A5031889948- Retinal Diseases and Treatments
- Epilepsy research and treatment
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- EEG and Brain-Computer Interfaces
- Soft tissue tumors and treatment
- Retinal and Macular Surgery
- Retinal and Optic Conditions
- Statistical Methods in Clinical Trials
- Pharmacological Effects and Toxicity Studies
- Health Systems, Economic Evaluations, Quality of Life
- Machine Learning in Healthcare
- Dental Education, Practice, Research
- Vascular Malformations and Hemangiomas
- Vascular Malformations Diagnosis and Treatment
- Vitamin D Research Studies
- Health and Medical Education
- Functional Brain Connectivity Studies
- Allergic Rhinitis and Sensitization
- Pharmaceutical studies and practices
- Nuclear Structure and Function
- Innovations in Medical Education
- Historical Studies in Science
- Systemic Lupus Erythematosus Research
- Ophthalmology and Visual Impairment Studies
University of Pennsylvania
2014-2023
Beth Israel Deaconess Medical Center
2019-2021
Harvard University
2019-2020
Autonomous University of Aguascalientes
2013
Universidad de Antioquia
2006-2010
New York Eye and Ear Infirmary
2004-2009
New York Medical College
2009
Objective There are no validated methods for predicting the timing of seizures. Using machine learning, we sought to forecast 24‐hour risk self‐reported seizure from e‐diaries. Methods Data 5,419 patients on SeizureTracker.com (including count, type, and duration) were split into training (3,806 patients/1,665,215 patient‐days) testing (1,613 patients/549,588 sets with overlapping patients. An artificial intelligence (AI) program, consisting recurrent networks followed by a multilayer...
Purpose. To evaluate the effectiveness of lid hygiene and preservative-free artificial tears for treatment meibomian gland dysfunction (MGD) during a 6-week period. Methods. Suitable patients with MGD were educated about their disease instructed to begin regimen hygiene, which included application heated saline solution use nonpreserved tears. Baseline measurements obtained at time enrollment basic tear secretion test, breakup time, questionnaire grading symptoms (i.e., burning, irritation,...
Abstract Individual seizure rates are highly volatile, with large fluctuations from month‐to‐month. Nevertheless, changes in individual mean used to measure whether or not trial participants successfully respond treatment. This study aims quantify the challenges identifying treatment responders epilepsy. A power calculation was performed determine duration required detect a significant 50% decrease ( P < .05) for individuals. Seizure rate simulations were also number of people who would...
Abstract This study aimed to compare three commonly used analysis methods for clinical trials in epilepsy terms of statistical efficiency, nonefficacious exposure, and cost. A realistic seizure diary simulator was employed produce 102 000 trials, which were analyzed by the 50%‐responder rate method (RR50), median percentage change (MPC), time prerandomization (TTP). Half compared a placebo drug that 20% better, other half two placebos. The former calculate power; latter type 1 error rates....
Abstract Objective Previous research suggests that natural fluctuations in seizure rates within individuals have a quantifiable impact on therapeutic clinical trial outcomes. Methods A simulator estimated the statistical power of trials with typical design and without patients included who exhibited range means (1‐15 seizures/mo) standard deviations their baseline rates. Trial outcomes were evaluated using 50% responder rates, median percentage change, time to prerandomization. Results...
La enfermedad ósea sintomática es infrecuente en el hiperparatiroidismo primario (HPTP), y cuando se presenta puede transcurrir mucho tiempo antes del diagnóstico. Con objetivo de revisar actualizar conceptos acerca compromiso esquelético HPTP buscamos nuestros archivos casos pacientes quienes las manifestaciones iniciales o principales la hubieran sido alteraciones óseas. MATERIALES Y MÉTODOS: revisamos los Sección Ortopedia Departamento Patología Facultad Medicina, Universidad Antioquia...
De acuerdo con el Consejo Médico General del Reino Unido, pionero en la creación y actualización de programas estudios Medicina, plan las carreras Medicina debe tener como objetivo formar médicos que tengan principal preocupación cuidado los pacientes, aplicando sus conocimientos destrezas forma competente, ética utilizando habilidades para ser líderes analizar situaciones inciertas complejas (GMC, 2009). Para lograr lo anterior se proponen tres dominios globales competencias, a saber:...
El glomus es un tumor benigno de origen vascular más frecuentemente (75% los casos) localizado en la región subungueal dedos las manos. Se caracteriza por tríada dolor intenso e hipersensibilidad tanto al tacto como a temperatura. único tratamiento recomendado resección quirúrgica. Con base el archivo del Departamento Patología Facultad Medicina Universidad Antioquia, describimos caso una mujer 66 años con este tipo cuarto dedo mano izquierda; sus características clínicas, radiológicas...