- Blood properties and coagulation
- Erythrocyte Function and Pathophysiology
- Rheology and Fluid Dynamics Studies
- Hemoglobinopathies and Related Disorders
- Fluid Dynamics and Turbulent Flows
- Micro and Nano Robotics
- Platelet Disorders and Treatments
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Venous Thromboembolism Diagnosis and Management
- Thermal Expansion and Ionic Conductivity
- Microfluidic and Bio-sensing Technologies
- Adhesion, Friction, and Surface Interactions
- Rare-earth and actinide compounds
- Polymer Surface Interaction Studies
- Magnetic and transport properties of perovskites and related materials
- Healthcare cost, quality, practices
- Characterization and Applications of Magnetic Nanoparticles
- Stochastic processes and statistical mechanics
- Cardiac, Anesthesia and Surgical Outcomes
- Force Microscopy Techniques and Applications
- Neonatal Health and Biochemistry
- Lattice Boltzmann Simulation Studies
- Advanced Thermodynamics and Statistical Mechanics
Université Grenoble Alpes
2021-2024
Laboratoire Interdisciplinaire de Physique
2021-2024
Centre National de la Recherche Scientifique
2021-2024
Centre Interdisciplinaire de Nanoscience de Marseille
2024
Aix-Marseille Université
2024
Mohammed V University
2022
Transport of deformable particles in a honeycomb network is studied numerically. It shown that the particle deformability has strong impact on their distribution network. For sufficiently soft particles, we observe short memory behavior from one bifurcation to next, and overall consists random partition exhibiting diffusionlike transport. On contrary, stiff enough undergo biased whereby they follow deterministic at bifurcations, due long memory. This leads lateral ballistic drift small...
Red blood cells (RBCs) are responsible for transporting oxygen and various metabolites to tissues organs, as well removing waste. Several cardiovascular diseases can impair these functions. For instance, in diabetes, increased RBC aggregation lead occlusion, thereby depriving of efficient delivery. Interestingly, adhesion occurs not only disease states but also under physiological conditions, with the key difference being that is reversible healthy situations. This paper focuses on numerical...
Aggregates of red blood cells (RBCs) are normally dissociated reversibly by moderate flow stresses. Numerical simulations show that the RBCs doublet may be robust even for very high shear stress compromising oxygen delivery to organs and tissues. A link with pathological conditions (several common diseases) is demonstrated.
This simulation study shows that the occurrence of multilobe shapes for red blood cells is robust and does not require cytoskeleton elasticity in model, a marked contrast with previous claims. Multilobes are caused by membrane tension due to hydrodynamic stress. result advances considerably our understanding shape revelation under flow.
The rheological behavior and dynamics of a vesicle suspension, serving as simplified model for red blood cells, are explored within Poiseuille flow under the Stokes limit. Investigating response has led to identification novel solutions that complement previously documented forms like parachute slipper shapes. This study brought light existence alternative configurations, including fully off-centered form multilobe structure. unveils presence two distinct branches associated with shape. One...
Exploring how the shape of red blood cells influences their flow properties, this study uses numerical simulations to analyze changes from healthy bi-concave forms abnormal spherical shapes associated with disorders like spherocytosis. The research reveals complex, non-monotonic relationships between cell and rate across varying channel widths, its impact on perfusion.
The glycocalyx is a complex layer of carbohydrate and protein molecules that surrounds the cell membrane many types mammalian cells. It serves several important functions, including adhesion communication, maintain shape stability, especially in case erythrocytes. Alteration composition represents cardiovascular health threatening. For example, diabetes mellitus erythrocytes endothelial cells known to be impaired, potential source blood occlusion microcirculation, which may lead blindness,...
The presence of platelets near vessel walls is crucial for clot formation to stop bleeding. We examine platelet margination influenced by red blood cell (RBC) aggregation through numerical simulation. Our findings indicate that moderate strong RBC enhances in microcirculation, thereby improving the capacity This mechanism offers a natural counteraction against major bleeding conditions such as diabetes, where commonly observed.
Despite decades of research on blood flow, an analogue Navier-Stokes equations that accurately describe flow properties has not been established yet. The reason behind this is the seem \`a priori non universal as they depend various factors such global concentration red cells (RBCs) and channel width. Here, we have discovered a law when stress strain rate are measured at given local RBCs concentration. However, must be determined in order to close problem. We propose non-local diffusion...
The glycocalyx is a complex layer of carbohydrate and protein molecules that surrounds the cell membrane many types mammalian cells. It serves several important functions, including adhesion communication, maintain shape stability, especially in case erythrocytes. Alteration composition represents cardiovascular health threatening. For example, diabetes mellitus erythrocytes endothelial cells known to be impaired, potential source blood occlusion microcirculation, which may lead blindness,...
A polymer brush is a passive medium. At equilibrium the knowledge of its chemical composition and thickness enough for full system characterization. However, when exposed to fluid flow it reveals much more intriguing nature, in which filamentous protrusions way they interact among themselves with surrounding are outmost importance. Here we investigate such rich behavior via numerical simulations. We focus on hydrodynamic response at low Reynolds numbers, observing significant reduction...