- Molecular Sensors and Ion Detection
- Sulfur Compounds in Biology
- Luminescence and Fluorescent Materials
- Force Microscopy Techniques and Applications
- Polymer Surface Interaction Studies
- Bacterial biofilms and quorum sensing
- Advanced biosensing and bioanalysis techniques
- Nanofabrication and Lithography Techniques
- Nanoplatforms for cancer theranostics
- Covalent Organic Framework Applications
- Electrochemical sensors and biosensors
- 3D Printing in Biomedical Research
- Molecular Junctions and Nanostructures
- Metal-Organic Frameworks: Synthesis and Applications
- Neuroscience and Neural Engineering
- Cerebrospinal fluid and hydrocephalus
- RNA regulation and disease
- Monoclonal and Polyclonal Antibodies Research
- Bone Tissue Engineering Materials
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Peptidase Inhibition and Analysis
- Phase Equilibria and Thermodynamics
- Silk-based biomaterials and applications
- Nanocluster Synthesis and Applications
- Indoor Air Quality and Microbial Exposure
Shanxi Normal University
2022-2023
State Key Laboratory of Applied Organic Chemistry
2017-2021
Lanzhou City University
2018-2021
Lanzhou University
2017-2021
Sichuan Academy of Forestry
2020
Fuzhou University
2018
Northwest University
2015
Northwest University
2014
Ministry of Education of the People's Republic of China
2013-2014
Material (Belgium)
2014
Abstract Bacterial adhesion and colonization are complicated processes that depend on many factors, including surface chemistry, hydrophobicity, roughness. The contribution of each these factors has not been fully elucidated because most previous studies used different polymeric surfaces to achieve differences in properties. objective this study was modify hydrophobicity roughness one surface, eliminating the confounding chemistry. Mechanically assembled monolayer (MAM) preparation methods...
The mechanochromic luminescence phenomenon was first reported in the low-cost mechanochemical (MC) synthesis process of a covalent organic framework (COF-TpMA (MC)) prepared using triformylphloroglucinol (Tp) and melamine (MA) as precursors, which shows excellent performance hydroxyl radical (˙OH) detector living systems. This work not only new kind luminescent material but also exhibits close relationship between π-π stacking properties COF materials.
Two fluorescent, m-nitrophenol-substituted difluoroboron dipyrromethene dyes have been designed by nucleophilic substitution reaction of 3,5-dichloro-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY). Nonsymmetric and symmetric probes, that is. BODIPY 1 (with one nitrophenol group at the position 3) 2 two groups positions 3 5) were applied to ratiometric fluorescent glutathione detection. The detection is based on two-step aromatic probes in buffer solution containing CTAB. In first stage,...
A series of multifunctional ratiometric near-infrared fluorescent probes (CYOH-3, CYOH-4, CYOH-5, and CYOH-6) for esterase detection are designed by gradually changing the deflection plane twist in molecule. These composed different ring-structure trigger groups (from three-membered ring to six-membered ring) same luminescent group CYOH. show maximum absorption at ∼585 nm a fluorescence emission peak ∼655 ± 5 nm. In presence esterase, were hydrolyzed expose fluorophore CYOH (λabs = 690 nm,...
The escalating demand for long-context applications has intensified the necessity of extending LLM context windows. Despite recent fine-tuning approaches successfully expanding lengths, their high memory footprints, especially activations, present a critical practical limitation. Current parameter-efficient methods prioritize reducing parameter update overhead over addressing activation constraints. Similarly, existing sparsity mechanisms improve computational efficiency but overlook...
Abstract Bacterial adhesion on biomaterial surfaces is the initial step in establishing infections and leads to formation of biofilms. In this study, silicone was modified with different biopolymers silanes, including: heparin, hyaluronan, self‐assembled octadecyltrichlorosilane (OTS), fluoroalkylsilane (FAS). The aim provide a stable bacteria‐resistant surface by varying degree hydrophobicity structure. Escherichia coli (JM 109) investigated atomic force microscopy (AFM) scanning electron...
Diabetes is a metabolic disease caused by high blood sugar. Patients are often suffering from pressure and arteriosclerosis, which may even evolve into liver disease, kidney other diabetic complications. Dipeptide peptidase IV (DPP-IV) plays an important role in regulating sugar levels one of the targets for diagnosis treatment diabetes. Here, long-wavelength ratiometric fluorescent probe DCDHFNH2-dpp4 detecting DPP-IV was designed synthesized. used to detect healthy, tumor-bearing, mice,...
Covalent organic frameworks (COFs) have recently attracted much attention as potential photocatalysts for hydrogen production. The effective separation of photogenerated charges is a key objective to improve the photocatalytic activity COFs. Here, four COFs were synthesized through Schiff-base reaction investigate whether presence (simultaneous or not) triazine and ketone acceptors in improved electron-hole efficiency. Evidence indicated that charge was more efficient when simultaneously...
The immobilization of antibodies to sensor surfaces is critical in biochemical development. In this study, Poly(ethylene glycol) (PEG) and Jeffamine spacers were employed tether Escherichia coli K99 pilus antibody silicon wafer for the purpose improving orientation as well reducing steric hindrance. To illustrate effect spacer length, a variety linear polymers used covalently attach surfaces. Atomic Force Microscopy (AFM) X-ray photoelectron spectroscopy (XPS) characterize surface morphology...
Abstract Cerebrospinal fluid (CSF) shunts for the treatment of hydrocephalus are generally made silicone rubber. The growth bacterial colonies on surface leads to frequent CSF shunt complications. A systematic study effect modification Staphylococcus epidermidis adhesion and colonization was performed different incubation times by means colony counting scanning electron microscopy (SEM). Silicone modified with biopolymers silanes, including heparin, hyaluronan, octadecyltrichlorosilane...