Vertebral fractures could lead to reduced physical, social and mental functioning, loss of personal independence. Therefore, during the treatment osteoporosis, it has become necessary examine changes in everyday well-being health related quality life (HRQOL). To that effect, this study aims translate, culturally adapt, validate Serbian version Quality Life Questionnaire European Foundation for Osteoporosis (QUALEFFO-41) patients with vertebral fractures. Nine female osteoporosis participated...

Abstract Objective: Cross-cultural validation of the Serbian version Modified Falls Efficacy Scale (MFES). Methods: This cross-sectional study involved 257 women aged 65 years and above who were referred for dual-energy x-ray absorptiometry examination at Railway Healthcare Institute in Belgrade, Serbia, between January April 2016. Data collection comprised a sociodemographic questionnaire Geriatric Depression Scale-Short Form (GDS-SF) questionnaire, data related to fractures, level physical...

The aim of the authors this study was to develop a short version Osteoporosis Knowledge Assessment Tool be used for target population young adult Serbian females as an easily implemented add-on questionnaire. 20-item translated and culturally adapted using Principles Good Practice Translation Cultural Adaptation Process Patient-Reported Outcomes Measures. validation conducted on sample 250 female students studying at Faculty Pharmacy University Belgrade, during two-month period...

Klippel-Feil syndrome is defined as congenital fusion of two or more cervical vertebrae. In this article, we report a 55-year-old male patient with one-year history neck pain, headaches, and one episode syncope after severe trauma. X-rays magnetic resonance imaging spine revealed fused vertebral bodies C2-C5. The major anomalies associated (small stature, thoracic kyphoscoliosis, lumbar scoliosis, restricted opening mouth, bilateral sensorineural hearing loss) well multiple minor (mild face...

In the recent years, iodine was associated to development of apoptosis in thyroid diseases. The aim present study is determine expression pro-apoptotic and anti-apoptotic proteins, Bax Bcl-2, a Wistar rat experimental model thyroiditis induced by administration different doses potassium iodide. Immunohistochemical staining done with chromogen diaminobenzidine on avidin-biotin peroxidase using Animal Research Kit (ARK), stained antibodies Bcl-2 proteins. intensity distribution positive were...

Background: Many treatments have been tried in therapy systemic sclerosis (SSc) patients but use of hyperbaric oxygen (HBOT) is very limited. Objectives: To assess the effects HBOT to quality life and state microcirculation SSc patients. Methods: 18 female aged 29-68 years (mean 57 years) with limited digital or leg ulcers were included this work. The protocol comprised 20 sessions 5 day/weekly, 60 min, 100% at 2.2 ATA. treated evaluated baseline after sessions. Evaluation consisted physical...

Abstract Statins might cause and/or aggravate the immune-mediated myositis in patients on long-term, stable treatment. We provide a case of polymyositis with an immunological background and gastrointestinal urinary manifestations patient atorvastatin treatment for past six years. The diagnose was established based clinical symptoms signs, electromyography laboratory test results (elevated aspartate aminotransferase 279 U/L, reference range 0–40 U/L; alanine 198 0–33 lactate dehydrogenase...

This study aims to assess the possible relationship between 99mTc-pertechnetate hand perfusion scintigraphy (HPS) and nailfold capillaroscopy (NC) in systemic sclerosis (SSc) patients.The group consisted of 25 SSc patients (6 males; 19 females; mean age 54.2±9.7 years; range, 32 67 years), 18 female with primary Raynaud's phenomenon (PRP) (mean 47.1±9.5 34 65 years) 10 healthy individuals (3 males, 7 52.7±12.6 37 73 years). NC HPS were performed all examinees. The capillaroscopic findings...

<h3>Objective</h3> To investigate the timing of transition through different patterns nailfold microvascular damage in systemic sclerosis (SSc) patients and to determine significance this transition. <h3>Methods</h3> In period January 2012 December 2017, 400 SSc were followed up by videocapillaroscopy (NVC) same operator (SPD) every 6 months. Demographic, clinical laboratory data recorded. The capillaroscopic findings classsified as normal, nonspecific or scleroderma pattern ("early",...

<h3>Objectives</h3> To analyze the effects of cyclophosphamide (CYC) pulse therapy on parameters lung function in patients (pts) with systemic sclerosis (SSc). <h3>Methods</h3> Thirty pts SSc (25 women and 5 men, aged 30-70 years, mean disease duration &lt;2 years) were included this study. The main reason for beginning CYC was decrease forced vital capacity (FVC) under 80% or single-breath diffusing carbon monoxide (DLco) 70% predictive value. Based relationships FVC%/DLco% divided into two...

<h3>Objectives</h3> The aim of this study was to assess sensitivity and specificity ^99mTc-pertechnetate hand perfusion scintigraphy in patients with Raynaud9s phenomenon (RP). <h3>Methods</h3> population consisted 10 healthy individuals (mean age 57 years), 18 primary RP 48 years) 25 secondary within systemic sclerosis (SSc) 54 years). Gamma-camera dynamic first-pass during the first 60 sec a static after 5 min were recorded following bolus injection via cubital vein. Regions...

<h3>Background</h3> Systemic lupus erythematosus (SLE) is a multiorgan disease with protean manifestations and its diagnosis can pose considerable challenge. <h3>Objectives</h3> The aim of the study was to analyze clinical laboratory at onset SLE compare ACR SLICC criteria for classification SLE. <h3>Methods</h3> A retrospective well characterized cohort 100 patients undertaken. All met four or more updated (range 4–8). following data were collected: age, gender, initial manifestations, time...

<h3>Background</h3> Provisional major criteria for the diagnosis of very early systemic sclerosis (VESSc) proposed EULAR Scleroderma Trial and Research Group (EUSTAR) are Raynaud's phenomenon (RP), positive autoantibodies (antinuclear, anticentromere-ACA, antitopoisomerase I- ATA) scleroderma pattern nailfold capillary changes (SPNCC)1. However, reports about prognostic value this antibodies in VESSc inconclusive. <h3>Objectives</h3> To assess SPNCC, ACA ATA development patients (pts) with...

<h3>Background</h3> The aim of this study was to assess possible relationship between the altered blood perfusion at hands analysed by ^99mTc-pertechnetate hand scintigraphy (^99mTcPHPS) and, morphological microvascular abnormalities detected nailfold capillaroscopy (NC) in SSc patients. <h3>Methods</h3> group consisted 25 patients with (14 diffuse SSc, and 11 limited SSc) 28 control subjects (18 primary RP, and10 healthy individuals). NC ^99mTcPHPS performed...