A5032948193- Advanced NMR Techniques and Applications
- Solid-state spectroscopy and crystallography
- NMR spectroscopy and applications
- Advancements in Battery Materials
- Advanced Battery Materials and Technologies
- Electron Spin Resonance Studies
- Protein Structure and Dynamics
- Lipid Membrane Structure and Behavior
- Advanced MRI Techniques and Applications
- Antimicrobial Peptides and Activities
- Bacteriophages and microbial interactions
- RNA and protein synthesis mechanisms
- Advanced Battery Technologies Research
- Zeolite Catalysis and Synthesis
- Metal-Organic Frameworks: Synthesis and Applications
- Acoustic Wave Resonator Technologies
- X-ray Diffraction in Crystallography
- Crystal Structures and Properties
- Chemical Synthesis and Characterization
- Crystallization and Solubility Studies
- DNA and Nucleic Acid Chemistry
- Enzyme Structure and Function
- Alzheimer's disease research and treatments
- Biochemical and Structural Characterization
- Tuberculosis Research and Epidemiology
National High Magnetic Field Laboratory
2016-2025
Florida State University
2016-2025
ORCID
2021
Tallahassee Orthopedic Clinic
2014-2020
Pacific Lutheran University
2009
Hamilton College
2009
University of Windsor
2008
Mercer University
2003
Florida Agricultural and Mechanical University
2002-2003
Wuhan Institute of Physics and Mathematics
1992-2003
Abstract Air-stability is one of the most important considerations for practical application electrode materials in energy-harvesting/storage devices, ranging from solar cells to rechargeable batteries. The promising P2-layered sodium transition metal oxides (P2-Na x TmO 2 ) often suffer structural/chemical transformations when contacted with moist air. However, these elaborate transitions and evaluation rules towards air-stable P2-Na have not yet been clearly elucidated. Herein, taking 0.67...
This review summarizes the history and critical working mechanisms of Li-rich oxides with a special focus on anionic redox reactions.
Abstract Layered transition metal oxides are the most important cathode materials for Li/Na/K ion batteries. Suppressing undesirable phase transformations during charge-discharge processes is a critical and fundamental challenge towards rational design of high-performance layered oxide cathodes. Here we report shale-like Na x MnO 2 (S-NMO) electrode that derived from simple but effective water-mediated strategy. This strategy expands + layer spacings P2-type 0.67 transforms particles into...
P2-type sodium nickel manganese oxide-based cathode materials with higher energy densities are prime candidates for applications in rechargeable ion batteries. A systematic study combining situ high X-ray diffraction (HEXRD), ex absorption fine spectroscopy (XAFS), transmission electron microscopy (TEM), and solid-state nuclear magnetic resonance (SS-NMR) techniques was carried out to gain a deep insight into the structural evolution of P2–Na0.66Ni0.33–xZnxMn0.67O2 (x = 0, 0.07) during...
Advanced spectroscopy methods quantitatively elucidate the failure process of lithium metal batteries.
The performance of all-solid-state lithium metal batteries (SSLMBs) is affected by the presence electrochemically inactive (i.e., electronically and/or ionically disconnected) and solid electrolyte interphase (SEI), which are jointly termed lithium. However, differentiation quantification during cycling challenging, their lack limits fundamental understanding SSLMBs failure mechanisms. To shed some light on these crucial aspects, here, we propose operando nuclear magnetic resonance (NMR)...
The heart of the H+ conductance mechanism in homotetrameric M2 channel from influenza A is a set four histidine side chains. Here, we show that protonation third these imidazoles coincides with acid activation this transmembrane and that, at physiological pH, closed by two imidazole-imidazolium dimers, each sharing low-barrier hydrogen bond. This unique construct succeeds distributing pair charges over rings many atoms low dielectric environment to minimize charge repulsion. These dimers...
The development of highly reversible multielectron reaction per redox center in sodium super ionic conductor-structured cathode materials is desired to improve the energy density sodium-ion batteries. Here, we investigated more than one-electron storage Na Na3VCr(PO4)3. Combining a series advanced characterization techniques such as ex situ 51V solid-state nuclear magnetic resonance, X-ray absorption near-edge structure, and diffraction, reveal that V3+/V4+ V4+/V5+ couples can be accessed,...
The cubic garnet-type solid electrolyte Li7La3Zr2O12 with aliovalent doping exhibits a high ionic conductivity, reaching up to ∼10–3 S/cm at room temperature. Fully understanding the Li+ transport mechanism including mobility different sites is key topic in this field, and Li7–2x–3yAlyLa3Zr2–xWxO12 (0 ≤ x 1) are selected as target electrolytes. X-ray neutron diffraction well ac impedance results show that low amount of substitution Zr W does not obviously affect crystal structure activation...
Host‐defense peptides (HDPs) feature evolution‐tested potency against life‐threatening pathogens. While piscidin 1 (p1) and 3 (p3) are homologous potent fish HDPs, only p1 is strongly membranolytic. Here, we hypothesize that another mechanism imparts p3 strong potency. We demonstrate the N‐termini of both coordinate Cu 2+ p3‐Cu cleaves isolated DNA at a rate on par with free but significantly faster than p1‐Cu. On planktonic bacteria, more antimicrobial features copper‐dependent cleavage....
Na2 FePO4 F is a promising cathode material for Na-ion batteries owing to its relatively high discharge voltage and excellent cycling performance. Now, the long- short-range structural evolution of during studied by in situ high-energy X-ray diffraction (XRD), ex solid-state nuclear magnetic resonance (NMR), first-principles DFT calculations. calculations suggest that intermediate phase, Na1.5 F, adopts space group P21 /c, which subgroup (P21 /b11, No. 14) Pbcn (No. 60), starting this...
The cubic garnet-type solid electrolyte Li<sub>7</sub>La<sub>3</sub>Zr<sub>2</sub>O<sub>12</sub> with aliovalent doping exhibits a high ionic conductivity.
Abstract Substitution of liquid electrolyte with solid‐state electrolytes (SSEs) has emerged as a very urgent and challenging research area rechargeable batteries. NASICON (Na 3 Zr 2 Si PO 12 ) is one the most potential SSEs for Na‐ion batteries due to its high ionic conductivity low thermal expansion. It proven that can be improved 10 −3 S cm −1 by Sc‐doping, which mechanism, however, not been fully understood. Herein, series Na 3+x Sc x 2−x (0 ≤ 0.5) are prepared. To gain deep insight into...
Abstract An approach to spinning sideband (SSB) separation of protonated and non‐protonated carbons in slow conditions via dipolar dephasing is proposed. This method offers two features: SSB spectral simplification, which greatly reduces the overlaps encountered a usual spectrum, distinction overlapped resonances for carbons. The 13 C chemical shift anisotropies 20 amino acids as polycrystalline powdered solids were completely measured with intensity analyses an application suggested approach.
Solid-state 35Cl NMR (SSNMR) spectroscopy is shown to be a useful probe of structure and polymorphism in HCl pharmaceuticals, which constitute ca. 50% known pharmaceutical salts. Chlorine spectra, single-crystal powder X-ray diffraction data, complementary ab initio calculations are presented for series local anesthetic (LA) pharmaceuticals some their polymorphs. MAS SSNMR spectra acquired at 21.1 T stationary samples 9.4 allow extraction chlorine electric field gradient (EFG) chemical shift...
Validation: Membrane protein structures are sensitive to the environment used for structural characterization. NMR spectra of full-length M2 proton channel from influenza A were measured directly in E. coli membranes and compared synthetic lipid bilayers. The results demonstrate that these bilayers provide a native-like membrane environment.
The feasibility of using solid-state magic-angle-spinning NMR spectroscopy for in situ structural characterization the LR11 (sorLA) transmembrane domain (TM) native Escherichia coli membranes is presented. interacts with human amyloid precursor protein (APP), a central player pathology Alzheimer's disease. background signals from E. lipids and membrane proteins had only minor effects on TM resonances. Approximately 50% residues were assigned by (13)C PARIS data. These assignments allowed...