A5078682053- Click Chemistry and Applications
- Multicomponent Synthesis of Heterocycles
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Chemical Synthesis and Reactions
- X-ray Diffraction in Crystallography
- Chemical Synthesis and Analysis
- Crystallization and Solubility Studies
- Synthesis and Biological Evaluation
- Nanomaterials for catalytic reactions
- Catalytic C–H Functionalization Methods
- Catalytic Cross-Coupling Reactions
- Crystallography and molecular interactions
- Synthesis and Catalytic Reactions
- Sulfur-Based Synthesis Techniques
- Electrochemical sensors and biosensors
- Molecular Sensors and Ion Detection
- Synthesis of β-Lactam Compounds
- Synthesis and Characterization of Pyrroles
- Advanced biosensing and bioanalysis techniques
- Asymmetric Hydrogenation and Catalysis
- Quinazolinone synthesis and applications
- Phenothiazines and Benzothiazines Synthesis and Activities
- Aluminum toxicity and tolerance in plants and animals
- Metal-Organic Frameworks: Synthesis and Applications
Chinese Academy of Sciences
2024
Tianjin Institute of Industrial Biotechnology
2024
K.N.Toosi University of Technology
2021-2024
Shiraz University of Medical Sciences
2020-2023
Shiraz University
2012-2020
Abstract The click chemistry is one of the most powerful C−N bond forming‐reactions towards five‐membered heterocycles. copper‐catalyzed azide‐alkyne cycloaddition (CuAAC) has widely used in discovery anti‐cancer drugs and many articles have been published this field. This review article aims to general mechanism aspects recent advances (2016–2019) for cancer therapy.
A highly active, air-stable, and versatile procedure for Buchwald–Hartwig Sharpless–Meldal C–N bond formation is reported. Under nearly solvent-free conditions using copper(II) acetate 2-phenyl-2-(4-phenyl-1<i>H</i>-1,2,3-triazol-1-yl)ethanol, a variety of N-heterocycles various cyclic noncyclic secondary amines were arylated to form N-aryl compounds in moderate excellent yields. This methodology also provides rapid access diverse 1,4-disubstituted 1,2,3-triazoles good All reactions are...
The development of novel approaches for the preparation small‐sized heterocyclic products has remained an extremely attractive but challenging proposition. Copper been known as one most applicable and significant transition metals utilized in synthesis organic products. A couple factors such high earth abundance versatile catalysis resulted growth copper‐promoted five‐membered Utilizations making coins electrical equipment express importance copper, well. Here, a comprehensive overview...
Copper(I) oxide nanoparticles (CONPs) catalyze multicomponent coupling/cycloisomerization reactions between various 2-hydroxybenzaldehydes, secondary amines, and nonactivated alkynes to give 2,3-disubstituted 1-benzofurans. All are carried out under solvent- ligand-free conditions at 100 °C in air. The combination of copper-catalyzed C–H activation an O-annulation process is essential for this transformation. This methodology provides rapid access substituted 1-benzofurans good excellent...
An air‐stable, highly active and versatile method for C─N bond forming reactions is reported. Under mild conditions using a reusable support‐free Cu(II)–salen complex, structurally diverse N ‐aryl‐substituted compounds were obtained via direct reaction of HN‐heterocycles with aryl iodides or three‐component 2‐bromobenzaldehyde, aniline derivatives sodium azide in good to excellent yields. benzimidazole was also performed the presence catalyst under ambient conditions. A series hybrid...
A novel and efficient nanocatalyst consisting of benzimidazole‐salen Cu(II) complex on surface‐modified silica (BS‐Cu(II)@SiO 2 ) was prepared. The heterogeneous characterized by FESEM, TEM, EDX, FT‐IR, XRD, ICP, TGA. used for the one‐pot synthesis some target hybrid molecules. An four component C–H bond activation/[3 + 2] cycloaddition condensation/cyclization/aromatization sequence toward triazole‐benzimidazole derivatives is disclosed. This methodology provides a general rapid synthetic...
The synthesis, characterization and catalytic activity of a Cu(II) complex derived from 2‐oxoquinoline‐3‐carbaldehyde Schiff base supported on amino‐functionalized silica are reported. 3‐(1 H ‐Benzo[ d ]imidazol‐2‐yl)quinolines containing piperidine, morpholine phenylpiperazine skeletons at the C‐2 position were formed in good to excellent yields via one‐pot reaction 2‐chloroquinoline‐3‐carbaldehyde, benzene‐1,2‐diamines secondary amines presence nanocatalyst under mild conditions. Moreover,...
A highly efficient, simple and environmentally friendly synthesis of 3-arylquinolines has been developed in the presence Al 2 O 3 /MeSO H via one-pot reaction anilines styrene oxide. This methodology provides very rapid access to good excellent yields under solvent-free conditions at room temperature air.
The development of a product that has simultaneous wound healing, anti‐inflammatory, and antimicrobial properties is desirable for healing medicine. In this study, glycine–histidine–lysine (GHK) peptide as skin repair accelerator was coupled to L ‐carnitine with antibacterial anti‐inflammatory investigate its new in nanoparticle (NP) platform. conjugate synthesized by solid‐phase synthesis method Fmoc chemistry, purified preparative HPLC, identified ESI‐Mass technique. then loaded into PLGA...