A5047057178- Computational Drug Discovery Methods
- Education and Digital Technologies
- Protein Structure and Dynamics
- Science and Education Research
- Genetics, Bioinformatics, and Biomedical Research
- Cell Adhesion Molecules Research
- Cancer therapeutics and mechanisms
- Receptor Mechanisms and Signaling
- Bioinformatics and Genomic Networks
- Immunotherapy and Immune Responses
- Computational Physics and Python Applications
- Glycosylation and Glycoproteins Research
State University of Norte Fluminense
2018-2022
The COVID-19 pandemic has had an unprecedented impact on the global economy and public health. Its etiologic agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly transmissible, pathogenic a rapid spread. Currently, increase in number of new confirmed cases been slowed down due to vaccination some regions world. Still, rise variants influenced detection additional waves rising that countries have experienced. Since virus replication cycle composed many distinct...
Integrins constitute key molecular factors interfering in cell adhesion, proliferation, and migration. The α6β1 integrin is the primary receptor of laminin family, it known that laminin-binding plays a notorious role critical physiological processes such as inflammation, cancer, metastasis. Tumor-associated macrophages are involved regulation tumor microenvironment, progression, To downmodulate J774A1 macrophages' adhesion migration to laminin, cyclic peptide (A9a) was designed interact with...