A5101567439- Salivary Gland Tumors Diagnosis and Treatment
- Phytoplasmas and Hemiptera pathogens
- MicroRNA in disease regulation
- Genomics and Chromatin Dynamics
- CNS Lymphoma Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Lymphoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- PI3K/AKT/mTOR signaling in cancer
- Viral-associated cancers and disorders
- Glycosylation and Glycoproteins Research
- Genetic Associations and Epidemiology
- Dental Radiography and Imaging
- Genetic factors in colorectal cancer
- Protein Kinase Regulation and GTPase Signaling
- Forensic Anthropology and Bioarchaeology Studies
- Oral microbiology and periodontitis research
- RNA modifications and cancer
- Endodontics and Root Canal Treatments
- Advanced Glycation End Products research
- Head and Neck Cancer Studies
- TGF-β signaling in diseases
- Orthodontics and Dentofacial Orthopedics
- CRISPR and Genetic Engineering
- DNA Repair Mechanisms
Soochow University
2014-2024
Second Affiliated Hospital of Soochow University
2014-2024
First Affiliated Hospital of Soochow University
2014
Chinese Academy of Medical Sciences & Peking Union Medical College
2005-2014
Xi'an Jiaotong University
2012
University of Yamanashi
2012
Peking Union Medical College Hospital
2005
Saga Medical School Hospital
1992
Background Breast cancer 2 ( BRCA2 ) is an important breast cancer-susceptibility gene. Promoter polymorphisms in may affect its transcription and be associated with prognosis. Methods We identified five of the promoter region by silico searching direct sequencing: -254A/G (rs3092989), -908A/G (rs206117), -1134A/G (rs206115), -1144C/T (rs206116), -1260CTTAGA/-(rs3072036). The -908A/G, -1134A/G, -1144C/T, -1260CTTAGA/- were genotyped sequencing 491 patients, polymorphism was Sequenom. Results...
Salivary adenoid cystic carcinoma is one of the most common malignancies head and neck. The lysosome-associated protein transmembrane-4β gene (LAPTM4B) a novel oncogene that has been found overexpressed in number clinically aggressive cancers. This study aimed to investigate expression LAPTM4B-35 normal salivary gland carcinoma, relatively indolent malignancy, explore its clinicopathological significance this malignancy. By immunohistochemical analysis, was evaluated 106 cancer tissues,...
We studied the effects of glycated lipoproteins low-and high-density (LDL and HDL) on platelets vascular endothelial cells. After pretreatment for 5 minutes at 37°C, thrombininduced synthesis thromboxane B2 in washed was significantly increased by LDL as compared with native (198.9 ± 16.2 vs 90.3 29.4ng/109 platelets, n = 8, p < 0.01). Platelet aggregation also LDL. treatment platelet-rich plasma hours these values were suppressed HDL control (buffer), but not HDL. Abnormalities release...
Oral squamous cell carcinoma (OSCC) had the poor prognosis. miR-155 was involved in some diseases. However, whether BMSCs with high expression affect proliferation and metastasis of OSCC is unclear. Our study aims to assess BMSCs’ effect on cells. level tumor tissues analyzed. were transfected followed by analysis MTT assay, apoptosis migration, MMP-9 ELISA PTEN12 level. In tissue, significantly increased ( P <0.05). Co-culture cells could promote reduced apoptotic activity, migration...
Abstract Mucoepidermoid carcinoma (MEC) is the most common type of malignancy affecting salivary glands. Previous studies have suggested involvement lysosome-associated transmembrane protein 4β (LAPTM4B) in development and progression various tumors. However, its specific role MEC has not been fully elucidated. In this study, we aimed to investigate expression LAPTM4B-35 tissue samples explore association with clinicopathological features. Additionally, sought inhibit an cell line assess...