A5014118038- Advanced MRI Techniques and Applications
- Cardiac Imaging and Diagnostics
- Electron Spin Resonance Studies
- Lanthanide and Transition Metal Complexes
- Atomic and Subatomic Physics Research
- Advanced X-ray and CT Imaging
- Cerebrovascular and Carotid Artery Diseases
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Advanced NMR Techniques and Applications
- Cardiac Structural Anomalies and Repair
- Radiation Dose and Imaging
- MRI in cancer diagnosis
- Medical Imaging Techniques and Applications
- Cardiovascular Issues in Pregnancy
- NMR spectroscopy and applications
- History of Medicine Studies
- Intracranial Aneurysms: Treatment and Complications
- COVID-19 and healthcare impacts
- Cardiac Valve Diseases and Treatments
- Nitric Oxide and Endothelin Effects
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Gastrointestinal disorders and treatments
- Nuclear Physics and Applications
Scripps Clinic
2017-2025
Scripps Health
2021-2024
Scripps (United States)
2024
Scripps Institution of Oceanography
2024
Scripps Clinic Medical Group
2019-2021
Rutgers, The State University of New Jersey
1994
Scripps Memorial Hospital
1990-1993
University of California, San Diego
1990
LDS Hospital
1987
Centre for Medical Systems Biology
1987
Acute myocardial infarctions were produced in 11 dogs by ligation of the left anterior descending coronary artery. Twenty-four hours after ligation, 0.35 millimoles per kilogram Gd-DTPA was injected intravenously, followed cardiectomy either 90 seconds (3 dogs) or 5 minutes (5 later. The remaining 3 had without injection at 24 occlusion. that did not receive longer T1 and T2 relaxation times infarcted myocardium than normal myocardium, as measured a 10.7-MHz magnetic resonance (MR)...
A piperidinyl nitroxide stable free radical derivative, TES, was tested as an NMR contrast enhancer of renal structures in normal animals and with experimentally induced unilateral ischemia, vascular congestion, hydronephrosis. Physiologic measurements indicated that TES is rapidly excreted the urine a clearance rate equal to glomerular filtration rate. Because compound strongly paramagnetic, it increases observable intensity within kidneys relatively low doses (0.04 0.9 g/kg). TES-enhanced...
Tissue deposits of hemosiderin, a paramagnetic iron-protein complex, resulted in marked abnormalities magnetic resonance (MR) spin-echo signal intensity within the viscera three children with transfusional hemosiderosis and thalassemia major. In all patients liver bone marrow demonstrated abnormally low intensities kidneys muscles had high intensities. These observations correlate vitro MR ferric (Fe+3) solutions, which concentrations salts greater than 20 mmol yielded less 15 higher did...
Imaging by nuclear magnetic resonance (NMR) techniques has been shown to provide high-contrast resolution between soft tissues and characterization of normal pathologic differences in relaxation times. The current study was designed determine whether electrocardiogram (ECG)-gated NMR imaging the canine heart vivo could distinguish from infarcted myocardium without use intravenous paramagnetic contrast agents. Seven dogs were studied ECG-gated (spin-echo technique) with a 0.35 Tesla...
By varying slice-selective gradients in successive data acquisitions, the first vitro measurements of molecular self-diffusion coefficients were performed a magnetic resonance imager at 0.35 Tesla. Reasonably accurate found by MRI method comparison with 2.3 T NMR spectrometer on same samples, and to reported literature values. Thus, addition T1, T2, mobile proton density, flow velocity, susceptibility, chemical shift, are now added list biophysical parameters measurable imaging noninvasive...
Two dilute oral iron solutions, made from commonly available nonprescription dietary supplements, were found to enhance the gastrointestinal tract in nuclear magnetic resonance imaging of live rats and one human volunteer. The paramagnetic pharmacologic properties ferric ammonium citrate more favorable than those ferrous sulfate heptahydrate. solutions shorten T1 T2 relaxation times water protons contrast media-filled tract, producing easily observable change NMR intensity. Because these are...
Prospective evaluation of extracranial carotid stenosis: MR angiography with maximum-intensity projections and multiplanar reformation compared conventional angiography.J K De Marco, G M Nesbit, E Wesbey D RichardsonAudio Available | Share
Background: Coronary plaque features are imaging biomarkers of cardiovascular risk, but less is known about sex-specific patterns in their prognostic value. This study aimed to define sex differences the coronary atherosclerotic phenotypes assessed by artificial intelligence-based quantitative computed tomography (AI-QCT) and associated risk major adverse events (MACE). Methods: Global multicenter registry (CONFIRM2) including symptomatic patients with suspicion CAD referred for CTA. AI-QCT...
A case of Horner syndrome occurring secondary to the high insertion a chest tube is reported. from this cause can easily be avoided. The tip should kept at or below third posterior rib unless clinical situation dictates otherwise.
The reduced T2 (spin-spin) relaxation times (T2obs less than 200 ms) measured on pure fluids our 0.35T magnetic resonance imagers stimulated an investigation into this phenomenon. cause for the short T2obs of was found to be translational molecular self-diffusion hydrogen nuclei through pulsed slice-selective gradient in imagers. Similar reductions biological tissue were also attributed self-diffusion.
The capability of magnetic resonance (MR) imaging for detecting aortic, iliac, and femoral stenoses occlusions was evaluated. Multisection spin-echo studies at 0.35 tesla were obtained the infrarenal aorta to bifurcation in 24 patients, all whom had undergone intraarterial angiography within 14 days imaging. Transaxial MR images compared with angiograms. Arterial these vessels detected by correlated angiographic findings 91% instances. Protrusional atherosclerotic plaques aortoiliac region...
Magnetic resonance (MR) imaging was performed in 10 children with intrathoracic disease. Entities imaged included mediastinal lymphoma and neuroblastoma, pulmonary metastases from hepatoblastoma osteogenic sarcoma, hemorrhagic pleural effusion, nonmalignant disease such as abscess, cystic fibrosis, bronchogenic cyst. MR particularly valuable delineating parenchymal masses adjacent vascular structures without the need for contrast material enhancement. However, insensitive to lesion...
The effects of an intravenously administered nitroxyl spin label (PCA) on the magnetic resonance imaging (MRI) appearance and relaxation times acute canine myocardial infarctions were studied. Twenty-four hours after ligation left anterior descending coronary artery (LAD), animals either sacrificed immediately (three dogs) or injected with 3.0 mmol/kg PCA prior to sacrifice (six dogs). group dogs at 5 minutes postinjection 15 Magnetic (0.35 T) using spin-echo techniques demonstrated high...
Coronary CT angiography (CCTA) and contrast-enhanced thoracic (CECT) are distinctly different diagnostic procedures that involve intravenous of the chest. The technical component these is reimbursed at same rate by Centers for Medicare Medicaid Services (CMS). This study tests hypothesis direct costs performing exams significantly different.Direct both were measured using a time-driven activity-based costing (TDABC) model. segmented into four phases: preparation, scanning, post-scan...