraction of the root extract Tragia involucrata was investigated for psychopharmacological activity in rodents. It produced an alteration behavioural pattern and a reduction spontaneous motility. A significant potentiation pentobarbitone-induced sleep, decrease body temperature, suppression aggressive behaviour conditioned avoidance response (CAR) were observed with fraction. These suggest that T. possesses central nervous system depressant action.
<title>Abstract</title> The full text of this preprint has been withdrawn by the authors while they make corrections to work. Therefore, do not wish work be cited as a reference. Questions should directed corresponding author.
The AZFc partial deletions of Y chromosome and lifestyle/epidemiological factors such as the use smokeless chewing tobacco (SCT) exhibit intriguing variations in their association with male infertility across population, ethnicity, genetic background. Here, a pioneering attempt has been made to elucidate interactions habits SCT consumption among participating individuals, using large epidemiological data. This screening program was conducted Bengali-speaking men West Bengal, India. We...
Abstract Background: We investigated the polymorphisms/mutations in synaptonemal complex central element protein 1 (SYCE1) and CDC25A mRNA binding (BOLL) to test whether they increase risk of azoospermia among Bengali-speaking men from West Bengal, India. Sanger's dideoxy sequencing was used genotype 140 azoospermic individuals who tested negative for Y chromosome microdeletion 120 healthy controls. In both cases controls, qRT-PCR determine expression summary SYCE1 BOLL . The perceived...
<title>Abstract</title> The Y chromosome AZF partial deletions exhibit variations in its association with male infertility across the population divides, and intriguing. Here we have analysed distinct (gr/gr, b1/b3 b2/b3) of AZFc region among 728 Bengali-speaking men compared them 264 age-matched proven-fertile control subjects. gr/gr deletion was found to be frequent azoospermic (P = 0.001) oligozoospermic 0.03) subjects, were detected significant severe-oligozoospermic 0.0405)....