MacKenzie Jacobs

ORCID: 0000-0003-0113-1224
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About
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Research Areas
  • Plant-Microbe Interactions and Immunity
  • Berry genetics and cultivation research
  • Plant Pathogens and Fungal Diseases
  • Legume Nitrogen Fixing Symbiosis
  • Horticultural and Viticultural Research
  • Plant Physiology and Cultivation Studies
  • Bacillus and Francisella bacterial research
  • Plant Gene Expression Analysis
  • Insect and Pesticide Research
  • Plant Molecular Biology Research
  • Toxin Mechanisms and Immunotoxins
  • Insect Pest Control Strategies
  • Genetic Mapping and Diversity in Plants and Animals
  • Genomics and Phylogenetic Studies
  • Insect Resistance and Genetics
  • Viral Infections and Outbreaks Research
  • Plant Reproductive Biology
  • Yeasts and Rust Fungi Studies
  • Soybean genetics and cultivation
  • Mycotoxins in Agriculture and Food

Michigan State University
2022-2024

West Liberty University
2017-2022

Abstract The genus Vaccinium L. (Ericaceae) contains a wide diversity of culturally and economically important berry crop species. Consumer demand scientific research in blueberry (Vaccinium spp.) cranberry macrocarpon) have increased worldwide over the crops’ relatively short domestication history (~100 years). Other species, including bilberry myrtillus), lingonberry vitis-idaea), ohelo reticulatum) are largely still harvested from wild but with improvement efforts underway. Here, we...

10.1093/hr/uhac083 article EN cc-by Horticulture Research 2022-01-01

Domestication of cranberry and blueberry began in the United States early 1800s 1900s, respectively, part owing to their flavors health-promoting benefits are now cultivated consumed worldwide. The industry continues face a wide variety production challenges (e.g. disease pressures), as well demand for higher-yielding cultivars with improved fruit quality characteristics. Unfortunately, molecular tools help guide breeding efforts these species have been relatively limited compared those...

10.1093/hr/uhad202 article EN cc-by Horticulture Research 2023-10-10

Acylsugars are defensive, trichome-synthesized sugar esters produced in plants across the Solanaceae (nightshade) family. Although assembled from simple metabolites and synthesized by a relatively short core biosynthetic pathway, tremendous within- across-species acylsugar structural variation is documented To advance our understanding of diversity synthesis acylsugars within Nicotiana genus, trichome extracts were profiled genus coupled with transcriptomics-guided enzyme discovery vivo...

10.1093/plphys/kiac192 article EN PLANT PHYSIOLOGY 2022-04-21

Domestication of cranberry and blueberry began in the United States early 1800s 1900s, respectively, part owing to their flavors health-promoting benefits are now cultivated consumed worldwide. The industry continues face a wide variety production challenges (e.g. disease pressures) as well demand for higher-yielding cultivars with improved fruit quality characteristics. Unfortunately, molecular tools help guide breeding efforts these species have been relatively limited compared those other...

10.1101/2023.07.31.551392 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-08-02

Abstract Anthracnose fruit rot (AFR), caused by the fungal pathogen Colletotrichum fioriniae, is among most destructive and widespread disease of blueberry, impacting both yield overall quality. Blueberry cultivars have highly variable resistance against AFR. To date, this largely controlled applying various fungicides; thus, a more cost-effective environmentally conscious solution for AFR needed. Here we report three quantitative trait loci associated with in northern highbush blueberry...

10.1093/hr/uhad169 article EN cc-by Horticulture Research 2023-08-20

Societal impact statement Sour cherry ( Prunus cerasus L.) is an agriculturally valuable tree that produces fruits used in a range of culinary dishes, beverages, and other products. The progenitor species number origins sour remain unresolved. Here, we performed phylogenetic analyses plastid genomes nuclear genes from nine wild three historically important cultivars. Our identified fruticosa avium as the closest extant relatives tetraploid cherry. Furthermore, our revealed P. likely maternal...

10.1002/ppp3.10267 article EN cc-by Plants People Planet 2022-05-12

Abstract Premise The selection of Arabidopsis as a model organism played pivotal role in advancing genomic science. competing frameworks to select an agricultural‐ or ecological‐based species were rejected, favor building knowledge that would facilitate genome‐enabled research. Methods Here, we examine the ability models based on gene expression data predict tissue identity other flowering plants. Comparing different machine learning algorithms, trained and tested achieved near perfect...

10.1002/aps3.11621 article EN cc-by-nc Applications in Plant Sciences 2024-10-19

ABSTRACT The selection of Arabidopsis as a model organism played pivotal role in advancing genomic science, firmly establishing the cornerstone today ‘s plant molecular biology. Competing frameworks to select an agricultural- or ecological-based species, decentralize science and study multitude diverse were selected against favor building core knowledge species that would facilitate genome-enabled research could assumedly be transferred other plants. Here, we examine ability models based on...

10.1101/2023.08.20.554029 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2023-08-21

Francisella tularensis causes a disease called tularemia. Moreover, due to the highly infectious nature of F. tularensis, this organism can be used in bioterrorism. Therefore, combat threat, necessity for novel treatments is desired. replicates macrophages (phagocytic cells immune system derived from monocytes) during infection. We identified that Nevada Goldenrod extract (Salidago spectabilis) inhibited intracellular replication but did not alter bacterial growth culture, suggesting plant...

10.55632/pwvas.v89i1.208 article EN cc-by-nc Proceedings of the West Virginia Academy of Science 2017-04-04

MACKENZIE JACOBS, ELLIOT COLLINS, ROGER SEEBER, AND JOSEPH HORZEMPA, Department of Natural Sciences & Mathematics, West Liberty, WV 26074. Whitebark Pine Extract Augments Immune Responses that Diminish Bacterial InfectionFrancisella tularensis is a highly infectious bacterium causes tularemia. Currently, there are no legal treatments in the United States. Because nature F. tularensis, this organism can be used bioterrorism. Therefore, to counteract potential threat, development and...

10.55632/pwvas.v90i1.315 article EN cc-by-nc Proceedings of the West Virginia Academy of Science 2018-04-02

Francisella tularensis is a highly infectious bacterium that causes tularemia. Currently, there are no legal treatments in the United States. Because of nature F. tularensis, this organism can be used bioterrorism. Therefore, to counteract potential threat, development and discovery novel desired. During human infection, replicates phagocytic cells immune system such as monocytes macrophages. Through high throughput screen, we previously identified Whitebark Pine extract (Pinus albicaulis)...

10.55632/pwvas.v91i1.532 article EN cc-by-nc Proceedings of the West Virginia Academy of Science 2019-03-20

ABSTRACT Acylsugars are defensive, trichome-synthesized sugar esters produced in plants across the Solanaceae (nightshade) family. Although assembled from simple metabolites and synthesized by a relatively short core biosynthetic pathway, tremendous within- across-species acylsugar structural variation is documented To advance our understanding of diversity synthesis acylsugars within Nicotiana genus, trichome extracts were profiled genus coupled with transcriptomics-guided enzyme discovery...

10.1101/2022.02.25.482030 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-02-26
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