- Electroconvulsive Therapy Studies
- Treatment of Major Depression
- Functional Brain Connectivity Studies
- Schizophrenia research and treatment
- Maternal Mental Health During Pregnancy and Postpartum
- Advanced Neuroimaging Techniques and Applications
- Education, Healthcare and Sociology Research
- Transcranial Magnetic Stimulation Studies
- Cardiac Health and Mental Health
- Mental Health and Psychiatry
- Psychiatric care and mental health services
- Advanced MRI Techniques and Applications
- Bipolar Disorder and Treatment
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Diet and metabolism studies
- Takotsubo Cardiomyopathy and Associated Phenomena
- Child and Adolescent Psychosocial and Emotional Development
- Child and Adolescent Health
- Intensive Care Unit Cognitive Disorders
- Stress Responses and Cortisol
- Sleep and related disorders
- Psychosomatic Disorders and Their Treatments
- Attention Deficit Hyperactivity Disorder
- Human-Animal Interaction Studies
- Health, psychology, and well-being
Glostrup Hospital
2016-2025
University of Copenhagen
2015-2025
Copenhagen University Hospital
2016-2024
Sygehus Sønderjylland
2024
Statens Serum Institut
2024
University of Southern Denmark
2024
Mental Health Services
2015-2024
Capital Region of Denmark
2015-2024
The Capital Region Pharmacy
2024
Center for Clinical Research and Prevention
2022-2023
To identify and test the predictive power of demographic, obstetric, psychosocial risk factors postpartum depression.Community-based, prospective follow up study based on questionnaires past history psychiatric disease, psychological distress social support during pregnancy depression at four months after delivery. Obstetric files were collected time birth.Antenatal care clinic delivery ward, Aarhus University Hospital, Denmark.6,790 women giving birth between 1 January 1994 31 December...
Major depression is a mood disorder that often accompanied by the impairment of cognitive functions. Although suggestive, large range existing neuropsychological, neuropsychiatric, and, lately, neuroimaging investigations have not yet given consistent picture psychological and biological disturbances involved in this psychiatric disorder. The present study functions was part an extensive investigation, including neuropsychological testing, examination, neuroimaging. A representative sample...
The effect of referring patients from a clinical setting to pragmatic exercise intervention for depressive symptoms, cognitive function, and metabolic variables has yet be determined.Outpatients with major depression (DSM-IV) were allocated supervised aerobic or stretching groups during three months period. primary outcome was the Hamilton score (HAM-D(17)). Secondary outcomes cardiovascular risk markers, employment related outcomes.56 participants versus 59 group. Post mean difference...
Objective: We wanted to explore associations between clinical symptoms of depression and the blood flow specific regions brain. Furthermore, we compare regions‐of‐interest (ROI) method with functions‐of‐interest (FOI) approach. Method: The resting 42 ROI in brain was obtained positron emission tomography (PET) imaging representative in‐patients major 47 matched healthy controls. Results: patients had increased hippocampus, cerebellum, anterior cingulate gyrus, basal ganglia. A strong...
Stroop's test and the Verbal Fluency are commonly argued to be measures of integrity prefrontal cortex. This assumption has only some degree been confirmed by lesion studies. In present study, Positron Emission Tomography (PET) with H(2)(15)O was used further validate as frontal lobe function; both tests were implemented activation paradigms during scanning normal middleaged individuals. Stroop interference found activate left anterior cingulate cortex, supplementary motor thalamus,...
Some 5%-15% of all women experience postpartum depression (PPD), which for many is their first psychiatric disorder. The purpose this study was to estimate the incidence affective disorder (AD), duration treatment, and rate subsequent AD other episodes in a nationwide cohort with no prior history.Linking information from several Danish national registers, we constructed 457,317 primiparous mothers birth (and births) 1 January 1996 31 December 2013 (a total 789,068 hospital contacts and/or...
Abstract Background Previous studies have suggested that visiting dogs can positive effects on elderly people in nursing homes. We wanted to study the of biweekly dog visits sleep patterns and psychiatric well‐being people. Methods A total 100 residents (median age: 85.5 years; [79; 90]) from four homes were randomly assigned receive for 6 weeks a person accompanied by either dog, robot seal ( PARO ), or soft toy cat. Sleep measured using actigraphy technology before, during (the third sixth...
Previous studies suggest that contact with dogs can positively affect the wellbeing of elderly people in nursing homes, but there is a lack research investigating causal pathways these effects. One such path- way may relate to behavioral responses when interacting dog. The present study compared immediate home residents bi-weekly visits from person accompanied by either dog, robot seal (PARO®), or soft toy cat, using randomized controlled design. A total 100 com- pleted study. Each...
The aim of this study was to investigate women who had first‐episode psychosis within 1 year after parturition. Danish Psychiatric Central Register and the Medical Birth were linked identify all admitted for first time a psychiatric department in Århus County with psychotic episode. Fifty cases found, giving frequency delivery per 1000. First‐episode disease month postpartum occurred case 2000 deliveries. age distribution corresponded that background population, but primiparous more often...
Background Several studies suggest that patients with late-onset major depression (MD) have an increased load of cerebral white-matter lesions (WMLs) compared age-matched controls. Vascular risk factors such as hypertension and smoking may confound findings. Our aim was to investigate the association between localization WMLs in MD respect vascular factors. Method We examined 22 consecutive first-episode age- gender-matched controls using whole-brain magnetic resonance imaging (MRI). The...
Studies investigating mortality secondary to electroconvulsive therapy (ECT) are few.To assess the risk of from natural and unnatural causes among ECT recipients compared with other psychiatric in-patients over a 25-year period.Register-based cohort study all admitted hospital 1976 2000. Cause-specific was analysed using log-linear Poisson regression.There were 783 deceased who had received 5781 not. Patients lower overall rate (RR=0.82, 95% CI 0.74-0.90) but slightly higher suicide...
To determine whether long-term course of treated major depression has an effect on the structure brain and hippocampal volume.An 11-year follow-up procedure was used with data collection at baseline again follow-up. Tensor-based morphometry (TBM) automatic volume measure performed different datasets. The dataset consisted T1-weighted magnetic resonance images (MRIs) 24 in-patients suffering from 33 healthy controls. second MRIs 31 remitted depressive patients 36 longitudinal 19 matched...
Background Delirium in patients admitted to the intensive care unit ( ICU ) is a serious complication potentially increasing morbidity and mortality. The aim of this study was investigate impact fluctuating sedation levels on incidence delirium . Methods A prospective cohort adult at three multidisciplinary ICUs Richmond Agitation Sedation Scale RASS Confusion Assessment Method for were used least twice day. Results detected once 65% n = 640). Delirious significantly older, more critically...