A5007690958- Multiple Sclerosis Research Studies
- Research in Social Sciences
- Education, Healthcare and Sociology Research
- Injury Epidemiology and Prevention
- Emergency and Acute Care Studies
- Trauma and Emergency Care Studies
- Social and Educational Sciences
- Musculoskeletal pain and rehabilitation
- Ergonomics and Musculoskeletal Disorders
- Muscle activation and electromyography studies
- Health disparities and outcomes
- Traffic and Road Safety
- Chronic Disease Management Strategies
- Occupational Health and Safety Research
- Systemic Sclerosis and Related Diseases
- School Health and Nursing Education
- Neonatal and fetal brain pathology
- Health, psychology, and well-being
- Family Support in Illness
- Motor Control and Adaptation
- Cerebral Palsy and Movement Disorders
- Tuberculosis Research and Epidemiology
- Childhood Cancer Survivors' Quality of Life
- Sleep and Work-Related Fatigue
- Rheumatoid Arthritis Research and Therapies
University of Southern Denmark
2013-2022
Danish National Institute of Public Health
2003-2020
University of Copenhagen
2004-2018
Rigshospitalet
2017-2018
Danish Multiple Sclerosis Center
2017
National Institute of Public Health
2007-2016
Austrian Road Safety Board
2010
National Institute of Occupational Health
1992-2001
Background: Obesity in late adolescence has been associated with an increased risk of multiple sclerosis (MS); however, it is not known if body size childhood MS risk. Methods: Using a prospective design we examined whether mass index (BMI) at ages 7–13 years was among 302,043 individuals the Copenhagen School Health Records Register (CSHRR). Linking CSHRR Danish registry yielded 774 cases (501 girls, 273 boys). We used Cox proportional hazards models to estimate hazard ratios (HRs) and 95%...
<h3>Objective</h3> To describe the pattern of development incidence multiple sclerosis (MS) over 60 years in Denmark with age-period-cohort analyses and seasonality birth. <h3>Methods</h3> Data on virtually all patients onset MS have since 1950 been prospectively recorded kept Danish Multiple Sclerosis Registry sources notification. Annualized rates per 100,000 were directly standardized to European Standard Population. <h3>Results</h3> We registered 19,536 cases clinical confirmed from...
Objectives This study explores the effects of mental and physical demands on muscular activity in use mouse keyboard computer work a time-pressed situation. Methods Twelve female subjects performed task with four combinations two forms input device (computer keyboard) levels demand (with without color word test). The time available for response was limited. Performance electromyography (EMG) were recorded forearm, shoulder, neck muscles. Results mean static 2-7% maximum EMG forearm extensor...
To investigate the effect of chronic comorbidity on time diagnosis multiple sclerosis (MS) and mortality in MS.We conducted a population-based, nationwide cohort study including all incident MS cases Denmark with first symptom between 1980 2005. diagnosis, we compared individuals without using multinomial logistic regression. mortality, used Cox regression time-dependent covariates, following participants from clinical onset until endpoint (death) or to end study, censuring at emigration.We...
<h3>Background</h3> Lifetime expectancy in multiple sclerosis (MS) is reduced. Few studies have had sufficient follow-up or number of patients to assess if survival has improved with time. However, a recent meta-analysis found no time-dependent change MS excess mortality across over decades. <h3>Objective</h3> To investigate whether short-term all-cause the total Danish population changed last six <h3>Patients and methods</h3> We included all recorded nationwide Registry definite probable...
Background: Studies of depression and anxiety in multiple sclerosis (MS) patients have reported higher rates MS than the general population. Objective: To estimate risk use tricyclic antidepressant selective serotonin reuptake inhibitors (SSRI) prescriptions, pre-diagnostic post-diagnostic period compared to background Methods: A cohort 5084 was included matched with a control population 24,771 persons linked nationwide registers. Logistic regression analyses were performed estimating odds...
Abstract Objectives The Danish Multiple Sclerosis Registry is the oldest operative and nationwide MS registry. We present with its history, data collection, scientific contribution, national international research collaboration. Materials Methods Detailed description of completeness, quality optimizing procedures, funding, legal, ethical protection issues are provided. Results total number registered cases clinical isolated syndrome multiple sclerosis since 1956 was by start May 2020 30,023...
Background: While social differences in childhood injuries are recognized, less is known about how and demographic relate to injury mechanism. The purpose of the study was reveal sociodemographic factors affect incidence unintentional home Danish children for specific mechanisms involved products. Methods: Information on 173 504 treated at emergency departments recorded period 1998–2003. information linked data including parents' education income family type, results were compared with those...
The authors studied injury mortality in Denmark among refugees and immigrants compared with that native Danes.
Background: Erythropoietin (EPO) is a part of an endogenous neuroprotective system in the brain and may address pathophysiological mechanisms progressive multiple sclerosis (MS). Objective: To evaluate treatment effect EPO on MS. Methods: This was single-center, randomized, double-blind, placebo-controlled phase 2 trial, which 52 patients with secondary or primary MS were allocated to recombinant (48,000 IU) placebo, administered intravenously 17 times during 24 weeks. Patients had Expanded...
A diagnosis of multiple sclerosis (MS) may impact the choice parenthood.To investigate number live births, abortions and ectopic pregnancies among persons with MS.From Danish Multiple Sclerosis Registry, we extracted data from all diagnosed MS 1960 to 1996 matched each person four reference persons. We used a negative binomial regression model for births Poisson pregnancies. The total fertility rate (TFR) during 1960-2016 annual in population were analysed.Persons had fewer children than...
Background It has been suggested that cognitive function in childhood is a modifiable risk factor for adult injury.This study examines the relationship between measured at age of 12 and 18 years fatal non-fatal injuries later life. MethodsA total 11 532 males born Copenhagen, Denmark 1953 were followed from 1978 until 2001 with outcomes (death hospital admission unintentional injury) obtained national registers.At years, 7987 these cohort members had completed questionnaire, which included...