A5062350824- COVID-19 Impact on Reproduction
- Maternal and Perinatal Health Interventions
- Neonatal Respiratory Health Research
- Maternal and fetal healthcare
- Pregnancy and preeclampsia studies
- Global Maternal and Child Health
- Maternal Mental Health During Pregnancy and Postpartum
- COVID-19 and healthcare impacts
- Neonatal and fetal brain pathology
- Diversity and Career in Medicine
- Neuroscience of respiration and sleep
- Global Health and Surgery
- Cardiac, Anesthesia and Surgical Outcomes
- Reproductive System and Pregnancy
- Infant Development and Preterm Care
- Global Health Care Issues
- Pregnancy and Medication Impact
- Parvovirus B19 Infection Studies
- Hip and Femur Fractures
- Climate Change and Health Impacts
- Gestational Diabetes Research and Management
- Reproductive Health and Contraception
- Congenital Diaphragmatic Hernia Studies
- Trauma and Emergency Care Studies
- Blood donation and transfusion practices
Lund University
2017-2025
Skåne University Hospital
2017-2025
Social Change and Development
2021-2024
Harvard University
2022-2024
Harvard Global Health Institute
2024
National Institute for Health Research
2024
University of Birmingham
2024
St George's, University of London
2024
University of the Witwatersrand
2024
Massachusetts General Hospital
2023
Perinatal death is an increasingly important problem as the coronavirus disease 2019 (COVID-19) pandemic continues, but mechanism of has been unclear.To evaluate role placenta in causing stillbirth and neonatal following maternal infection with COVID-19 confirmed placental positivity for severe acute respiratory syndrome 2 (SARS-CoV-2).Case-based retrospective clinicopathologic analysis by a multinational group 44 perinatal specialists from 12 countries autopsy pathology findings 64...
Multi-country studies assessing the quality of maternal and newborn care (QMNC) during COVID-19 pandemic, as defined by WHO Standards, are lacking.Women who gave birth in 12 countries European Region from March 1, 2020 - 15, 2021 answered an online questionnaire, including 40 Standard-based Quality Measures.21,027 mothers were included analysis. Among those experienced labour (N=18,063), 41·8% (26·1%- 63·5%) difficulties accessing antenatal care, 62% (12·6%-99·0%) not allowed a companion...
To correlate clinical outcomes to pathology in SARS-CoV-2 infected placentas stillborn and live-born infants presenting with fetal distress.
Context.— SARS-CoV-2 can undergo maternal–fetal transmission, heightening interest in the placental pathology findings from this infection. Transplacental transmission is typically accompanied by chronic histiocytic intervillositis together with necrosis and positivity of syncytiotrophoblast for SARS-CoV-2. Hofbauer cells are macrophages that have been involved viral diseases, including HIV Zika virus, but their involvement unknown. Objective.— To determine whether extend beyond to enter...
Abstract Background Exclusive breastfeeding is the optimal infant nutrition, providing infants immunoprotection against many diseases including SARS-CoV-2 infection. Restrictions during COVID-19 pandemic may have negatively affected practices in maternity care facilities. The aims of study were to examine exclusive rates at discharge over time and identify factors associated with pandemic. Methods A cross-sectional survey was conducted among mothers who gave birth a facility World Health...
This article includes Author Insights, a video abstract available at https://vimeo.com/bjog/authorinsights16682
Existing healthcare systems have been put under immense pressure during the COVID-19 pandemic. Disruptions in essential maternal and newborn services come from even high-income countries within World Health Organization (WHO) European Region.To describe quality of care pregnancy childbirth, as reported by women themselves, pandemic Sweden, using WHO 'Standards for improving health facilities'.Using an anonymous, online questionnaire, ≥18 years were invited to participate if they had given...
Neonatal hypoxic ischemic encephalopathy (HIE) is a devastating condition resulting from sustained lack of oxygen during birth. The interest in identifying relevant biomarker HIE has thrown into limelight the role protein S100B as clinical diagnostic marker brain damage neonates.To evaluate value S100B, measured umbilical cord blood immediately after birth, useful diagnosis Sarnat stages II-III well for long-term mortality and morbidity.Protein was analyzed sampled at birth 13 newborns later...
It has been proposed that pregnant women and their fetuses may be particularly at risk for poor outcomes due to the coronavirus (COVID-19) pandemic. From few case series are available in literature, with high pregnancies have associated higher morbidity. suggested pregnancy induced immune responses cardio-vascular changes can exaggerate course of COVID-19 infection.A 26-year old Somalian woman (G2P1) presented a nine-day history shortness breath, dry cough, myalgia, nausea, abdominal pain...
The COVID-19 pandemic has had a profound effect on the emotional well-being of expecting mothers. Sweden's unique strategy for managing involved no national lockdown. Emphasis was instead placed limiting crowding and asking citizens to practice social distancing measures.To gain deeper understanding how women not infected by SARS-CoV-2 experienced pregnancy during in Sweden.This qualitative study with reflective lifeworld approach. Fourteen that contracted who were pregnant first second wave...
Mitigation measures implemented in response to the COVID-19 pandemic led significant changes maternity care across Europe, including restrictions on companions during labor and birth. This cross-sectional study explores association between presence of a companion choice positive perception birth experience. Additionally, it health professionals' attention, assistance, availability We utilized structured, validated online questionnaire, available 25 languages, assess quality maternal from...
With the disease burden increasing daily, there is a lack of evidence regarding impact COVID-19 in pregnancy. Healthy pregnant women are still not regarded as susceptible group despite physiological changes that make more vulnerable to severe infection. However, high-risk pregnancies may be associated with respiratory failure, outlined this report. We discuss importance timely delivery and antenatal steroid administration critically ill patient. A 27-year-old woman (gravida 2, para 1) type I...
As the COVID-19 pandemic intensified global health crisis, containment of SARS-CoV-2 infection in pregnancies, and inherent risk vertical transmission virus from mother-to-fetus (or neonate) poses a major concern. Most COVID-19-Pregnancy patients showed mild to moderate pneumonia with no pregnancy loss congenital virus; however, an increase hypoxia-induced preterm deliveries was apparent. Also, breastmilk several mothers tested negative for virus. Taken together, natural barrier function...
To compare ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) and glial fibrillary acidic protein (GFAP) concentrations in umbilical cord blood of neonates who develop Sarnat stage II-III hypoxic-ischemic encephalopathy (HIE) to healthy controls, relate the severity neurology long-time outcomes.Cord sera 15 with HIE 31 matched controls were analyzed for UCH-L1 GFAP. Comparisons performed artery pH, amplitude-integrated electroencephalography (aEEG), HIE, death or sequelae up an age 6 years....
Abstract Introduction Maternal‐neonatal healthcare services were severely disrupted during the COVID‐19 pandemic in even high‐income countries within World Health Organization (WHO) European Region. The objective of this study was to compare trends quality maternal and neonatal care (QMNC) Sweden Norway 12 other from WHO Region pandemic, identify domains for improvement. Material Methods This cross‐sectional included women giving birth Europe March 1, 2020 December 31, 2022. Women answered...
Abstract Introduction Despite much literature on reference values of acid‐base status in umbilical cord blood at birth, there are as yet no studies performed to determine gestational age‐dependent references venous and preterm standards. Similarly, the normal range Apgar scores for term infants has not been determined. Material methods Data were obtained from maternity units Skåne University Hospital, Malmö Lund, Sweden, 2001 2010. Validated paired arterial pH 27 175 newborns, whom 18 584...
Objectives Develop and validate a WHO Standards-based online questionnaire to measure the quality of maternal newborn care (QMNC) around time childbirth from health workers’ perspective. Design Mixed-methods study. Setting Six countries European Region. Participants methods The is based on lessons learnt in previous studies, was developed three sequential phases: (1) Quality Measures were prioritised content, construct face validity assessed through Delphi involving multidisciplinary board...