A5001240167- Respiratory viral infections research
- Viral gastroenteritis research and epidemiology
- Pneumonia and Respiratory Infections
- Animal Virus Infections Studies
- Diabetes and associated disorders
- Cerebrospinal fluid and hydrocephalus
- Inflammatory Bowel Disease
- Pediatric Urology and Nephrology Studies
- Infectious Disease Case Reports and Treatments
- Viral Infections and Immunology Research
- Microscopic Colitis
- Neonatal Respiratory Health Research
- Adrenal Hormones and Disorders
- Pregnancy and Medication Impact
- Mitochondrial Function and Pathology
- Bacterial Infections and Vaccines
- Renal function and acid-base balance
- Wound Healing and Treatments
- Liver Disease Diagnosis and Treatment
- Streptococcal Infections and Treatments
- Radiation Therapy and Dosimetry
- Hepatitis B Virus Studies
- Diet and metabolism studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Diabetes Management and Research
Ben-Gurion University of the Negev
2019-2025
Soroka Medical Center
2019-2025
Schneider Children's Medical Center
2023-2024
Abstract Utilizing multiplex real time polymerase chain reaction (RT‐PCR) for rapid diagnosis of gastroenteritis, enables simultaneous detection multiple pathogens. A comparative analysis disease characteristics was conducted between cases with single and viruses. Rotavirus vaccine introduced in 2010, reaching a 70% coverage 2 years. All rectal swabs collected from diarrheic children (<5 years) December 2017 March 2022 were included. Detection the same viruses within months considered...
The Nancy Histological Index (NHI) was developed to assess histological disease activity in adult ulcerative colitis (UC) patients. However, data pediatrics is limited. Our aim determine whether the NHI correlates with different indices of pediatric UC We retrospectively reviewed rectal biopsies from 61 patients (median age 14.3 years), whom 34 (55.7%) were newly diagnosed. median Pediatric Ulcerative Colitis Activity (PUCAI) score among participants 30 (interquartile range 5-55). Most...
Our aims were to determine whether anion gap normalization time (AGNT) correlates with risk factors related the severity of diabetic ketoacidosis (DKA) in children, and characterize AGNT as a criterion for DKA resolution children admitted moderate or severe disease.A ten-year retrospective cohort study intensive care unit DKA. We used survival analysis approach changes serum glucose, bicarbonate, pH, following admission. Using multivariate analysis, we examined associations between patients'...
Abstract Aldosterone synthase deficiency (ASD) is a rare potentially life‐threatening genetic disorder that usually presents during infancy due to pathogenic variants in the CYP11B2 gene. Knowledge about Arab population scarce. Here, we present and analyze five Palestinian patients their different novel variants. Data on clinical presentation, electrolytes, plasma renin activity, steroid hormone levels of diagnosed with ASD were summarized. Sequencing gene exons was followed by evolutionary...
Streptococcus pneumoniae (Pnc) serotypes differ in invasive potential. We examined whether community-acquired alveolar pneumonia (CAAP) children carrying commonly recognized pneumococcal ([PnIST] 1, 5, 7F, 14, and 19A) differs from CAAP less (non-PnIST) or no Pnc (Pnc-neg).Children <5 years, visiting the only regional Pediatric Emergency Room, with radiologically proven were enrolled. Nasopharyngeal cultures processed for isolation serotyping. Clinical demographic characteristics recorded....
Abstract The Nancy Histological Index (NHI) is used to score histologic disease activity in patients with ulcerative colitis (UC). Our goal was assess the utility of NHI at diagnosis predicting clinical outcomes pediatric UC, comparison and endoscopic scores. We retrospectively reviewed data 106 children UC (59 [55.7%] females; median age 14.4 [11.2–15.9] years, Pediatric Ulcerative Colitis Activity [PUCAI] 35 [25–55]). During a follow‐up 116 (55–171) weeks, 33 (31.1%) required azathioprine...
Diabetic foot infections (DFIs) are associated with major morbidity, reduced quality of life and increased mortality. Osteomyelitis is a leading cause lower-extremity amputation in diabetic patients. We aimed to examine whether multifaceted strategy for treating hospitalized patients DFI effectively influenced microbiological culture results outcomes. A retrospective cohort-study 1100-bed, tertiary-care university hospital was conducted. Adult admitted the orthopedics department between 2015...
Telomeres are DNA sequences of tandem TTAGGG repeats that protect chromosome ends from degradation and instability. Constitutional loss-of-function telomerase mutations result in rapid telomere shortening, premature senescence cell death. Liver cirrhosis is rare has only been reported adults. We present five family members Bedouin-Muslim origin, all which carry the same mutation, yet demonstrate an extremely variable phenotypical presentation, including liver during early childhood.A...
Abstract Background Multiplex-PCR for the diagnosis of acute gastroenteritis (AGE) has allowed rapid detection multiple pathogens simultaneously but poses challenges in distinguishing between shedding and disease-causing pathogens. We aimed to evaluate epidemiology viral AGE compare clinical characteristics among 5 most common viruses. Methods SUMC is only hospital southern Israel serves a population ∼97,500 children &lt; years. Rotavirus vaccine was added national immunization program...