- Renal Transplantation Outcomes and Treatments
- Clinical Nutrition and Gastroenterology
- Estrogen and related hormone effects
- Organ Transplantation Techniques and Outcomes
- Mechanical Circulatory Support Devices
- COVID-19 Clinical Research Studies
- Polyomavirus and related diseases
- Atrial Fibrillation Management and Outcomes
- Cytomegalovirus and herpesvirus research
- Transplantation: Methods and Outcomes
- Phytoestrogen effects and research
- Tracheal and airway disorders
- COVID-19 and healthcare impacts
- Long-Term Effects of COVID-19
- Prostate Cancer Treatment and Research
- Head and Neck Surgical Oncology
- Pharmacogenetics and Drug Metabolism
- Viral Infections and Immunology Research
- Heart Failure Treatment and Management
- Cancer, Lipids, and Metabolism
- Tannin, Tannase and Anticancer Activities
- Drug Transport and Resistance Mechanisms
- Heparin-Induced Thrombocytopenia and Thrombosis
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
Methodist Hospital
2020-2025
Indiana University – Purdue University Indianapolis
2014-2022
Indiana University School of Medicine
2015-2020
Indiana University Hospital
2017-2019
Cedars-Sinai Medical Center
2018
Mayo Clinic Hospital
2016
Development Fund
2015
Sabbatsberg Hospital
1963
Cytomegalovirus (CMV) infection is the most prevalent infectious complication after solid organ transplantation, and recipients of isolated intestinal transplantation (IIT)/multivisceral (MVT) are among those at highest risk. Limited clinical data exist regarding CMV IIT/MVT. The aim this study to analyze risk factors for posttransplant assess efficacy validity our prophylaxis treatment regimens in transplantation.Medical records 210 IIT/MVT patients were retrospectively reviewed....
Intestinal graft dysfunction is sometimes irreversible and requires allograft enterectomy with or without retransplantation. There no comprehensive assessment of regarding indications outcomes. The aim this study was to evaluate management patients intestinal failure special reference outcomes the procedure's validity as a bridge retransplantation.Graft patient survivals, reason for failure, rejection episodes were evaluated in 221 recipients (primary transplantation [n = 201],...
We present the first reported case of left ventricular assist device (LVAD) pump thrombosis in setting coronavirus pandemic. describe clinical features which helped to differentiate disease 19 (COVID-19) from LVAD thrombosis. The patient is 56-year-old female supported by destination therapy. She was originally implanted with a HeartMate II 2015 and underwent two exchanges 2017 2019 for thrombosis, despite medication adherence. Shortly after routine lab work revealed near doubling her...
In a material of 29 experimental subjects, bromsulfalein infusions have been given with different doses, and from the data capacity liver to excrete bromsulfalein, so-called hepatic mass, hm or Tm, has calculated according 3 methods. It is shown that all methods calculation suffer systematic errors, so hm-value not real import was expected.
Background: Recently, peritransplant absolute lymphocyte count (ALC) has been identified as a prognostic factor after liver transplantation. Lymphopenia is associated with suboptimal conditions such frailty, malnutrition and sepsis. The aim of this study was to investigate the impact ALC on outcome isolated intestine/multivisceral transplantation (IIT/MVT). Methods: Between 2004 2012, patients (>15yo) who underwent IIT/MVT were reviewed. Pre posttransplant (at 3, 6, 12 months) evaluated for...
Background: Total parenteral nutrition (TPN) free status is one of the goals in isolated intestine/multivisceral transplantation (IIT/MVT), whereas some patients require long-term posttransplant TPN because malfunction transplant intestine. This issue has not been fully investigated. Methods: Between 2003 and 2012, 141 (>15yo) who underwent IIT/MVT were reviewed. Posttransplant dependent was defined as requirement for 90 days or longer first year. Patients survived during year included this...
The emphasis of mammographic breast screening is to detect small invasive cancers at a time in their natural history when early detection and treatment will reduce significantly the risk death.However, cannot be absolutely specific its approach detects wide spectrum cancer, ranging from microfocal low-grade ductal carcinoma situ large highgrade cancer.It well recognized that many lowgrade, special identified have an excellent prognosis but may so indolent they would never presented...
Pump thrombosis is a devastating complication of left ventricular assist device implantation as it increases the risk mortality and morbidity. Early effective treatment important to prevent progression clot avoid surgical need for pump exchange or heart transplant. The current strategies intensifying anticoagulation therapy are not consistently carry significant bleeding risks. Cangrelor new pharmacological agent that has been utilized an antiplatelet in several cardiac procedures. In this...
Abstract Background In lung transplant recipients, respiratory tract infections are associated with faster progression through stages of bronchiolitis obliterans syndrome and mortality. Common causative pathogens for (RTIs) include non-fermenting gram-negative bacilli (NFGNB). Data to guide optimal treatment durations NFGNB RTIs in this population limited. Methods This was a single-center, retrospective, cohort study adult recipients who received systemic antibiotic caused by NFNGB had at...
Aims: The presence of cerbB-2 oncoprotein is said to predict failure respond endocrine therapy in breast cancer (particularly tamoxifen). aim the study was determine whether effect oestrogen deprivation (by stopping HRT) on related expression. Methods and study: We identified 129 women who were HRT at time diagnosis by core biopsy. Out women, 114 stopped 15 continued till surgery. Ki67 (a marker cell proliferation), progesterone receptor (PR), ER (oestrogen receptor) cyclin D1 cycle inducer)...