A5074386861- Kawasaki Disease and Coronary Complications
- Coronary Artery Anomalies
- Mechanical Circulatory Support Devices
- Hepatitis C virus research
- Cardiac Structural Anomalies and Repair
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Liver Disease Diagnosis and Treatment
- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Hepatitis B Virus Studies
- Cancer, Hypoxia, and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiac Arrhythmias and Treatments
- Advancements in Transdermal Drug Delivery
- Aortic Disease and Treatment Approaches
- Virus-based gene therapy research
- Advanced Fiber Optic Sensors
- High voltage insulation and dielectric phenomena
- Cardiovascular Disease and Adiposity
- Protease and Inhibitor Mechanisms
- Influenza Virus Research Studies
- Supramolecular Self-Assembly in Materials
- Pneumonia and Respiratory Infections
- Lipoproteins and Cardiovascular Health
- Fibroblast Growth Factor Research
Children's Hospital of Chongqing Medical University
2021-2025
Chongqing Medical University
2020-2025
Kingmed Diagnostics
2025
China International Science and Technology Cooperation
2021-2024
Guangzhou Medical University
2021-2023
First Affiliated Hospital of Guangzhou Medical University
2021-2023
State Key Laboratory of Respiratory Disease
2021-2023
National Clinical Research
2022-2023
Cardiovascular Research Center
2023
Chinese PLA General Hospital
2022
Section:ChooseTop of pageAbstract <<Study DesignMethodsResultsDiscussionReferencesCITING ARTICLES
We demonstrate the room-temperature control of magnetization reversal with an electric field in epitaxial nanostructure consisting ferrimagnetic nanopillars embedded a ferroelectric matrix. This was achieved by combining weak, uniform magnetic switching to selectively switch pillars only one configuration. On basis these experimental results, we propose use assist recording multiferroic systems high perpendicular anisotropy.
Background Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease with few treatment options. The poor success in developing anti-IPF strategies has impelled researchers to reconsider the importance of choice animal model and assessment methodologies. Currently, it still not settled whether bleomycin-induced mouse finally returns resolution. Methods This study aimed follow dynamic fibrotic features bleomycin-treated lungs over extended durations through combination latest technologies...
Staphylococcal enterotoxin B (SEB) produced by the Staphylococcus aureus bacteriumis most commonly associated with food poisoning and is known to also cause toxic shock syndrome. Currently, no approved vaccine or specific drug available treat SEB intoxication. In this study, we fabricated dissolving microneedles (MNs) loaded recombinant (rSEB) protein, evaluated its characteristics, including dissolution profile, protein particle size, insertion depth, antigen retention time in vivo, skin...
Cross-sectional studies suggest insulin resistance is strongly associated with hepatic steatosis and fibrosis in patients chronic hepatitis C (CHC), which might affect the efficacy of antiviral therapy. Aim To investigate retrospectively impact on treatment response Chinese genotype 1 CHC receiving a 24-week course therapy peginterferon alpha-2b/ribavirin.A total 133 biopsy-proven were enrolled for analyses. Insulin was evaluated by homeostasis model assessment (HOMA-IR). Hepatic graded...
Rationale: Mass vaccination, low cost of immunoglobulins, and new drugs led to the emergence new, unusual patterns hepatitis B serum markers. This study reported a rare case with all 5 positive markers, including HBsAg, HBsAb, HBeAg, HBeAb, HBcAb. Patient concerns: A 30-year-old female patient was admitted due abnormal liver function. The markers were (+), After antiviral therapy, she discharged normal function decreased virus-DNA levels, but still positive. Regular follow-up conducted every...
Accumulating evidence indicates associations between ambient air pollution and Kawasaki disease (KD), but the results remain inconsistent. This systematic review meta-analysis aimed to comprehensively summarize current on effects of pollutants KD. The PubMed, Web Science, Embase, Scopus databases were searched up January 18, 2025 for studies investigating A fixed- or random-effects model was used calculate pooled ORs with 95% CIs an increase in pollutant concentration 10 μg/m3. risk bias...
There are no studies on the burden of ischemic heart disease (IHD) among women childbearing age (WCBA) in China. This study aims to describe IHD WCBA China from 1990 2021, predict trends over next 15 years, and identify contributing factors associated with IHD-related deaths. The data was extracted Global Burden Disease Database 2021. Direct age-standardized method used estimate (AS) prevalence rate (ASPR), mortality (ASMR), incidence (ASIR), disability-adjusted life years (ASDR) WCBA....
Andrographolide (Andro), a diterpenoid extracted from Andrographis paniculata, has been shown to attenuate pulmonary fibrosis in rodents; however, the potential mechanisms remain largely unclear. This study investigated whether and how Andro alleviates bleomycin (BLM)-induced NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome activation epithelial-mesenchymal transition (EMT) lung epithelial cells.The vivo effects of were evaluated rat model BLM-induced fibrosis. The...
<b><i>Background:</i></b> Basic fibroblast growth factor (bFGF) has been increasingly investigated due to its neuroprotection in neurodegenerative disorders. Because there are still no cures for any of these disorders, it is crucial identify new therapeutic targets and screen potential drugs. The increased phosphorylation tau at Ser<sup>396</sup> leads intracellular accumulation, which forms neurofibrillary tangles Parkinson's disease (PD). In this study,...
Reliably prediction models for coronary artery abnormalities (CAA) in children aged >5 years with Kawasaki disease (KD) are still lacking. This study aimed to develop a nomogram model predicting CAA at 4 8 weeks of illness KD older than 5 years.
Elevated plasma levels of C-reactive protein (CRP) are associated with increased risk cardiovascular disease. CRP immunoreactive is also detected in the lesions atherosclerosis. However, it not known whether contents atherosclerotic initiation and progression To examine this hypothesis, we investigated different types rabbits fed a cholesterol-rich diet for 6, 12, 16, 28 weeks examined their relationship CRP. We measured aortic area, macrophages, smooth muscle cells along lesions....
Disabilities triggered by neurodegeneration mainly result in mortality the elderly, and patients with neurodegenerative disease also display deficits olfactory function. Therefore drug distribution to brain through intranasal administration has become one of most difficult challenges treatment central nervous system (CNS) diseases. TAT-human acidic fibroblast growth factor (HaFGF) is a new fused protein retaining neuroprotective activities HaFGF, promising prospect TAT (a cell-penetrating...
Abstract Background Kawasaki disease (KD) is an acute systemic vasculitis of unknown etiology that predominantly affects children, and no specific diagnostic biomarkers for KD are available. Platelet-derived growth factor CC (PDGF-CC) a peptide with angiogenic properties has been amply demonstrated to play critical role in the cardiovascular system. This study aimed investigate serum expression PDGF-CC children evaluate ability diagnose KD. Methods A total 96 subjects, including 59 patients,...
Objectives: The frontal sinus has the most complex and variable drainage routes of all paranasal regions. goal this study was to identify these anatomical factors inflammation areas relating chronic sinusitis by comparing radiological presentations in patients with without sinusitis. Methods: All adult rhinosinusitis who had received computed tomography (CT) scans nasal cavities sinuses between October 2010 September 2011. Logistic regression analysis used compare distribution various recess...
Objectives: To evaluate the causes and risk factors of unplanned surgery after transcatheter closure ventricular septal defect (VSD) in children. Methods: A total 773 patients with VSD who had devices released between January 2013 December 2018 our institution were retrospectively reviewed. Univariate multivariate analyses used to identify for surgery. Results: Twenty four (3.1%) underwent VSD. The most common cause was new-onset or worsening aortic regurgitation (14/24; 58.3%), followed by...
Background: Arrhythmia is the most common complication after transcatheter closure of a ventricular septal defect (VSD). However, effects postprocedural left anterior fascicular block are not clear. This study presents clinical characteristics, prognosis, and related risk factors VSD in children. Methods: The follow-up data patients Heart Center Children's Hospital Chongqing Medical University from June 2009 to October 2018 were reviewed. And 30 cases eligible out all 1,371 cases. Results:...